Search Count: 32
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Crystal Structure Of Ternary Complex Helios-Zf2:Crbn:Ddb1 In Complex With Bms-986449, A Molecular Glue Degrader
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.53 Å Release Date: 2026-09-02 Classification: LIGASE Ligands: ZN, A1CSO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-09-02
Ligands: ZN, A1CSO
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Crystal Structure Of Nedd4 Hect Domain In Complex With Norclomipramine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.12 Å Release Date: 2025-06-04 Classification: LIGASE Ligands: EDO, A1ITH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-06-04
Ligands: EDO, A1ITH
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Crystal Structure Of Nedd4 Hect Domain In Complex With Covalent Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2025-06-04 Classification: LIGASE Ligands: A1ITT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-06-04
Ligands: A1ITT
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Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound-12 Aka:6-[(Cyclopropanecarbonyl)Amino]-4-{[2-Methoxy-3-(Pyrimidin-2-Yl)Phenyl]Amino}-N-Methylpyridazine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.82 Å Release Date: 2021-08-04 Classification: TRANSFERASE Ligands: VZJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-08-04
Ligands: VZJ
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Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound-12 Aka:6-[(Cyclopropanecarbonyl)Amino]-4-({3-[6-(Dimethylcarbamoyl)Pyridazin-3-Yl]-2-Methoxyphenyl}Amino)-N-Methylpyridazine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2021-08-04 Classification: TRANSFERASE Ligands: VZG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-08-04
Ligands: VZG
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Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound-6C Aka 6-((1-(4-Cyanopheny L)-2-Oxo-1,2-Dihydro-3-Pyridinyl)Amino)-N-Cyclopropyl-8-(M Ethylamino)Imidazo[1,2-B]Pyridazine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2020-01-29 Classification: TRANSFERASE Ligands: KZJ, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-29
Ligands: KZJ, SO4
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Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound-11 Aka 6-Cyclopropaneamido-4-{[2-Methoxy-3-(1-Methyl-1H-1,2,4-Tri Azol-3-Yl)Phenyl]Amino}-N-(?H?)Methylpyridazine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2019-07-31 Classification: TRANSFERASE Ligands: LB7, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-31
Ligands: LB7, CL
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Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound_29 Aka 6-[(5-Fluoro-4-Meth Ylpyridin-2-Yl)Amino]-4-({2-Methoxy-3-[(Pyridin-2-Ylmethyl )Carbamoyl]Phenyl}Amino)-N-Methylpyridine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2019-07-31 Classification: TRANSFERASE Ligands: LB4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-31
Ligands: LB4
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Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound_12 Aka 4-[(2-Methanesulfonylphenyl)Amino]-N-(H3)Methyl-6-[(Pyridin-2- Yl)Amino]Pyridazine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.56 Å Release Date: 2019-07-31 Classification: TRANSFERASE Ligands: LAJ, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-31
Ligands: LAJ, SO4
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Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound_5 Aka 4-[(2-Carbamoylphen Yl)Amino]-6-[(5-Fluoropyridin-2-Yl)Amino]-N-Methylpyridine -3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2019-07-24 Classification: TRANSFERASE Ligands: L8Y, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-24
Ligands: L8Y, SO4
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Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound_5 Aka 4-[(2-Carbamoylphen Yl)Amino]-6-[(5-Fluoropyridin-2-Yl)Amino]-N-Methylpyridine -3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.39 Å Release Date: 2019-07-24 Classification: TRANSFERASE Ligands: L91, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-24
Ligands: L91, SO4
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Crystal Structure Of Tyrosine Kinase 2 Jh2 (Pseudo Kinase Domain) Complexed With Compound_40 Aka 6-Cyclopropaneamido-4-[(2-Methanesulfonylphenyl)Amino]-N-Methylpyridine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.73 Å Release Date: 2019-07-24 Classification: TRANSFERASE Ligands: L9A |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-24
Ligands: L9A
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Crystal Structure Of Janus Kinase 2 In Complex With N,N-Dicyclopropyl-10-Ethyl-7-[(3-Methoxypropyl)Amino] -3-Methyl-3,5,8,10-Tetraazatricyclo[7.3.0.0,6] Dodeca-1(9),2(6),4,7,11-Pentaene-11-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.38 Å Release Date: 2015-08-26 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 50Y |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-26
Ligands: 50Y
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Crystal Structure Of Janus Kinase 2 In Complex With N,N-Dicyclopropyl-7-[(Dimethyl-1,3-Thiazol-2-Yl)Amino]-10-Ethyl-3-Methyl-3,5,8,10-Tetraazatricyclo[7.3.0.02,6] Dodeca-1(9),2(6),4,7,11-Pentaene-11-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2015-08-26 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 50W |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-26
Ligands: 50W
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Crystal Structure Of Janus Kinase 2 In Complex With N,N-Dicyclopropyl-10-[(2S)-2,3-Dihydroxypropyl]-3-Methyl-7-(Methylamino)-3,5,8,10-Tetraazatricyclo [7.3.0.02,6]Dodeca-1(9),2(6),4,7,11-Pentaene-11-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2015-08-26 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 50O |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-26
Ligands: 50O
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Crystal Structure Of Janus Kinase 2 In Complex With N,N-Dicyclopropyl-10-Ethyl-7-[(3-Methoxypropyl)Amino] -3-Methyl-3,5,8,10-Tetraazatricyclo[7.3.0.0,6] Dodeca-1(9),2(6),4,7,11-Pentaene-11-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2015-08-26 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 50V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-26
Ligands: 50V
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Crystal Structure Of Janus Kinase 2 In Complex With A 9H-Carbazole-1-Carboxamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2015-06-03 Classification: Transferase/Transferase Inhibitor Ligands: 4OK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-06-03
Ligands: 4OK
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Crystal Structure Of Xiap-Bir2 With A Bound Benzodiazepinone Inhibitor.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2013-11-27 Classification: APOPTOSIS/APOPTOSIS INHIBITOR Ligands: ZN, 1RH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-11-27
Ligands: ZN, 1RH
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Crystal Structure Of Xiap-Bir2 With A Bound Spirocyclic Benzoxazepinone Inhibitor.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2013-11-27 Classification: APOPTOSIS/APOPTOSIS INHIBITOR Ligands: ZN, 1RK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-11-27
Ligands: ZN, 1RK
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Human Bcl-2 With Phenylacylsulfonamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2012-06-06 Classification: APOPTOSIS Ligands: 398 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-06-06
Ligands: 398