Search Count: 40
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Crystal Structure Of Wrn Helicase Domain In Complex With 3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2024-04-24 Classification: HYDROLASE Ligands: ZN, YH8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-04-24
Ligands: ZN, YH8
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Crystal Structure Of Wrn Helicase Domain In Complex With Hro761
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2024-04-24 Classification: HYDROLASE Ligands: ZN, YHC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-04-24
Ligands: ZN, YHC
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Crystal Structure Of Wrn Helicase Domain In Complex With Atpgammas
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2024-04-24 Classification: HYDROLASE Ligands: ZN, AGS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-04-24
Ligands: ZN, AGS
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Mek1 In Complex With Compound 7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.13 Å Release Date: 2022-03-16 Classification: SIGNALING PROTEIN Ligands: 80C, CA, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: 80C, CA, MG
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Crystal Structure Of Dot1L In Complex With An Inhibitor (Compound 3).
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2019-12-11 Classification: TRANSFERASE Ligands: N4W |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-12-11
Ligands: N4W
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Crystal Structure Of Dot1L In Complex With An Inhibitor (Compound 10).
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.19 Å Release Date: 2019-12-11 Classification: TRANSFERASE Ligands: N4Z, K |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-12-11
Ligands: N4Z, K
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Crystal Structure Of Dot1L In Complex With An Inhibitor (Compound 11).
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.21 Å Release Date: 2019-12-11 Classification: TRANSFERASE Ligands: N5K, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-12-11
Ligands: N5K, SO4
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Crystal Structure Of Human Brm In Complex With Compound 16
Organism: Escherichia coli o157:h7, Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.98 Å Release Date: 2018-10-31 Classification: Hydrolase/Hydrolase Inhibitor Ligands: J7J, IPA |
Organism: Escherichia coli o157:h7, Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-10-31
Ligands: J7J, IPA
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Crystal Structure Of Human Brm In Complex With Compound 15
Organism: Escherichia coli o157:h7, Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.84 Å Release Date: 2018-10-31 Classification: Hydrolase/Hydrolase Inhibitor Ligands: J7G, EOH |
Organism: Escherichia coli o157:h7, Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-10-31
Ligands: J7G, EOH
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Crystal Structure Of Dot1L In Complex With Adenosine And Inhibitor Cpd1 [N6-(2,6-Dichlorophenyl)-N6-(Pent-2-Yn-1-Yl)Quinoline-4,6-Diamine]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2017-03-22 Classification: TRANSFERASE Ligands: ADN, 5JJ, TLA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-22
Ligands: ADN, 5JJ, TLA
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Crystal Structure Of Dot1L In Complex With Inhibitor Cpd1 [N6-(2,6-Dichlorophenyl)-N6-(Pent-2-Yn-1-Yl)Quinoline-4,6-Diamine] And Inhibitor Cpd2 [(R)-1-(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)Piperidin-3-Amine]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.09 Å Release Date: 2017-03-22 Classification: TRANSFERASE Ligands: 5JJ, 5JT, TLA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-22
Ligands: 5JJ, 5JT, TLA
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Crystal Structure Of Dot1L In Complex With Inhibitor Cpd7 [N-(3-(((R)-1-(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)Piperidin-3-Yl)(Methyl)Amino)Propyl)-2-(3-(2-Chloro-3-(2-Methylpyridin-3-Yl)Benzo[B]Thiophen-5-Yl)Ureido)Acetamide]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.19 Å Release Date: 2017-03-22 Classification: TRANSFERASE Ligands: 5JU, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-22
Ligands: 5JU, SO4
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Discovery Of Imidazoquinolines As A Novel Class Of Potent, Selective And In Vivo Efficacious Cot Kinase Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2016-08-24 Classification: TRANSFERASE Ligands: 6DA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-08-24
Ligands: 6DA
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Crystal Structure Of Dot1L In Complex With Inhibitor Cpd2 [2-(2-(5-((2-Chlorophenoxy)Methyl)-1H-Tetrazol-1-Yl)Acetyl)-N-(4-Chlorophenyl)Hydrazinecarboxamide]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.69 Å Release Date: 2016-06-15 Classification: TRANSFERASE Ligands: 5EG, K |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-15
Ligands: 5EG, K
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Crystal Structure Of Dot1L In Complex With Inhibitor Cpd3 [N-(1-(2-Chlorophenyl)-1H-Indol-6-Yl)-2-(2-(5-(2-Chlorophenyl)-1H-Tetrazol-1-Yl)Acetyl)Hydrazinecarboxamide]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.41 Å Release Date: 2016-06-15 Classification: TRANSFERASE Ligands: K, 5EK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-15
Ligands: K, 5EK
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Crystal Structure Of Dot1L In Complex With Inhibitor Cpd10 [6'-Chloro-1,4-Dimethyl-5'-(2-Methyl-6-((4-(Methylamino)Pyrimidin-2-Yl)Amino)-1H-Indol-1-Yl)-[3,3'-Bipyridin]-2(1H)-One]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.41 Å Release Date: 2016-06-15 Classification: TRANSFERASE Ligands: K, 5EW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-15
Ligands: K, 5EW
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Crystal Structure Of Dot1L In Complex With Inhibitor Cpd11 [N4-Methyl-N2-(2-Methyl-1-(2-Phenoxyphenyl)-1H-Indol-6-Yl)Pyrimidine-2,4-Diamine]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2016-06-15 Classification: TRANSFERASE Ligands: 5EV, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-15
Ligands: 5EV, SO4
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Crystal Structure Of Dot1L In Complex With Inhibitor Cpd1 [4-(2,6-Dichlorobenzoyl)-N-Methyl-1H-Pyrrole-2-Carboxamide]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2016-06-15 Classification: TRANSFERASE Ligands: 5F4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-15
Ligands: 5F4
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Crystal Structure Of Dot1L In Complex With Inhibitor Cpd3 [(2,6-Dichlorophenyl)(Quinolin-6-Yl)Methanone]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.61 Å Release Date: 2016-06-15 Classification: TRANSFERASE Ligands: 5F6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-15
Ligands: 5F6
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Crystal Structure Of Dot1L In Complex With Inhibitor Cpd5 [N-(2,6-Dichlorophenyl)-4-Methoxy-N-Methylquinolin-6-Amine]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.34 Å Release Date: 2016-06-15 Classification: TRANSFERASE Ligands: 5F7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-15
Ligands: 5F7