Search Count: 46
 |
Crystal Structure Of Ap2 Associated Kinase 1 Complexed With 5-[(4-Aminopiperidin-1-Yl)Methyl]-N-{3-[5-(Propan-2-Yl)-1,3,4-Thiadiazol-2-Yl]Phenyl}Pyrrolo[2,1-F][1,2,4]Triazin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2023-07-12 Classification: TRANSFERASE Ligands: YFV, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-07-12
Ligands: YFV, SO4
 |
Crystal Structure Of Ap2 Associated Kinase 1 Complexed With (5P)-3-({(8R)-5-[(4-Aminopiperidin-1-Yl)Methyl]Pyrrolo[2,1-F][1,2,4]Triazin-4-Yl}Amino)-5-[2-(Propan-2-Yl)-2H-Tetrazol-5-Yl]Phenol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2023-07-12 Classification: TRANSFERASE Ligands: ZRR, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-07-12
Ligands: ZRR, SO4
 |
Crystal Structure Of Rho-Associated Protein Kinase 2 (Rock2) In Complex With 4-(4-(2-(2,3-Dihydro-1H- Indol-1-Yl)-2-Oxoethyl)Phenyl)-1(2H)-Phthalazinone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.71 Å Release Date: 2023-05-10 Classification: TRANSFERASE Ligands: Z8O, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-05-10
Ligands: Z8O, SO4
 |
Crystal Structure Of Glucokinase (Hexokinase 4) Complexed With Ligand Diethyl ({2-[3-(4-Methanesulfonylpheno Xy)-5-{[(2S)-1-Methoxypropan-2-Yl]Oxy}Benzamido]-1,3-Thiaz Ol-4-Yl}Methyl)Phosphonate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2022-03-02 Classification: TRANSFERASE Ligands: GLC, NA, G2T, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-02
Ligands: GLC, NA, G2T, EDO
 |
Crystal Structure Of Glucokinase (Hexokinase 4) Complexed With Ligand Aka Diethyl {[3-(3-{[5-(Azetidine-1-Carbon Yl)Pyrazin-2-Yl]Oxy}-5-(Propan-2-Yloxy)Benzamido)-1H- Pyrazol-1-Yl]Methyl}Phosphonate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2022-03-02 Classification: TRANSFERASE Ligands: G1S, GLC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-02
Ligands: G1S, GLC
 |
Crystal Structure Of Ap2 Associated Kinase 1 Isoform 1 Complexed With Ligand (2R)-2-Amino-N-[3-(Difluorom Ethoxy)-4-(1,3-Oxazol-5-Yl)Phenyl]-4-Methylpentanamide
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.13 Å Release Date: 2022-02-23 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: YFV, SO4, 5OI |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2022-02-23
Ligands: YFV, SO4, 5OI
 |
Crystal Structure Of Ap2 Associated Kinase 1 Isoform 1 Complexed With Ligand 2-(1-Amino-3-Methylbutyl)-6- (Pyridin-4-Yl)Quinoline-4-Carbonitrile
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.12 Å Release Date: 2022-02-23 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 5P6, SO4 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2022-02-23
Ligands: 5P6, SO4
 |
Crystal Structure Of Ap2 Associated Kinase 1 Isoform 1 Complexed With Ligand (2R)-2-Amino-N-[3-(Difluorom Ethoxy)-4-(1,3-Oxazol-5-Yl)Phenyl]-4-Methylpentanamide
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.59 Å Release Date: 2022-02-23 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 5QI, PG6, SO4, YFV |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2022-02-23
Ligands: 5QI, PG6, SO4, YFV
 |
Crystal Structure Of Ap2 Associated Kinase 1 Isoform 1 Complexed With Ligand N-[3-Methoxy-4-(1,3-Oxazol-5-Yl)Phenyl]-3-(Propan-2-Yl)Piperidine-2-Carboxamide
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2021-07-28 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: YFS, SO4, YFV |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2021-07-28
Ligands: YFS, SO4, YFV
 |
Crystal Structure Of Ap2 Associated Kinase 1 Isoform 1 Complexed With Ligand (2R)-2-Amino-N-[3-Methoxy-4- (1,3-Oxazol-5-Yl)Phenyl]-4-Methylpentanamide
