Search Count: 17
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Human Sec61 Complex Inhibited By Kzr-261
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2025-07-23 Classification: MEMBRANE PROTEIN Ligands: A1A2B |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2025-07-23
Ligands: A1A2B
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Pre-Clinical Characterization Of Novel Multi-Client Inhibitors Of Sec61 With Broad Anti-Tumor Activity
Organism: Ovis aries
Method: ELECTRON MICROSCOPY Release Date: 2025-07-16 Classification: PROTEIN TRANSPORT Ligands: A1A2B |
Organism: Ovis aries
Method: ELECTRON MICROSCOPY
Release Date: 2025-07-16
Ligands: A1A2B
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Signal Peptide Mimicry Primes Sec61 For Client-Selective Inhibition
Organism: Synthetic construct, Ovis aries
Method: ELECTRON MICROSCOPY Release Date: 2023-03-22 Classification: MEMBRANE PROTEIN |
Organism: Synthetic construct, Ovis aries
Method: ELECTRON MICROSCOPY
Release Date: 2023-03-22
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Crystal Structure Of A Cdk6/Vcyclin Complex With Inhibitor Bound
Organism: Saimiriine herpesvirus 2, Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2014-08-06 Classification: TRANSFERASE/CELL CYCLE/INHIBITOR Ligands: 24V |
Organism: Saimiriine herpesvirus 2, Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-08-06
Ligands: 24V
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Co-Crystal Structure Of Mdm2 (17-111) With Compound 16, {(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-Chlorophenyl)-1-[(1S)-1-(6-Cyclopropylpyridin-2-Yl)Propyl]-3-Methyl-2-Oxopiperidin-3-Yl}Acetic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2014-07-16 Classification: Ligase/Ligase inhibitor Ligands: 35S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-07-16
Ligands: 35S
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Co-Crystal Structure Of Mdm2 With Inhibitor Compound 4
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2014-03-19 Classification: ligase/ligase inhibitor Ligands: 2TW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-03-19
Ligands: 2TW
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Co-Crystal Structure Of Mdm2 With Inhibitor (2S,5R,6S)-2-Benzyl-5,6-Bis(4-Bromophenyl)-4-Methylmorpholin-3-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2013-05-01 Classification: LIGASE/LIGASE INHIBITOR Ligands: 1MN, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-01
Ligands: 1MN, SO4
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Co-Crystal Structure Of Mdm2 With Inhibitor (2S,5R,6S)-2-Benzyl-5,6-Bis(4-Chlorophenyl)-4-Methylmorpholin-3-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2013-05-01 Classification: LIGASE/LIGASE INHIBITOR Ligands: 1MO, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-01
Ligands: 1MO, SO4
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Co-Crystal Structure Of Mdm2 With Inhibitor (2R,3E)-2-[(2S,3R,6S)-2,3-Bis(4-Chlorophenyl)-6-(4-Fluorobenzyl)-5-Oxomorpholin-4-Yl]Pent-3-Enoic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2013-05-01 Classification: LIGASE/LIGASE INHIBITOR Ligands: 1MQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-01
Ligands: 1MQ
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Co-Crystal Structure Of Mdm2 With Inhibitor (2'S,3R,4'S,5'R)-N-(2-Aminoethyl)-6-Chloro-4'-(3-Chloro-2-Fluorophenyl)-2'-(2,2-Dimethylpropyl)-2-Oxo-1,2-Dihydrospiro[Indole-3,3'-Pyrrolidine]-5'-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2013-05-01 Classification: LIGASE/LIGASE INHIBITOR Ligands: 1MT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-01
Ligands: 1MT
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Co-Crystal Structure Of Mdm2 With Inhibitor {(2S,5R,6S)-6-(3-Chlorophenyl)-5-(4-Chlorophenyl)-4-[(2S)-1-Hydroxybutan-2-Yl]-3-Oxomorpholin-2-Yl}Acetic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2013-05-01 Classification: LIGASE/LIGASE INHIBITOR Ligands: 1MY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-01
Ligands: 1MY
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Crystal Structure Of Human 11-Beta-Hydroxysteroid Dehydrogenase 1 (11B-Hsd1) In Complex With 4,4-Disubstituted Cyclohexylbenzamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2011-10-05 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: 3PJ, NAP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-10-05
Ligands: 3PJ, NAP
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Crystal Structure Of 11Beta-Hydroxysteroid Dehydrogenase-1 (11B-Hsd1) In Complex With Diarylsulfone Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2011-07-20 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NAP, 3OQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-07-20
Ligands: NAP, 3OQ
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Crystal Structure Of 11Beta-Hydroxysteroid Dehydrogenase 1 (11B-Hsd1) In Complex With Benzamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2009-12-01 Classification: OXIDOREDUCTASE Ligands: NAP, IIG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-12-01
Ligands: NAP, IIG
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Crystal Structure Of 11B-Hydroxysteroid Dehydrogenase-1 (11B-Hsd1) In Complex With Piperidyl Benzamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2009-06-16 Classification: OXIDOREDUCTASE Ligands: NAP, A49 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-06-16
Ligands: NAP, A49
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Crystal Structure Of Human 11-Beta-Hydroxysteroid Dehydrogenase (Hsd1) In Complex With Sulfonamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2008-07-22 Classification: OXIDOREDUCTASE Ligands: NAP, D4N |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-07-22
Ligands: NAP, D4N
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Crystal Structure Of Human 11-Beta-Hydroxysteroid Dehydrogenase (Hsd1) In Complex With Benzamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2008-07-01 Classification: OXIDOREDUCTASE Ligands: NAP, D3E |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-07-01
Ligands: NAP, D3E