Search Count: 23
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Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound-12 Aka:6-[(Cyclopropanecarbonyl)Amino]-4-{[2-Methoxy-3-(Pyrimidin-2-Yl)Phenyl]Amino}-N-Methylpyridazine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.82 Å Release Date: 2021-08-04 Classification: TRANSFERASE Ligands: VZJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-08-04
Ligands: VZJ
 |
Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound-12 Aka:6-[(Cyclopropanecarbonyl)Amino]-4-({3-[6-(Dimethylcarbamoyl)Pyridazin-3-Yl]-2-Methoxyphenyl}Amino)-N-Methylpyridazine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2021-08-04 Classification: TRANSFERASE Ligands: VZG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-08-04
Ligands: VZG
 |
Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound-6C Aka 6-((1-(4-Cyanopheny L)-2-Oxo-1,2-Dihydro-3-Pyridinyl)Amino)-N-Cyclopropyl-8-(M Ethylamino)Imidazo[1,2-B]Pyridazine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2020-01-29 Classification: TRANSFERASE Ligands: KZJ, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-29
Ligands: KZJ, SO4
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Crystal Structure Of Janus Kinase 2 In Complex With N,N-Dicyclopropyl-10-Ethyl-7-[(3-Methoxypropyl)Amino] -3-Methyl-3,5,8,10-Tetraazatricyclo[7.3.0.0,6] Dodeca-1(9),2(6),4,7,11-Pentaene-11-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.38 Å Release Date: 2015-08-26 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 50Y |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-26
Ligands: 50Y
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Crystal Structure Of Janus Kinase 2 In Complex With N,N-Dicyclopropyl-7-[(Dimethyl-1,3-Thiazol-2-Yl)Amino]-10-Ethyl-3-Methyl-3,5,8,10-Tetraazatricyclo[7.3.0.02,6] Dodeca-1(9),2(6),4,7,11-Pentaene-11-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2015-08-26 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 50W |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-26
Ligands: 50W
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Crystal Structure Of Janus Kinase 2 In Complex With N,N-Dicyclopropyl-10-[(2S)-2,3-Dihydroxypropyl]-3-Methyl-7-(Methylamino)-3,5,8,10-Tetraazatricyclo [7.3.0.02,6]Dodeca-1(9),2(6),4,7,11-Pentaene-11-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2015-08-26 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 50O |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-26
Ligands: 50O
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Crystal Structure Of Janus Kinase 2 In Complex With N,N-Dicyclopropyl-10-Ethyl-7-[(3-Methoxypropyl)Amino] -3-Methyl-3,5,8,10-Tetraazatricyclo[7.3.0.0,6] Dodeca-1(9),2(6),4,7,11-Pentaene-11-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2015-08-26 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 50V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-26
Ligands: 50V
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Crystal Structure Of Janus Kinase 2 In Complex With A 9H-Carbazole-1-Carboxamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2015-06-03 Classification: Transferase/Transferase Inhibitor Ligands: 4OK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-06-03
Ligands: 4OK
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Crystal Structure Of Xiap-Bir2 With A Bound Benzodiazepinone Inhibitor.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2013-11-27 Classification: APOPTOSIS/APOPTOSIS INHIBITOR Ligands: ZN, 1RH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-11-27
Ligands: ZN, 1RH
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Crystal Structure Of Xiap-Bir2 With A Bound Spirocyclic Benzoxazepinone Inhibitor.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2013-11-27 Classification: APOPTOSIS/APOPTOSIS INHIBITOR Ligands: ZN, 1RK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-11-27
Ligands: ZN, 1RK
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Human Bcl-2 With Phenylacylsulfonamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2012-06-06 Classification: APOPTOSIS Ligands: 398 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-06-06
Ligands: 398
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Crystal Structure Of Bcl-Xl Complex With 4-(5-Butyl-3-(Hydroxymethyl)-1-Phenyl-1H-Pyrazol-4-Yl)-3-(3,4-Dihydro-2(1H)-Isoquinolinylcarbonyl)-N-((2-(Trimethylsilyl)Ethyl)Sulfonyl)Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.09 Å Release Date: 2012-06-06 Classification: APOPTOSIS Ligands: 0Q5, IMD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-06-06
Ligands: 0Q5, IMD
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Structure Of Janus Kinase 2 With A Pyrrolotriazine Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2011-02-16 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: J2I |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-02-16
Ligands: J2I
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Crystal Structure Of The Tyrosine Kinase Domain Of The Hepatocyte Growth Factor Receptor C-Met In Complex With A Biarylamine Based Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2010-05-05 Classification: TRANSFERASE Ligands: L8V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-05-05
Ligands: L8V
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Crystal Structure Of The Tyrosine Kinase Domain Of The Hepatocyte Growth Factor Receptor C-Met In Complex With N-(4-(2-Amino-3-Chloropyridin-4-Yloxy)-3-Fluorophenyl)-4-Ethoxy-1-(4-Fluorophenyl)-2-Oxo-1,2-Dihydropyridine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2009-03-31 Classification: TRANSFERASE Ligands: 353 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-03-31
Ligands: 353
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Crystal Structure Of The Tyrosine Kinase Domain Of The Hepatocyte Growth Factor Receptor C-Met In Complex With A Pyrrolopyridinepyridone Based Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2008-08-26 Classification: TRANSFERASE Ligands: 1FN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-08-26
Ligands: 1FN
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Crystal Structure Of The Tyrosine Kinase Domain Of The Hepatocyte Growth Factor Receptor C-Met In Complex With A Aminopyridine Based Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2008-06-10 Classification: TRANSFERASE Ligands: 319 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-06-10
Ligands: 319
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Crystal Structure Of The Tyrosine Kinase Domain Of The Hepatocyte Growth Factor Receptor C-Met In Complex With A Aminopyridine Based Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2008-06-10 Classification: TRANSFERASE Ligands: 320 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-06-10
Ligands: 320
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Crystal Structure Of The Tyrosine Kinase Domain Of The Hepatocyte Growth Factor Receptor C-Met In Complex With A Pyrrolotriazine Based Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2008-03-18 Classification: TRANSFERASE Ligands: CKK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-03-18
Ligands: CKK
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Structure Of Farnesyl Protein Transferase Bound To Pb-93
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION Resolution:2.23 Å Release Date: 2008-03-11 Classification: TRANSFERASE Ligands: ZN, FPP, PB9 |
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION
Release Date: 2008-03-11
Ligands: ZN, FPP, PB9