Search Count: 13
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Crystal Structure Of An Epoxide Hydrolase Mutant A250Ic/L344V From Aspergillus Usamii E001 At 2.17 Angstroms Resolution
Organism: Aspergillus usamii
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2024-02-07 Classification: HYDROLASE |
Organism: Aspergillus usamii
Method: X-RAY DIFFRACTION
Release Date: 2024-02-07
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Egfr (L858R, T790M, V948R) In Complex With N-{3-[(2-{[4-(4-Methylpiperazin-1-Yl)Phenyl]Amino}-7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)Oxy]Phenyl}Prop-2-Enamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.52 Å Release Date: 2016-02-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 633, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-03
Ligands: 633, SO4, GOL
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Egfr (L858R, T790M, V948R) In Complex With N-[3-({2-[(1-Methyl-1H-Pyrazol-4-Yl)Amino]-7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl}Oxy)Phenyl]Prop-2-Enamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.42 Å Release Date: 2016-02-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 634, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-03
Ligands: 634, SO4, GOL
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Egfr (L858R, T790M, V948R) In Complex With 1-[(3R,4R)-3-[({2-[(1-Methyl-1H-Pyrazol-4-Yl)Amino]-7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl}Oxy)Methyl]-4-(Trifluoromethyl)Pyrrolidin-1-Yl]Prop-2-En-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2016-02-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 63A, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-03
Ligands: 63A, SO4, GOL
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Egfr (L858R, T790M, V948R) In Complex With 1-{(3R,4R)-3-[5-Chloro-2-(1-Methyl-1H-Pyrazol-4-Ylamino)-7H-Pyrrolo[2,3-D]Pyrimidin-4-Yloxymethyl]-4-Methoxy-Pyrrolidin-1-Yl}Propenone (Pf-06459988)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2016-01-27 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 630, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-01-27
Ligands: 630, SO4
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Catalytic Unit Of Pi3Kg In Complex With Pi3K/Mtor Dual Inhibitor Pf-04979064
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2013-11-20 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 19P |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-11-20
Ligands: 19P
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Identification Of Cys 255 In Hif-1 As A Novel Site For Development Of Covalent Inhibitors Of Hif-1 /Arnt Pasb Domain Protein-Protein Interaction.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.52 Å Release Date: 2012-12-05 Classification: TRANSCRIPTION |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-12-05
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Quinazolines With Intra-Molecular Hydrogen Bonding Scaffold (Imhbs) As Pi3K/Mtor Dual Inhibitors.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.91 Å Release Date: 2011-02-09 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3RE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-02-09
Ligands: 3RE
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Quinazolines With Intra-Molecular Hydrogen Bonding Scaffold (Imhbs) As Pi3K/Mtor Dual Inhibitors.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2011-02-09 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3RZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-02-09
Ligands: 3RZ
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Quinazolines With Intra-Molecular Hydrogen Bonding Scaffold (Imhbs) As Pi3K/Mtor Dual Inhibitors.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2011-02-09 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3PS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-02-09
Ligands: 3PS
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4-Methylpteridineones As Orally Active And Selective Pi3K/Mtor Dual Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2010-09-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: OAW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-09-22
Ligands: OAW
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Discovery Of The Highly Potent Pi3K/Mtor Dual Inhibitor Pf-04691502 Through Structure Based Drug Design
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2010-06-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ML8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-06-02
Ligands: ML8
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Discovery Of The Highly Potent Pi3K/Mtor Dual Inhibitor Pf-04691502 Through Structure Based Drug Design
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.55 Å Release Date: 2010-06-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ML9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-06-02
Ligands: ML9