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Understanding The Role Of Leu22 Variants In Methotrexate Resistance: Comparison Of Wild-Type And Leu22Arg Variant Mouse And Human Dihydrofolate Reductase Ternary Crystal Complexes With Methotrexate And Nadph

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Methotrexate-Resistant Variants Of Human Dihydrofolate Reductase With Substitution Of Leucine 22: Kinetics, Crystallography And Potential As Selectable Markers
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