Search Count: 29
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Crystal Structure Of The Catalytic Domain Of Human Pkc Alpha (D463N, V568I, S657E) In Complex With Nvp-Cjl037 At 2.48-A Resolution
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.48 Å Release Date: 2024-01-24 Classification: TRANSFERASE/INHIBITOR Ligands: V5U, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-01-24
Ligands: V5U, MG
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Crystal Structure Of The Catalytic Domain Of Human Pkc Alpha (D463N, V568I, S657E) In Complex With Darovasertib (Nvp-Lxs196) At 2.82-A Resolution
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.82 Å Release Date: 2024-01-24 Classification: TRANSFERASE/INHIBITOR Ligands: W39 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-01-24
Ligands: W39
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Non-Receptor Protein Tyrosine Phosphatase Shp2 In Complex With Allosteric Inhibitor Tno155
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2020-09-23 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: VKS, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-09-23
Ligands: VKS, PO4
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Non-Receptor Protein Tyrosine Phosphatase Shp2 In Complex With Allosteric Inhibitor Compound 24
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.92 Å Release Date: 2020-09-23 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: VKP, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-09-23
Ligands: VKP, PO4
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Non-Receptor Protein Tyrosine Phosphatase Shp2 In Complex With Allosteric Inhibitor Pyrimidinone 7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2019-02-13 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: JE1, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-02-13
Ligands: JE1, PO4
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Non-Receptor Protein Tyrosine Phosphatase Shp2 In Complex With Allosteric Inhibitor Isoxazolo-Pyridinone 3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.12 Å Release Date: 2019-02-13 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: JEJ, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-02-13
Ligands: JEJ, PO4
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Non-Receptor Protein Tyrosine Phosphatase Shp2 In Complex With Allosteric Inhibitor Pyrazolo-Pyridine 4
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.21 Å Release Date: 2019-02-13 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: JED, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-02-13
Ligands: JED, PO4
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Non-Receptor Protein Tyrosine Phosphatase Shp2 In Complex With Allosteric Inhibitor Pyrazolo-Pyrimidinone 5
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.34 Å Release Date: 2019-02-13 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: JE4, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-02-13
Ligands: JE4, PO4
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Non-Receptor Protein Tyrosine Phosphatase Shp2 In Complex With Allosteric Inhibitor Pyrazolo-Pyrimidinone 1 Shp389
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.14 Å Release Date: 2019-02-13 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: JEA, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-02-13
Ligands: JEA, PO4
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Non-Receptor Protein Tyrosine Phosphatase Shp2 In Complex With Allosteric Inhibitor Imidazo-Pyridine 24
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2019-02-13 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: JE7, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-02-13
Ligands: JE7, PO4
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Crystal Structure Of Shp2 E76K Gof Mutant In The Open Conformation
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.62 Å Release Date: 2018-11-07 Classification: HYDROLASE Ligands: GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-11-07
Ligands: GOL
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Crystal Structure Of Shp2 E76K Gof Mutant In Complex With Shp099
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2018-11-07 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 5OD, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-11-07
Ligands: 5OD, SO4, GOL
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Non-Receptor Protein Tyrosine Phosphatase Shp2 In Complex With Allosteric Inhibitor Shp244
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.21 Å Release Date: 2018-01-17 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: DZV, PO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-17
Ligands: DZV, PO4, GOL
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Non-Receptor Protein Tyrosine Phosphatase Shp2 In Complex With Allosteric Inhibitors Shp099 And Shp244
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.12 Å Release Date: 2018-01-17 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 5OD, DZV, PO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-17
Ligands: 5OD, DZV, PO4, GOL
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Non-Receptor Protein Tyrosine Phosphatase Shp2 In Complex With Allosteric Inhibitor Shp504
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2018-01-17 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: DZS, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-17
Ligands: DZS, PO4
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Non-Receptor Protein Tyrosine Phosphatase Shp2 In Complex With Allosteric Inhibitors Shp099 And Shp504
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2018-01-17 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 5OD, DZS, PO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-17
Ligands: 5OD, DZS, PO4, GOL
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Non-Receptor Protein Tyrosine Phosphatase Shp2 In Complex With Allosteric Inhibitor Shp844
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.42 Å Release Date: 2018-01-17 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: DYV, PO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-17
Ligands: DYV, PO4, GOL
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Non-Receptor Protein Tyrosine Phosphatase Shp2 In Complex With Allosteric Inhibitors Shp099 And Shp844
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.09 Å Release Date: 2018-01-17 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 5OD, DYV, PO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-17
Ligands: 5OD, DYV, PO4, GOL
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Non-Receptor Protein Tyrosine Phosphatase Shp2 F285S In Complex With Allosteric Inhibitor Jlr-2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.22 Å Release Date: 2017-12-13 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: DZJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-12-13
Ligands: DZJ
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Ef-Tu (Escherichia Coli) In Complex With Thiomuracin Analog
Organism: Escherichia coli (strain k12), Synthetic construct
Method: X-RAY DIFFRACTION Resolution:2.01 Å Release Date: 2016-07-13 Classification: RNA BINDING PROTEIN/ANTIMICROBIAL Ligands: GDP, MG, SO4 |
Organism: Escherichia coli (strain k12), Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2016-07-13
Ligands: GDP, MG, SO4