Search Count: 8
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A Novel Oral Selective Estrogen Receptor Down-Regulator, Azd9496, Drives Tumour Growth Inhibition In Estrogen Receptor Positive And Esr1 Mutant Models
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.88 Å Release Date: 2015-12-16 Classification: SIGNALING PROTEIN Ligands: KE9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-12-16
Ligands: KE9
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Optimization Of A Novel Binding Motif To To (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-Fluoro-2-Methylpropyl)-3-Methyl-2,3,4,9-Tetrahydro-1H- Pyrido(3,4-B)Indol-1-Yl)Phenyl)Acrylic Acid (Azd9496), A Potent And Orally Bioavailable Selective Estrogen Receptor Downregulator And Antagonist
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2015-10-14 Classification: SIGNALING PROTEIN Ligands: XBR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-14
Ligands: XBR
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Optimization Of A Novel Binding Motif To To (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-Fluoro-2-Methylpropyl)-3-Methyl-2,3,4,9-Tetrahydro-1H- Pyrido(3,4-B)Indol-1-Yl)Phenyl)Acrylic Acid (Azd9496), A Potent And Orally Bioavailable Selective Estrogen Receptor Downregulator And Antagonist
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2015-10-14 Classification: SIGNALING PROTEIN Ligands: GW5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-14
Ligands: GW5
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Mmp13 In Complex With A Novel Selective Non Zinc Binding Inhibitor Cmpd22
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2011-12-21 Classification: HYDROLASE Ligands: 3W5, HAE, GOL, ZN, CA, NA, 3W4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-12-21
Ligands: 3W5, HAE, GOL, ZN, CA, NA, 3W4
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Mmp13 In Complex With A Novel Selective Non Zinc Binding Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2011-06-29 Classification: HYDROLASE Ligands: 5EL, ZN, CA, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-06-29
Ligands: 5EL, ZN, CA, NA
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Cathepsin L With Az13010160
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.33 Å Release Date: 2009-09-15 Classification: HYDROLASE Ligands: BD3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-09-15
Ligands: BD3
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Crystal Structure Of Cathepsin L In Complex With Az12878478
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.27 Å Release Date: 2009-06-23 Classification: HYDROLASE Ligands: NOW, PG4, ACT, PGE, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-06-23
Ligands: NOW, PG4, ACT, PGE, GOL
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Cdk2 In Complex With An Imidazole Piperazine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2008-08-05 Classification: TRANSFERASE Ligands: IM9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-08-05
Ligands: IM9