Search Count: 8
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Complex Of Novel Maytansinoid M24 Bound To T2R-Ttl (Two Tubulin Alpha/Beta Heterodimers, Rb3 Stathmin-Like Domain, And Tubulin Tyrosine Ligase)
Organism: Rattus norvegicus, Gallus gallus, Sus scrofa
Method: X-RAY DIFFRACTION Resolution:2.21 Å Release Date: 2021-12-22 Classification: STRUCTURAL PROTEIN Ligands: GTP, MG, CA, CL, EDO, GDP, MES, XQ4, ACP |
Organism: Rattus norvegicus, Gallus gallus, Sus scrofa
Method: X-RAY DIFFRACTION
Release Date: 2021-12-22
Ligands: GTP, MG, CA, CL, EDO, GDP, MES, XQ4, ACP
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Discovery Of A Stable Macrocyclic O-Aminobenzamide Hsp90 Inhibitor Capable Of Significantly Decreasing Tumor Volume In A Mouse Xenograft Model.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.57 Å Release Date: 2011-07-13 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 06T |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-07-13
Ligands: 06T
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Macrocyclic Lactams As Potent Hsp90 Inhibitors With Excellent Tumor Exposure And Extended Biomarker Activity.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.58 Å Release Date: 2011-05-11 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 06H |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-05-11
Ligands: 06H
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Design And Sar Of Macrocyclic Hsp90 Inhibitors With Increased Metabolic Stability And Potent Cell-Proliferation Activity
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.57 Å Release Date: 2011-04-06 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 05S, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-04-06
Ligands: 05S, DMS
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Pdk-1 In Complex With The Inhibitor Compound-8I
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2010-02-16 Classification: TRANSFERASE Ligands: 8I1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-02-16
Ligands: 8I1
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Pdk1 In Complex With Compound 8H
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2010-02-09 Classification: TRANSFERASE Ligands: 8H1, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-02-09
Ligands: 8H1, SO4
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Structure Of Hcv Ns5B Bound To An Anthranilic Acid Inhibitor
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2007-10-02 Classification: TRANSFERASE Ligands: 452 |
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION
Release Date: 2007-10-02
Ligands: 452
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Structure Of Hcv Ns5B Bound To An Anthranilic Acid Inhibitor
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2007-10-02 Classification: TRANSFERASE Ligands: 617 |
Organism: Hepatitis c virus subtype 1b
Method: X-RAY DIFFRACTION
Release Date: 2007-10-02
Ligands: 617