Search Count: 31
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Water Network Determines Selectivity For A Series Of Pyrimidone Indoline Amide Pi3Kbeta Inhibitors Over Pi3K-Delta
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.54 Å Release Date: 2015-09-30 Classification: TRANSFERASE Ligands: J82 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2015-09-30
Ligands: J82
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Discovery And Optimization Of Pyrimidone Indoline Amide Pi3Kbeta Inhibitors For The Treatment Of Phosphatase And Tensin Homologue (Pten)-Deficient Cancers
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2014-01-15 Classification: TRANSFERASE Ligands: J82 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2014-01-15
Ligands: J82
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X-Ray Structure Of Pi3K-Gamma Bound To A 4-(Morpholin-4-Yl)- (6-Oxo-1,6-Dihydropyrimidin-2-Yl)Amide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.40 Å Release Date: 2012-11-14 Classification: Transferase/Transferase Inhibitor Ligands: 0W7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-11-14
Ligands: 0W7
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Discovery And Optimization Of New Benzimidazole- And Benzoxazole-Pyrimidone Selective Pi3Kbeta Inhibitors For The Treatment Of Phosphatase And Tensin Homologue (Pten)-Deficient Cancers
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2012-05-16 Classification: TRANSFERASE Ligands: VWN |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2012-05-16
Ligands: VWN
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Naphthalene 1,2-Dioxygenase Rieske Ferredoxin
Organism: Pseudomonas putida
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2008-09-02 Classification: METAL BINDING PROTEIN Ligands: FES |
Organism: Pseudomonas putida
Method: X-RAY DIFFRACTION
Release Date: 2008-09-02
Ligands: FES
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Crystal Structure Of The Highly Amyloidogenic Transthyretin Mutant Ttr G53S/E54D/L55S- Heated Protein
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.29 Å Release Date: 2007-09-04 Classification: TRANSPORT PROTEIN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-09-04
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Structure Of Vaccinia Virus Thymidine Kinase In Complex With Dttp: Insights For Drug Design
Organism: Vaccinia virus
Method: X-RAY DIFFRACTION Resolution:3.10 Å Release Date: 2006-11-13 Classification: TRANSFERASE Ligands: TTP, ZN, MG |
Organism: Vaccinia virus
Method: X-RAY DIFFRACTION
Release Date: 2006-11-13
Ligands: TTP, ZN, MG
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Naphthalene 1,2-Dioxygenase With Nitric Oxide And Indole Bound In The Active Site.
Organism: Pseudomonas putida
Method: X-RAY DIFFRACTION Resolution:1.65 Å Release Date: 2005-02-09 Classification: OXIDOREDUCTASE Ligands: FES, EDO, IND, NO, FE, SO4 |
Organism: Pseudomonas putida
Method: X-RAY DIFFRACTION
Release Date: 2005-02-09
Ligands: FES, EDO, IND, NO, FE, SO4
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Naphthalene 1,2-Dioxygenase With Nitric Oxide Bound In The Active Site.
Organism: Pseudomonas putida
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2005-02-09 Classification: OXIDOREDUCTASE Ligands: FES, NO, FE, SO4 |
Organism: Pseudomonas putida
Method: X-RAY DIFFRACTION
Release Date: 2005-02-09
Ligands: FES, NO, FE, SO4
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Crystal Structure Of Sea Bream Transthyretin In Complex With Thyroxine At 1.9A Resolution
Organism: Sparus aurata
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2004-08-03 Classification: TRANSPORT PROTEIN Ligands: SO4, T44 |
Organism: Sparus aurata
Method: X-RAY DIFFRACTION
Release Date: 2004-08-03
Ligands: SO4, T44
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Crystal Structure Of Sea Bream Transthyretin At 1.90A Resolution
Organism: Sparus aurata
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2004-08-03 Classification: TRANSPORT PROTEIN Ligands: SO4 |
Organism: Sparus aurata
Method: X-RAY DIFFRACTION
Release Date: 2004-08-03
Ligands: SO4
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Crystal Structure Of Sea Bream Transthyretin In Complex With Triiodothyronine At 1.90A Resolution
Organism: Sparus aurata
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2004-08-03 Classification: TRANSPORT PROTEIN Ligands: SO4, T3 |
Organism: Sparus aurata
Method: X-RAY DIFFRACTION
Release Date: 2004-08-03
Ligands: SO4, T3
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Crystal Structure Of Drosophila Deoxyribonucleoside Kinase In Complex With Dttp
Organism: Drosophila melanogaster
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2003-10-23 Classification: TRANSFERASE Ligands: TTP, MG |
Organism: Drosophila melanogaster
Method: X-RAY DIFFRACTION
Release Date: 2003-10-23
Ligands: TTP, MG
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Crystal Structure Of The Transthyretin Mutant Ttr C10A/Y114C
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2003-06-03 Classification: TRANSPORT PROTEIN Ligands: BME |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2003-06-03
Ligands: BME
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Crystal Structure Of Drosophila Deoxyribonucleotide Kinase Complexed With The Substrate Deoxythymidine
Organism: Drosophila melanogaster
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2003-05-27 Classification: TRANSFERASE Ligands: SO4, THM |
Organism: Drosophila melanogaster
Method: X-RAY DIFFRACTION
Release Date: 2003-05-27
Ligands: SO4, THM
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Naphthalene 1,2-Dioxygenase With Naphthalene Bound In The Active Site.
Organism: Pseudomonas putida
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2003-02-20 Classification: OXIDOREDUCTASE Ligands: EDO, NPY, SO4, FES, FE |
Organism: Pseudomonas putida
Method: X-RAY DIFFRACTION
Release Date: 2003-02-20
Ligands: EDO, NPY, SO4, FES, FE
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Naphthalene 1,2-Dioxygenase With Oxidized Rieske Iron Sulphur Center Site.
Organism: Pseudomonas putida
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2003-02-20 Classification: OXIDOREDUCTASE Ligands: EDO, FE, SO4, FES |
Organism: Pseudomonas putida
Method: X-RAY DIFFRACTION
Release Date: 2003-02-20
Ligands: EDO, FE, SO4, FES
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Naphthalene 1,2-Dioxygenase, Binary Complex With Dioxygen
Organism: Pseudomonas putida
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2003-02-20 Classification: OXIDOREDUCTASE Ligands: EDO, OXY, SO4, FES, FE |
Organism: Pseudomonas putida
Method: X-RAY DIFFRACTION
Release Date: 2003-02-20
Ligands: EDO, OXY, SO4, FES, FE
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Naphthalene 1,2-Dioxygenase, Ternary Complex With Dioxygen And Indole
Organism: Pseudomonas putida
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2003-02-20 Classification: OXIDOREDUCTASE Ligands: EDO, IND, OXY, SO4, FES, FE |
Organism: Pseudomonas putida
Method: X-RAY DIFFRACTION
Release Date: 2003-02-20
Ligands: EDO, IND, OXY, SO4, FES, FE
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Naphthalene 1,2-Dioxygenase, Product Complex
Organism: Pseudomonas putida
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2003-02-20 Classification: OXIDOREDUCTASE Ligands: EDO, NDH, SO4, FES, FE |
Organism: Pseudomonas putida
Method: X-RAY DIFFRACTION
Release Date: 2003-02-20
Ligands: EDO, NDH, SO4, FES, FE