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4XU2 image
Mycobacterium Tuberculosis Biotin Ligase Complexed With Bisubstrate Inhibitor 87 With A 3'Deoxy Ribose
Organism: Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION
Resolution:1.85 Å Release Date: 2015-09-02
Classification: LIGASE/LIGASE INHIBITOR
Ligands: 44Q

4XTY image
Mycobacterium Tuberculosis Biotin Ligase Complexed With Bisubstrate Inhibitor 63 With Fluorine In Place Of 2'Oh
Organism: Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION
Resolution:1.80 Å Release Date: 2015-09-02
Classification: LIGASE/LIGASE INHIBITOR
Ligands: 44L

4XTW image
Mycobacterium Tuberculosis Biotin Ligase Complexed With Bisubstrate Inhibitor 46 With Azide In Place Of 2'Oh
Organism: Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION
Resolution:2.30 Å Release Date: 2015-09-02
Classification: LIGASE/LIGASE INHIBITOR
Ligands: 44M, EDO

4XU0 image
Mycobacterium Tuberculosis Biotin Ligase Complexed With Bisubstrate Inhibitor 73 That Has A 2'-Methyl On The Ribose
Organism: Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION
Resolution:1.60 Å Release Date: 2015-09-02
Classification: LIGASE/LIGASE INHIBITOR
Ligands: 44N

4XU3 image
Mycobacterium Tuberculosis Biotin Ligase Complexed With Bisubstrate Inhibitor 90 That Has An Acyclic Ether In Place Of The Ribose
Organism: Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION
Resolution:2.24 Å Release Date: 2015-09-02
Classification: LIGASE/LIGASE INHIBITOR
Ligands: 44R, CL

4XU1 image
Mycobacterium Tuberculosis Biotin Ligase Complexed With Bisubstrate Inhibitor 82 That Incorporates A Morpholine In Place Of The Ribose
Organism: Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION
Resolution:1.70 Å Release Date: 2015-09-02
Classification: LIGASE/LIGASE INHIBITOR
Ligands: 44O, EDO, DMS

4XTX image
Mycobacterium Tuberculosis Biotin Ligase Complexed With Bisubstrate Inhibitor 57 With Azide In Place Of Ribose 2'Oh
Organism: Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION
Resolution:2.30 Å Release Date: 2015-09-02
Classification: LIGASE/LIGASE INHIBITOR
Ligands: 590, EDO

4XTZ image
Mycobacterium Tuberculosis Biotin Ligase Complexed With Bisubstrate Inhibitor 69 That Has A Fluorine In Place Of The Ribose 2'Oh
Organism: Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION
Resolution:1.90 Å Release Date: 2015-09-02
Classification: LIGASE/LIGASE INHIBITOR
Ligands: 594

4XTV image
Mycobacterium Tuberculosis Biotin Ligase Complexed With Bisubstrate Inhibitor 36 (N-({[(1R,3S)-3-(6-Amino-9H-Purin-9-Yl)Cyclopentyl]Methyl}Sulfamoyl)-5-[(3As,4S,6Ar)-2-Oxohexahydro-1H-Thieno[3,4-D]Imidazol-4-Yl]Pentanamide)
Organism: Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION
Resolution:1.45 Å Release Date: 2015-09-02
Classification: LIGASE/LIGASE INHIBITOR
Ligands: 44K

4XTU image
Mycobacterium Tuberculosis Biotin Ligase Complexed With Bisubstrate Inhibitor (N-({[(1R,2S,3R,4R)-4-(6-Amino-9H-Purin-9-Yl)-2,3-Dihydroxycyclopentyl]Methyl}Sulfamoyl)-5-[(3As,4S,6Ar)-2-Oxohexahydro-1H-Thieno[3,4-D]Imidazol-4-Yl]Pentanamide)
Organism: Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION
Resolution:1.65 Å Release Date: 2016-01-13
Classification: LIGASE/LIGASE INHIBITOR
Ligands: 44J

8ENI image
Crystal Structure Of Staphylococcus Aureus Biotin Protein Ligase In Complex With Inhibitor
Organism: Staphylococcus aureus subsp. aureus mu50
Method: X-RAY DIFFRACTION
Resolution:2.40 Å Release Date: 2022-11-30
Classification: LIGASE/LIGASE INHIBITOR
Ligands: WNE

7X09 image
Homo Sapiens Prolyl-Trna Synthetase (Hsprs) In Complex With Inhibitors L95 And Halofuginone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.70 Å Release Date: 2023-08-30
Classification: LIGASE/LIGASE INHIBITOR
Ligands: HFG, JE6, ZN, BR, CA, GOL, CL

4HVC image
Crystal Structure Of Human Prolyl-Trna Synthetase In Complex With Halofuginone And Atp Analogue
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.00 Å Release Date: 2013-01-02
Classification: ligase/ligase inhibitor
Ligands: ANP, HFG, MG, ZN

4GLW image
Dna Ligase A In Complex With Inhibitor
Organism: Streptococcus pneumoniae
Method: X-RAY DIFFRACTION
Resolution:2.00 Å Release Date: 2012-10-10
Classification: LIGASE/LIGASE INHIBITOR
Ligands: SO4, 0XT, NMN

7THQ image
Crystal Structure Of Pltf Trapped With Pigg Using A Proline Adenosine Vinylsulfonamide Inhibitor
Organism: Pseudomonas protegens pf-5, Serratia sp. atcc 39006
Method: X-RAY DIFFRACTION
Resolution:2.46 Å Release Date: 2022-11-30
Classification: LIGASE/LIGASE INHIBITOR
Ligands: AZI, I5M

3RUX image
Crystal Structure Of Biotin-Protein Ligase Bira From Mycobacterium Tuberculosis In Complex With An Acylsulfamide Bisubstrate Inhibitor
Organism: Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION
Resolution:1.70 Å Release Date: 2011-12-14
Classification: LIGASE/LIGASE INHIBITOR
Ligands: BS5

4GLX image
Dna Ligase A In Complex With Inhibitor
Organism: Escherichia coli, Synthetic construct
Method: X-RAY DIFFRACTION
Resolution:1.90 Å Release Date: 2012-10-10
Classification: LIGASE/LIGASE INHIBITOR/DNA
Ligands: ZN, SO4, 0XS

5ICR image
2.25 Angstrom Resolution Crystal Structure Of Fatty-Acid-Coa Ligase (Fadd32) From Mycobacterium Smegmatis In Complex With Inhibitor 5'-O-[(11-Phenoxyundecanoyl)Sulfamoyl]Adenosine.
Organism: Mycobacterium smegmatis (strain atcc 700084 / mc(2)155)
Method: X-RAY DIFFRACTION
Resolution:2.25 Å Release Date: 2016-04-06
Classification: LIGASE/LIGASE INHIBITOR
Ligands: 649, SO4, CL, GOL

6NDL image
Crystal Structure Of Staphylococcus Aureus Biotin Protein Ligase In Complex With A Sulfonamide Inhibitor
Organism: Staphylococcus aureus
Method: X-RAY DIFFRACTION
Resolution:2.00 Å Release Date: 2019-12-18
Classification: LIGASE/LIGASE INHIBITOR
Ligands: GOL, BQX

4XYC image
Nanomolar Inhibitors Of Mycobacterium Tuberculosis Glutamine Synthetase 1: Synthesis, Biological Evaluation And X-Ray Crystallographic Studies
Organism: Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION
Resolution:3.30 Å Release Date: 2015-03-25
Classification: LIGASE/LIGASE INHIBITOR
Ligands: 2K9
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