Search Count: 12
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Pcdhfr-Nadph-270
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION Resolution:1.54 Å Release Date: 2013-05-29 Classification: OXIDOREDUCTASE/Inhibitor Ligands: IXE, NDP |
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: IXE, NDP
 |
Pcdhfr-269 F69N Variant
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2013-05-29 Classification: OXIDOREDUCTASE/Inhibitor Ligands: NDP, IXF |
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: NDP, IXF
 |
Pcdhfr-268-K37S-N69F Variant
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2013-05-15 Classification: OXIDOREDUCTASE/Inhibitor Ligands: NDP, IXG |
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION
Release Date: 2013-05-15
Ligands: NDP, IXG
 |
Design, Synthesis, Biological Evaluation And X-Ray Crystal Structures Of Novel Classical 6,5,6-Tricyclicbenzo[4,5]Thieno[2,3-D]Pyrimidines As Dual Thymidylate Synthase And Dihydrofolate Reductase Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.35 Å Release Date: 2011-05-25 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: 3TZ, NDP, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-05-25
Ligands: 3TZ, NDP, SO4
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Design, Synthesis, Biological Evaluation And X-Ray Crystal Structure Of Novel Classical 6,5,6-Tricyclicbenzo[4,5]Thieno[2,3-D]Pyrimidines As Dual Thymidylate Synthase And Dihydrofolate Reductase Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.35 Å Release Date: 2011-05-25 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NDP, 3TU, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-05-25
Ligands: NDP, 3TU, SO4
 |
Human Dihydrofolate Reductase Q35K Mutant Inhibitor Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.53 Å Release Date: 2009-09-29 Classification: OXIDOREDUCTASE Ligands: GHW, NDP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-09-29
Ligands: GHW, NDP
 |
Design, Synthesis, And X-Ray Crystal Structure Of Classical And Nonclassical 2-Amino-4-Oxo-5-Substituted-6-Thieno[2,3-D]Pyrimidines As Dual Thymidylate Synthase And Dihydrofolate Reductase Inhibitors And As Potential Antitumor Agenst
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.30 Å Release Date: 2009-09-22 Classification: OXIDOREDUCTASE Ligands: GHC, NDP, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-09-22
Ligands: GHC, NDP, SO4
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Human Dihydrofolate Reductase Q35K/N64F Double Mutant Inhibitor Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.30 Å Release Date: 2009-09-22 Classification: OXIDOREDUCTASE Ligands: GHC, NDP, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-09-22
Ligands: GHC, NDP, GOL, SO4
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Human Dihydrofolate Reductase Inhibitor Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.24 Å Release Date: 2009-09-22 Classification: OXIDOREDUCTASE Ligands: GHW, NDP, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-09-22
Ligands: GHW, NDP, SO4
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Human Dihydrofolate Reductase Complexed With Nadph And 2,4-Diamino-5-(1-O-Carboranylmethyl)-6-Methylpyrimidine, A Novel Boron Containing, Nonclassical Antifolate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2007-04-10 Classification: OXIDOREDUCTASE Ligands: NDP, 34B, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-04-10
Ligands: NDP, 34B, GOL
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Human Dihydrofolate Reductase Complexed With Nadph And 2,4-Diamino-5-((7,8-Dicarbaundecaboran-7-Yl)Methyl)-6-Methylpyrimidine, A Novel Boron Containing, Nonclassical Antifolate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2007-04-10 Classification: OXIDOREDUCTASE Ligands: NDP, 39B, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-04-10
Ligands: NDP, 39B, GOL
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Structure-Based Design And Synthesis Of Lipophilic 2,4-Diamino-6-Substituted Quinazolines And Their Evaluation As Inhibitors Of Dihydrofolate Reductase And Potential Antitumor Agents
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 1998-08-12 Classification: OXIDOREDUCTASE Ligands: NDP, PRD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 1998-08-12
Ligands: NDP, PRD