Search Count: 63
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Crystal Structure Of Compound 16 Bound To Mdm2(17-111), {(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-Chlorophenyl)-1-[(1S)-1-Cyclopropyl-2-(Pyrrolidin-1-Ylsulfonyl)Ethyl]-3-Methyl-2-Oxopiperidin-3-Yl}Acetic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2015-05-06 Classification: Ligase/Ligase inhibitor Ligands: 35T |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-05-06
Ligands: 35T
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Co-Crystal Structure Of Perk Bound To N-{5-[(6,7-Dimethoxyquinolin-4-Yl)Oxy]Pyridin-2-Yl}-1-Methyl-3-Oxo-2-Phenyl-5-(Pyridin-4-Yl)-2,3-Dihydro-1H-Pyrazole-4-Carboxamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2015-02-04 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3Z2, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-02-04
Ligands: 3Z2, SO4
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Co-Crystal Structure Of Perk With 2-Amino-N-[4-Methoxy-3-(Trifluoromethyl)Phenyl]-4-Methyl-3-[2-(Methylamino)Quinazolin-6-Yl]Benzamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2015-01-28 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3Z1, TLA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-28
Ligands: 3Z1, TLA
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Co-Crystal Structure Of Perk Bound To 4-{2-Amino-3-[5-Fluoro-2-(Methylamino)Quinazolin-6-Yl]-4-Methylbenzoyl}-1-Methyl-2,5-Diphenyl-1,2-Dihydro-3H-Pyrazol-3-One Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2015-01-28 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3Z3, TLA, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-28
Ligands: 3Z3, TLA, GOL
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Co-Crystal Structure Of Perk Bound To 4-{2-Amino-4-Methyl-3-[2-(Methylamino)-1,3-Benzothiazol-6-Yl]Benzoyl}-1-Methyl-2,5-Diphenyl-1,2-Dihydro-3H-Pyrazol-3-One Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2015-01-28 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3Z4, TLA, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-28
Ligands: 3Z4, TLA, GOL
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Co-Crystal Structure Of Perk Bound To 4-[2-Amino-4-Methyl-3-(2-Methylquinolin-6-Yl)Benzoyl]-1-Methyl-2,5-Diphenyl-1,2-Dihydro-3H-Pyrazol-3-One Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2015-01-28 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3Z5, TLA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-28
Ligands: 3Z5, TLA
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Co-Crystal Structure Of Perk Bound To 1-[5-(4-Amino-2,7-Dimethyl-7H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)-2,3-Dihydro-1H-Indol-1-Yl]-2-[3-Fluoro-5-(Trifluoromethyl)Phenyl]Ethanone Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2015-01-28 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3Z6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-01-28
Ligands: 3Z6
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Co-Crystal Structure Of Mdm2 In Complex With Am-7209
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.42 Å Release Date: 2014-12-03 Classification: LIGASE/LIGASE INHIBITOR Ligands: 3UD, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-03
Ligands: 3UD, SO4
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Crystal Structure Of Ternary Complex Of Trail, Dr5, And Fab Fragment From A Dr5 Agonist Antibody
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.30 Å Release Date: 2014-09-03 Classification: Apoptosis/Immune System Ligands: ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-09-03
Ligands: ZN
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Co-Crystal Structure Of Mdm2(17-111) In Complex With Compound 48
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2014-04-02 Classification: ligase/ligase inhibitor Ligands: 2TZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-02
Ligands: 2TZ
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Co-Crystal Structure Of Mdm2 With Inhibitor Compound 4
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2014-04-02 Classification: LIGASE/LIGASE INHIBITOR Ligands: 2U0, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-02
Ligands: 2U0, SO4
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Co-Crystal Structure Of Mdm2 With Inhibitor Compound 47
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2014-04-02 Classification: LIGASE/LIGASE INHIBITOR Ligands: 2U1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-02
Ligands: 2U1
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Co-Crystal Structure Of Mdm2 With Inhbitor Compound 3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.38 Å Release Date: 2014-04-02 Classification: LIGASE/LIGASE INHIBITOR Ligands: 2U5, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-02
Ligands: 2U5, SO4
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Co-Crystal Structure Of Mdm2 With Inhbitor Compound 46
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.54 Å Release Date: 2014-04-02 Classification: LIGASE/LIGASE INHIBITOR Ligands: 2U6, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-02
Ligands: 2U6, SO4
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Co-Crystal Structure Of Mdm2 With Inhibitor Compound 49
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2014-04-02 Classification: LIGASE/LIGASE INHIBITOR Ligands: 2U7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-02
Ligands: 2U7
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Co-Crystal Structure Of Mdm2 With Inhibitor Compound 4
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2014-03-19 Classification: ligase/ligase inhibitor Ligands: 2TW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-03-19
Ligands: 2TW
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Co-Crystal Structure Of Mdm2 (17-111) In Complex With Compound 25
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2014-02-19 Classification: ligase/ligase inhibitor Ligands: 2SW, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-02-19
Ligands: 2SW, SO4
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Co-Crystal Structure Of Mdm2 With Inhibitor (2S,5R,6S)-2-Benzyl-5,6-Bis(4-Bromophenyl)-4-Methylmorpholin-3-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2013-05-01 Classification: LIGASE/LIGASE INHIBITOR Ligands: 1MN, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-01
Ligands: 1MN, SO4
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Co-Crystal Structure Of Mdm2 With Inhibitor (2S,5R,6S)-2-Benzyl-5,6-Bis(4-Chlorophenyl)-4-Methylmorpholin-3-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2013-05-01 Classification: LIGASE/LIGASE INHIBITOR Ligands: 1MO, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-01
Ligands: 1MO, SO4
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Co-Crystal Structure Of Mdm2 With Inhibitor (2R,3E)-2-[(2S,3R,6S)-2,3-Bis(4-Chlorophenyl)-6-(4-Fluorobenzyl)-5-Oxomorpholin-4-Yl]Pent-3-Enoic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2013-05-01 Classification: LIGASE/LIGASE INHIBITOR Ligands: 1MQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-01
Ligands: 1MQ