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Crystal Structure Of Kirsten Rat Sarcoma G12C Complexed With Gmppnp And Covalently Bound To 1-[(2R,3R)-3-{[(7P)-7-(8-Ethynyl-7-Fluoronaphthalen-1-Yl)-8-Fluoro-2-{ [(2R,4R,7As)-2-Fluorotetrahydro-1H-Pyrrolizin-7A(5H)-Yl]Methoxy}Pyrido[4,3-D] Pyrimidin-4-Yl](Methyl)Amino}-2-Methylpyrrolidin-1-Yl]-3-(Pyrazin-2-Yl)Propan-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.49 Å Release Date: 2026-03-04 Classification: HYDROLASE Ligands: GDP, A1C5K, CA |
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Organism: Paenibacillus
Method: X-RAY DIFFRACTION Resolution:2.04 Å Release Date: 2026-02-18 Classification: HYDROLASE |
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Crystal Structure Of Kirsten Rat Sarcoma G12C Complexed With Gmppnp And Covalently Bound To An Adduct Of {(2S)-4-[7-(8-Chloronaphthalen-1-Yl)-2-{[(2S)-1-Methylpyrrolidin-2-Yl]Methoxy}-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidin-4-Yl]-1-[(2Z)-2-Fluoro-3-(Pyridin-2-Yl)Prop-2-Enoyl]Piperazin-2-Yl}Acetonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.59 Å Release Date: 2025-11-05 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: GNP, A1B7P, MG |
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Crystal Structure Of Kirsten Rat Sarcoma G12C Complexed With Gdp And Covalently Bound To An Adduct Of (2S)-1-{4-[(7P)-7-(8-Ethynyl-7-Fluoro-3-Hydroxynaphthalen-1-Yl)-8-Fluoro-2-{[(2R,4R,7As)-2-Fluorotetrahydro-1H-Pyrrolizin-7A(5H)-Yl]Methoxy}Pyrido[4,3-D]Pyrimidin-4-Yl]Piperazin-1-Yl}-2-Fluoro-3-(1,3-Thiazol-2-Yl)Propan-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2025-11-05 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: GDP, A1B7Q, MG |
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Organism: Homo sapiens, Lama glama
Method: X-RAY DIFFRACTION Resolution:1.73 Å Release Date: 2025-10-29 Classification: PROTEIN TRANSPORT |
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Organism: Escherichia coli
Method: ELECTRON MICROSCOPY Release Date: 2025-01-29 Classification: RIBOSOME |
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Organism: Apis mellifera, Escherichia coli
Method: ELECTRON MICROSCOPY Release Date: 2025-01-29 Classification: RIBOSOME |
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Organism: Escherichia coli
Method: ELECTRON MICROSCOPY Release Date: 2025-01-22 Classification: RIBOSOME |
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Organism: Escherichia coli
Method: ELECTRON MICROSCOPY Release Date: 2025-01-22 Classification: RIBOSOME |
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Organism: Escherichia coli
Method: ELECTRON MICROSCOPY Release Date: 2025-01-22 Classification: RIBOSOME |
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Organism: Escherichia coli
Method: ELECTRON MICROSCOPY Release Date: 2025-01-22 Classification: RIBOSOME |
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Organism: Escherichia coli
Method: ELECTRON MICROSCOPY Release Date: 2025-01-22 Classification: RIBOSOME |
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Organism: Escherichia coli
Method: ELECTRON MICROSCOPY Release Date: 2025-01-22 Classification: RIBOSOME |
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Organism: Escherichia coli
Method: ELECTRON MICROSCOPY Release Date: 2025-01-22 Classification: RIBOSOME |
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Organism: Escherichia coli
Method: ELECTRON MICROSCOPY Release Date: 2025-01-22 Classification: RIBOSOME |
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Organism: Escherichia coli
Method: ELECTRON MICROSCOPY Release Date: 2025-01-22 Classification: RIBOSOME |
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Organism: Escherichia coli
Method: ELECTRON MICROSCOPY Release Date: 2025-01-22 Classification: RIBOSOME |
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Organism: Escherichia coli
Method: ELECTRON MICROSCOPY Release Date: 2025-01-22 Classification: RIBOSOME |
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Organism: Escherichia coli
Method: ELECTRON MICROSCOPY Release Date: 2025-01-22 Classification: RIBOSOME |
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Organism: Escherichia coli
Method: ELECTRON MICROSCOPY Release Date: 2025-01-22 Classification: RIBOSOME |