Search Count: 27
 |
Crystal Structure Of Inhibitor Gne-6893 Bound To Hpk1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2024-10-02 Classification: SIGNALING PROTEIN Ligands: A1APL, DMS, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: A1APL, DMS, NA
 |
Crystal Structure Of Inhibitor 1 Bound To Hpk1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2024-10-02 Classification: SIGNALING PROTEIN Ligands: EDO, A1APO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: EDO, A1APO
 |
Crystal Structure Of Inhibitor Gne-6893 Bound To Hpk1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2024-10-02 Classification: SIGNALING PROTEIN Ligands: MES, EDO, DMS, A1APR, NA, PEG, A1APQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: MES, EDO, DMS, A1APR, NA, PEG, A1APQ
 |
Crystal Structure Of Htdo2 Bound To Inhibitor Gne1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.18 Å Release Date: 2020-05-06 Classification: OXIDOREDUCTASE/Inhibitor Ligands: HEM, QVY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-05-06
Ligands: HEM, QVY
 |
Structure Of The Human Jak1 Kinase Domain With Compound 15
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.64 Å Release Date: 2019-04-24 Classification: IMMUNE SYSTEM Ligands: KEJ, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-24
Ligands: KEJ, GOL
 |
Structure Of The Human Jak1 Kinase Domain With Compound 21
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.83 Å Release Date: 2019-04-24 Classification: IMMUNE SYSTEM Ligands: KEP, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-24
Ligands: KEP, GOL
 |
Structure Of The Human Jak1 Kinase Domain With Compound 20
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2019-04-24 Classification: IMMUNE SYSTEM Ligands: KES, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-24
Ligands: KES, GOL
 |
Structure Of The Human Jak1 Kinase Domain With Compound 39
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.33 Å Release Date: 2019-04-24 Classification: IMMUNE SYSTEM Ligands: GOL, KEV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-24
Ligands: GOL, KEV
 |
Structure Of The Human Jak1 Kinase Domain With Compound 38
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.81 Å Release Date: 2019-04-24 Classification: IMMUNE SYSTEM Ligands: KEY, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-24
Ligands: KEY, GOL
 |
Structure Of The Human Jak1 Kinase Domain With Compound 56
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.69 Å Release Date: 2019-04-24 Classification: IMMUNE SYSTEM Ligands: KF1, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-24
Ligands: KF1, GOL
 |
Structure Of The Human Jak1 Kinase Domain With Compound 54
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2019-04-24 Classification: IMMUNE SYSTEM Ligands: KF4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-24
Ligands: KF4, GOL
 |
The Jak1 Kinase Domain In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2013-05-22 Classification: TRANSFERASE Ligands: C5I, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: C5I, EDO
 |
Jak2 Kinase (Jh1 Domain) In Complex With The Inhibitor Trans-4-[(8As)-2-[(1R)-1-Hydroxyethyl]Imidazo[4,5-D]Pyrrolo[2,3-B]Pyridin-1(8Ah)-Yl]Cyclohexanecarbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1J5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 1J5
 |
Jak1 Kinase (Jh1 Domain) In Complex With The Inhibitor Trans-4-{2-[(1R)-1-Hydroxyethyl]Imidazo[4,5-D]Pyrrolo[2,3-B]Pyridin-1(6H)-Yl}Cyclohexanecarbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1J5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 1J5
 |
Jak1 Kinase (Jh1 Domain) In Complex With The Inhibitor (Trans-4-{2-[(1R)-1-Hydroxyethyl]Imidazo[4,5-D]Pyrrolo[2,3-B]Pyridin-1(6H)-Yl}Cyclohexyl)Acetonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1J6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 1J6
 |
Jak1 Kinase (Jh1 Domain) In Complex With Compound 34
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 15T |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 15T
 |
Jak1 Kinase (Jh1 Domain) In Complex With Compound 72
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2012-11-07 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0UJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-11-07
Ligands: 0UJ
 |
The Jak1 Kinase Domain In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2012-07-04 Classification: Transferase/Transferase Inhibitor Ligands: JAK, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-07-04
Ligands: JAK, EDO
 |
Jak1 Kinase (Jh1 Domain) In Complex With Compound 20
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.22 Å Release Date: 2012-07-04 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0Q2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-07-04
Ligands: 0Q2
 |
Discovery And Optimization Of C-2 Methyl Imidazo-Pyrrolopyridines As Potent And Orally Bioavailable Jak1 Inhibitors With Selectivity Over Jak2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.82 Å Release Date: 2012-07-04 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1RS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-07-04
Ligands: 1RS