Search Count: 23
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Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.42 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ7
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.91 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ8, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ8, SO4
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ9
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.22 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: Q6K, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: Q6K, SO4
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations. Compound 51 Bound To Egfrinsnpg [V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2025-02-05 Classification: SIGNALING PROTEIN Ligands: A1IUK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-05
Ligands: A1IUK
 |
Optimisation Of Potent, Efficacious, Selective And Blood-Brain Barrier Penetrating Inhibitors Targeting Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2024-11-06 Classification: SIGNALING PROTEIN Ligands: A1H7N, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-11-06
Ligands: A1H7N, IOD
 |
Optimisation Of Potent, Efficacious, Selective And Blood-Brain Barrier Penetrating Inhibitors Targeting Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.02 Å Release Date: 2024-10-16 Classification: SIGNALING PROTEIN Ligands: A1H7O |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-16
Ligands: A1H7O
 |
Mertk Kinase Domain With Type 1.5 Inhibitor Containing A Di-Methyl Pyrazole Group
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.89 Å Release Date: 2021-09-15 Classification: TRANSFERASE Ligands: VJZ, CL, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-09-15
Ligands: VJZ, CL, DMS
 |
Mertk Kinase Domain With Type 1.5 Inhibitor Containing A Di-Methyl, Cyano Pyrazole Group
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.13 Å Release Date: 2021-09-15 Classification: TRANSFERASE Ligands: VK2, CL, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-09-15
Ligands: VK2, CL, DMS
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Mertk Kinase Domain With Type 1.5 Inhibitor Containing A Tri-Methyl Pyrazole Group
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2021-09-15 Classification: TRANSFERASE Ligands: VK5, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-09-15
Ligands: VK5, CL
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Gdc-9545 In Complex With Estrogen Receptor Alpha
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.24 Å Release Date: 2021-06-02 Classification: TRANSCRIPTION Ligands: G9J, ZNM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-06-02
Ligands: G9J, ZNM
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Crystal Structure Of Estrogen Receptor Alpha In Complex With Receptor Degrader 6
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.31 Å Release Date: 2020-07-01 Classification: NUCLEAR PROTEIN Ligands: G9J, U6D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-07-01
Ligands: G9J, U6D
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Structure Of The Human Jak1 Kinase Domain With Compound 15
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.64 Å Release Date: 2019-04-24 Classification: IMMUNE SYSTEM Ligands: KEJ, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-24
Ligands: KEJ, GOL
 |
Structure Of The Human Jak1 Kinase Domain With Compound 21
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.83 Å Release Date: 2019-04-24 Classification: IMMUNE SYSTEM Ligands: KEP, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-24
Ligands: KEP, GOL
 |
Structure Of The Human Jak1 Kinase Domain With Compound 20
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2019-04-24 Classification: IMMUNE SYSTEM Ligands: KES, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-24
Ligands: KES, GOL
 |
Structure Of The Human Jak1 Kinase Domain With Compound 39
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.33 Å Release Date: 2019-04-24 Classification: IMMUNE SYSTEM Ligands: GOL, KEV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-24
Ligands: GOL, KEV
 |
Structure Of The Human Jak1 Kinase Domain With Compound 38
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.81 Å Release Date: 2019-04-24 Classification: IMMUNE SYSTEM Ligands: KEY, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-24
Ligands: KEY, GOL
 |
Structure Of The Human Jak1 Kinase Domain With Compound 56
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.69 Å Release Date: 2019-04-24 Classification: IMMUNE SYSTEM Ligands: KF1, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-24
Ligands: KF1, GOL
 |
Structure Of The Human Jak1 Kinase Domain With Compound 54
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2019-04-24 Classification: IMMUNE SYSTEM Ligands: KF4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-24
Ligands: KF4, GOL
 |
P110Alpha/P85Alpha With Compound 5
Organism: Homo sapiens, Bos taurus
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2016-01-27 Classification: Transferase/Transferase Inhibitor Ligands: 5H2 |
Organism: Homo sapiens, Bos taurus
Method: X-RAY DIFFRACTION
Release Date: 2016-01-27
Ligands: 5H2