Search Count: 13
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Jak3 Kinase Domain In Complex With 1-[(3S)-1-Isobutylsulfonyl-3-Piperidyl]-3-(5H-Pyrrolo[2,3-B]Pyrazin-2-Yl)Urea
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2015-05-27 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3C9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-05-27
Ligands: 3C9
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Crystal Structure Of Jak3 Kinase Domain In Complex With A Pyrrolopyrazine-2-Phenyl Ether Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2013-12-11 Classification: TRANSFERASE Ligands: 1NX, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-12-11
Ligands: 1NX, GOL
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Crystal Structure Of Spleen Tyrosine Kinase Complexed With 2-(3,4,5-Trimethoxy-Phenyl)-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxylic Acid Isopropylamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2013-10-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1B4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-10-30
Ligands: 1B4
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Crystal Structure Of Spleen Tyrosine Kinase Complexed With 2-(6-Chloro-1-Methyl-1H-Indazol-3-Yl)-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxylic Acid Isopropylamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2013-10-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1B5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-10-30
Ligands: 1B5
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Crystal Structure Of Spleen Tyrosine Kinase Complexed With 2-(5,6,7,8-Tetrahydro-Imidazo[1,5-A]Pyridin-1-Yl)-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxylic Acid Tert-Butylamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2013-10-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1B6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-10-30
Ligands: 1B6
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Jak3 Kinase Domain In Complex With 2-Phenoxy-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxylic Acid ((S)-1-Cyclopropyl-Ethyl)-Amide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2013-10-16 Classification: Transferase/Transferase Inhibitor Ligands: PHU, 1DT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-10-16
Ligands: PHU, 1DT
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Crystal Structure Of Jak3 Kinase Domain In Complex With An Indazole Substituted Pyrrolopyrazine Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.42 Å Release Date: 2013-09-25 Classification: TRANSFERASE Ligands: VFC, PEG, CL, PG4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: VFC, PEG, CL, PG4
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Crystal Structure Of Spleen Tyrosine Kinase Complexed With R9021
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2013-08-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0XF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-14
Ligands: 0XF
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Crystal Structure Of Spleen Tyrosine Kinase Complexed With 6-((1R,2S)-2-Amino-Cyclohexylamino)-4-(6-Ethyl-Pyridin-2-Ylamino)-Pyridazine-3-Carboxylic Acid Amide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2013-07-10 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0VH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-07-10
Ligands: 0VH
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Jak3 Kinase Domain In Complex With 2-Cyclopropyl-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxylic Acid ((S)-1,2,2-Trimethyl-Propyl)-Amide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2013-01-16 Classification: Transferase/Transferase Inhibitor Ligands: PHU, 933 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-01-16
Ligands: PHU, 933
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Jak3 Kinase Domain In Complex With 2-Cyclopropyl-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxylic Acid ((S)-2-Hydroxy-1,2-Dimethyl-Propyl)-Amide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2013-01-16 Classification: Transferase/Transferase Inhibitor Ligands: 19Q |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-01-16
Ligands: 19Q
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Jak3 Kinase Domain In Complex With 2-Cyclopropyl-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxylic Acid ((R)-2-Hydroxy-1,2-Dimethyl-Propyl
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2013-01-16 Classification: Transferase/Transferase Inhibitor Ligands: 19R |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-01-16
Ligands: 19R
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Jak3 Kinase Domain In Complex With 2-Cyclopropyl-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxylic Acid ((R)-1-Methyl-2-Oxo-2-Piperidin-1-Yl-Ethyl)-Amide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2013-01-16 Classification: Transferase/Transferase Inhibitor Ligands: 19S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-01-16
Ligands: 19S