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(4~{S},6~{S})-4-[2,4-Bis(Fluoranyl)Phenyl]-4-Methyl-6-Pyrimidin-5-Yl-5,6-Dihydro-1,3-Thiazin-2-Amine (Compound 12) Bound To Bace1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2016-09-07 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 6WD |
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(4~{S},6~{S})-4-[2,4-Bis(Fluoranyl)Phenyl]-6-(3,5-Dimethyl-1,2-Oxazol-4-Yl)-4-Methyl-5,6-Dihydro-1,3-Thiazin-2-Amine (Compound 5) Bound To Bace1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.12 Å Release Date: 2016-09-07 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: IOD, 6WE |
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Crystal Structure Of Beta-Site App-Cleaving Enzyme 1 (Bace-Wt) Complex With Bms-655295 Aka N~3~-((1S,2R)-1- Benzyl-2-Hydroxy-3-((3-Methoxybenzyl)Amino)Propyl)-N~1~, N~1~-Dibutyl-1H-Indole-1,3-Dicarboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2011-04-06 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 3HF, IOD, GOL |
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Crystal Structure Of Beta-Site App-Cleaving Enzyme 1 (Bace-Wt) Complex With Bms-681889 Aka N~1~-Butyl-5-Cyano- N~3~-((1S,2R)-1-(3,5-Difluorobenzyl)-2-Hydroxy-3-((3- Methoxybenzyl)Amino)Propyl)-N~1~-Methyl-1H-Indole-1,3- Dicarboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.01 Å Release Date: 2011-04-06 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 3HH, SO4, GOL |