Search Count: 48
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Cryo-Em Structure Of Lrp2 At Ph 7.5
Organism: Mus musculus
Method: ELECTRON MICROSCOPY Release Date: 2023-02-08 Classification: MEMBRANE PROTEIN Ligands: NGA, NAG, CA |
Organism: Mus musculus
Method: ELECTRON MICROSCOPY
Release Date: 2023-02-08
Ligands: NGA, NAG, CA
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Cryo-Em Structure Of Lrp2 At Ph 5.2
Organism: Mus musculus
Method: ELECTRON MICROSCOPY Release Date: 2023-02-08 Classification: MEMBRANE PROTEIN Ligands: NAG, NGA, CA |
Organism: Mus musculus
Method: ELECTRON MICROSCOPY
Release Date: 2023-02-08
Ligands: NAG, NGA, CA
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Crystal Structure Of An Asymmetric Dimer Of Fgf Receptor 3 Kinases Trapped In A-Loop Tyrosine Transphosphorylation Reaction
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2020-01-22 Classification: TRANSFERASE Ligands: ACP, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-22
Ligands: ACP, SO4
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Crystal Structure Of Fgf Receptor 2 Tyrosine Kinase Domain Harboring The D650V Activating Mutation
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.86 Å Release Date: 2017-02-22 Classification: TRANSFERASE Ligands: SO4, ANP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: SO4, ANP
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Crystal Structure Of The Tyrosine Kinase Domain Of Fgf Receptor 2 Harboring A E565A/D650V Double Gain-Of-Function Mutation
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2017-02-22 Classification: TRANSFERASE Ligands: SO4, ACP, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: SO4, ACP, MG
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Crystal Structure Of The Tyrosine Kinase Domain Of Fgf Receptor 2 Harboring A N549H/E565A Double Gain-Of-Function Mutation
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.91 Å Release Date: 2017-02-22 Classification: TRANSFERASE Ligands: SO4, ACP, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: SO4, ACP, MG
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Crystal Structure Of The Tyrosine Kinase Domain Of Fgf Receptor 2 Harboring An E565A/K659M Double Gain-Of-Function Mutation
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2017-02-22 Classification: TRANSFERASE Ligands: FLC, SO4, ACP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: FLC, SO4, ACP
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Crystal Structure Of The Activated Fgf Receptor 2 (Fgfr2) Kinase Domain In Complex With The Csh2 Domain Of Phospholipase C Gamma (Plcgamma)
Organism: Homo sapiens, Rattus norvegicus
Method: X-RAY DIFFRACTION Resolution:2.61 Å Release Date: 2016-02-03 Classification: Transferase/Hydrolase Ligands: ACP, MG |
Organism: Homo sapiens, Rattus norvegicus
Method: X-RAY DIFFRACTION
Release Date: 2016-02-03
Ligands: ACP, MG
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Discovery Of Novel Oxazepine And Diazepine Carboxamides As Two New Classes Of Heat Shock Protein 90 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2015-03-04 Classification: Chaperone/chaperone Inhibitor Ligands: 40W |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-03-04
Ligands: 40W
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Discovery Of Novel Oxazepine And Diazepine Carboxamides As Two New Classes Of Heat Shock Protein 90 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2015-03-04 Classification: Chaperone/chaperone Inhibitor Ligands: 40Y, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-03-04
Ligands: 40Y, GOL
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Discovery Of Novel Oxazepine And Diazepine Carboxamides As Two New Classes Of Heat Shock Protein 90 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2015-03-04 Classification: Chaperone/chaperone Inhibitor Ligands: 40X, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-03-04
Ligands: 40X, GOL
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Discovery Of Novel Oxazepine And Diazepine Carboxamides As Two New Classes Of Heat Shock Protein 90 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.86 Å Release Date: 2015-03-04 Classification: Chaperone/chaperone Inhibitor Ligands: 40Z, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-03-04
Ligands: 40Z, GOL
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Identification Of Novel Hsp90/Isoform Selective Inhibitors Using Structure-Based Drug Design. Demonstration Of Potential Utility In Treating Cns Disorders Such As Huntington'S Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.82 Å Release Date: 2014-12-24 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 2Q8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-24
Ligands: 2Q8
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Crystal Structure Of Fgf Receptor (Fgfr) 4 Kinase Harboring The V550L Gate-Keeper Mutation In Complex With Fiin-2, An Irreversible Tyrosine Kinase Inhibitor Capable Of Overcoming Fgfr Kinase Gate-Keeper Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2014-10-29 Classification: Transferase/transferase inhibitor Ligands: 37O |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-10-29
Ligands: 37O
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Crystal Structure Of Fgf Receptor (Fgfr) 4 Kinase Domain Harboring The V550L Gate-Keeper Mutation
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.68 Å Release Date: 2014-10-29 Classification: TRANSFERASE Ligands: SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-10-29
Ligands: SO4
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Crystal Structure Of Fgf Receptor (Fgfr) 4 Tyrosine Kinase Domain
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2014-10-29 Classification: TRANSFERASE Ligands: SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-10-29
Ligands: SO4
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Crystal Structure Of The Tyrosine Kinase Domain Of Fgf Receptor 4 In Complex With Ponatinib
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2014-10-29 Classification: Transferase/transferase inhibitor Ligands: SO4, 0LI |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-10-29
Ligands: SO4, 0LI
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Identification Of Novel Hsp90/Isoform Selective Inhibitors Using Structure-Based Drug Design. Demonstration Of Potential Utility In Treating Cns Disorders Such As Huntington'S Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.79 Å Release Date: 2014-04-09 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 2Q9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-09
Ligands: 2Q9
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Identification Of Novel Hsp90/Isoform Selective Inhibitors Using Structure-Based Drug Design. Demonstration Of Potential Utility In Treating Cns Disorders Such As Huntington'S Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.86 Å Release Date: 2014-04-09 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: FGH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-09
Ligands: FGH
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Identification Of Novel Hsp90 / Isoform Selective Inhibitors Using Structure-Based Drug Design. Demonstration Of Potential Utility In Treating Cns Disorders Such As Huntington S Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2014-04-09 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 2R6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-09
Ligands: 2R6