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2021-07-28 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: YFY, SO4, YFV |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2021-07-28
Ligands: YFY, SO4, YFV
 |
Crystal Structure Of Hpk1 (Map4K1) Kinase In Complex With 5-{[4-{[(1S)-2-Hydroxy-1-Phenylethyl]Amino}-5-(1,3,4-Oxadiazol-2-Yl)Pyrimidin-2-Yl]Amino}-3,3-Dimethyl-2-Benzofuran-1(3H)-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2021-01-13 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: W9D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-13
Ligands: W9D
 |
Crystal Structure Of Rho-Associated Protein Kinase 2 (Rock2) In Complex With A Potent And Selective Dual Rock Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.21 Å Release Date: 2020-09-02 Classification: TRANSFERASE Ligands: VFA, MES, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-09-02
Ligands: VFA, MES, CL
 |
Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound-6C Aka 6-((1-(4-Cyanopheny L)-2-Oxo-1,2-Dihydro-3-Pyridinyl)Amino)-N-Cyclopropyl-8-(M Ethylamino)Imidazo[1,2-B]Pyridazine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2020-01-29 Classification: TRANSFERASE Ligands: KZJ, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-29
Ligands: KZJ, SO4
 |
Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound_5 Aka 4-[(2-Carbamoylphen Yl)Amino]-6-[(5-Fluoropyridin-2-Yl)Amino]-N-Methylpyridine -3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2019-07-24 Classification: TRANSFERASE Ligands: L8Y, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-24
Ligands: L8Y, SO4
 |
Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound_5 Aka 4-[(2-Carbamoylphen Yl)Amino]-6-[(5-Fluoropyridin-2-Yl)Amino]-N-Methylpyridine -3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.39 Å Release Date: 2019-07-24 Classification: TRANSFERASE Ligands: L91, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-24
Ligands: L91, SO4
 |
Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound_40 Aka 6-Cyclopropaneamido-4-[(2-Methanesulfonylphenyl)Amino]-N-Methylpyridine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.73 Å Release Date: 2019-07-24 Classification: TRANSFERASE Ligands: L9A |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-24
Ligands: L9A
 |
Crystal Structure Of Pi3K Delta In Complex With A Trifluoro-Ethyl-Pyrazol-Pyrolotriazine Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2017-06-07 Classification: TRANSFERASE/TRANSFERASE REGULATOR Ligands: 9EM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-07
Ligands: 9EM
 |
Crystal Structure Of Bruton Agammabulinemia Tyrosine Kinase Complexed With Bms-986142 Aka (2S)-6-Fluoro-5-[3-(8-Fluoro-1-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydroquinazolin-3-Yl)-2-Methylphenyl]-2-(2-Hydroxypropan-2-Yl)-2,3,4,9-Tetrahydro-1H-Carbazole-8-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2017-03-08 Classification: TRANSFERASE Ligands: 73T |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-08
Ligands: 73T
 |
Crystal Structure Of Human Phosphodiesterase 4D In Complex With A Tetrafluoranline Compound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.16 Å Release Date: 2016-12-28 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: ZN, MG, SO4, EOH, 7DJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-12-28
Ligands: ZN, MG, SO4, EOH, 7DJ
 |
Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With 6-[(3,5-Dimethylphe Nyl)Amino]-8- (Methylamino)Imidazo[1,2-B]Pyridazine-3-Carbo Xamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.92 Å Release Date: 2016-12-28 Classification: TRANSFERASE Ligands: 7GL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-12-28
Ligands: 7GL, SO4