Search Count: 47
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Crystal Structure Of C-Met-D1228N In Complex With Kin-7615
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.11 Å Release Date: 2025-04-02 Classification: TRANSFERASE Ligands: A1AB1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-04-02
Ligands: A1AB1
 |
Crystal Structure Of Hpk1 Kinase Domain T165E,S171E Phosphomimetic Mutant In Complex With 3-[6-Chloro-4-(9-Methyl-1-Oxa-4,9-Diazaspiro[5.5]Undec-4-Yl)-7H-Pyrrolo[2,3-D]Pyrimidin-5-Yl]Benzonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.83 Å Release Date: 2023-04-05 Classification: TRANSFERASE Ligands: XXF, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-04-05
Ligands: XXF, SO4
 |
Crystal Structure Of Hpk1 Kinase Domain T165E,S171E Phosphomimetic Mutant In Complex With 3-{4-[(3R,5S)-3-Amino-5-Methylpiperidin-1-Yl]-6-Chloro-7H-Pyrrolo[2,3-D]Pyrimidin-5-Yl}Benzonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2023-04-05 Classification: TRANSFERASE/INHIBITOR Ligands: Y3I |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-04-05
Ligands: Y3I
 |
Crystal Structure Of Hpk1 Kinase Domain T165E,S171E Phosphomimetic Mutant In Complex With 3-{4-[(2S,5R)-5-Amino-2-Methylpiperidin-1-Yl]-6-Chloro-7H-Pyrrolo[2,3-D]Pyrimidin-5-Yl}Benzonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2023-04-05 Classification: TRANSFERASE/INHIBITOR Ligands: Y3O |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-04-05
Ligands: Y3O
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Pkceta Kinase Domain In Complex With Compound 2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2023-04-05 Classification: TRANSFERASE/INHIBITOR Ligands: XXF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-04-05
Ligands: XXF
 |
Pkceta Kinase Domain In Complex With Compound 11
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2023-04-05 Classification: TRANSFERASE/INHIBITOR Ligands: Y3I |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-04-05
Ligands: Y3I
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Crystal Structure Of Pi3Kalpha Selective Inhibitor Pf-06843195
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.41 Å Release Date: 2021-01-06 Classification: SIGNALING PROTEIN, Transferase Ligands: VXY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-06
Ligands: VXY
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Crystal Structure Of Pi3Kalpha Selective Inhibitor 11-1575
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.77 Å Release Date: 2021-01-06 Classification: SIGNALING PROTEIN, Transferase Ligands: VY4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-06
Ligands: VY4
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Crystal Structure Of Pi3Kalpha Inhibitor 10-5429
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.74 Å Release Date: 2021-01-06 Classification: SIGNALING PROTEIN, Transferase Ligands: VY1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-06
Ligands: VY1
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Crystal Structure Of Pi3Kalpha Inhibitor 4-0686
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2021-01-06 Classification: SIGNALING PROTEIN, Transferase Ligands: VYP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-06
Ligands: VYP
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Covalent Complex Of Sars-Cov Main Protease With N-[(2S)-1-({(2S,3S)-3,4-Dihydroxy-1-[(3S)-2-Oxopyrrolidin-3-Yl]Butan-2-Yl}Amino)-4-Methyl-1-Oxopentan-2-Yl]-4-Methoxy-1H-Indole-2-Carboxamide
Organism: Human sars coronavirus
Method: X-RAY DIFFRACTION Resolution:1.47 Å Release Date: 2020-07-08 Classification: VIRAL PROTEIN Ligands: V2M |
Organism: Human sars coronavirus
Method: X-RAY DIFFRACTION
Release Date: 2020-07-08
Ligands: V2M
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Covalent Complex Of Sars-Cov-2 Main Protease With N-[(2S)-1-({(2S,3S)-3,4-Dihydroxy-1-[(3S)-2-Oxopyrrolidin-3-Yl]Butan-2-Yl}Amino)-4-Methyl-1-Oxopentan-2-Yl]-4-Methoxy-1H-Indole-2-Carboxamide
Organism: Severe acute respiratory syndrome coronavirus 2
Method: X-RAY DIFFRACTION Resolution:1.41 Å Release Date: 2020-07-08 Classification: VIRAL PROTEIN Ligands: V2M, EDO |
Organism: Severe acute respiratory syndrome coronavirus 2
Method: X-RAY DIFFRACTION
Release Date: 2020-07-08
Ligands: V2M, EDO
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Covalent Complex Of Sars-Cov Main Protease With 4-Methoxy-N-[(2S)-4-Methyl-1-Oxo-1-({(2S)-3-Oxo-1-[(3S)-2-Oxopyrrolidin-3-Yl]Butan-2-Yl}Amino)Pentan-2-Yl]-1H-Indole-2-Carboxamide
Organism: Human sars coronavirus
Method: X-RAY DIFFRACTION Resolution:1.38 Å Release Date: 2020-07-08 Classification: VIRAL PROTEIN Ligands: V3D, EDO |
Organism: Human sars coronavirus
Method: X-RAY DIFFRACTION
Release Date: 2020-07-08
Ligands: V3D, EDO
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Covalent Complex Of Sars-Cov Main Protease With Ethyl (4R)-4-({N-[(4-Methoxy-1H-Indol-2-Yl)Carbonyl]-L-Leucyl}Amino)-5-[(3S)-2-Oxopyrrolidin-3-Yl]Pentanoate
Organism: Human sars coronavirus
Method: X-RAY DIFFRACTION Resolution:1.45 Å Release Date: 2020-07-08 Classification: VIRAL PROTEIN Ligands: EDO, V34 |
Organism: Human sars coronavirus
Method: X-RAY DIFFRACTION
Release Date: 2020-07-08
Ligands: EDO, V34
 |
Crystal Structure Of The Egfr Kinase Domain (L858R, T790M, V948R) In Complex With A Covalent Inhibitor N-[(3R,4R)-4-Fluoro-1-{6-[(1-Methyl-1H-Pyrazol-4-Yl)Amino]-9-(Propan-2-Yl)-9H-Purin-2-Yl}Pyrrolidin-3-Yl]Propanamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.46 Å Release Date: 2017-03-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 8BP, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-22
Ligands: 8BP, SO4, GOL
 |
Crystal Structure Of The Egfr Kinase Domain (L858R, T790M, V948R) In Complex With A Covalent Inhibitor N-[(3R,4R)-4-Fluoro-1-{6-[(3-Methoxy-1-Methyl-1H-Pyrazol-4-Yl)Amino]-9-(Propan-2-Yl)-9H-Purin-2-Yl}Pyrrolidin-3-Yl]Propanamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.33 Å Release Date: 2017-03-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 8AM, SO4, GOL, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-22
Ligands: 8AM, SO4, GOL, EDO
 |
Crystal Structure Of The Egfr Kinase Domain (L858R, T790M, V948R) In Complex With 4-(4-{[2-{[(3S)-1-Acetylpyrrolidin-3-Yl]Amino}-9-(Propan-2-Yl)-9H-Purin-6-Yl]Amino}Phenyl)-1-Methylpiperazin-1-Ium
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.82 Å Release Date: 2017-03-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 8BM, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-22
Ligands: 8BM, SO4, GOL
 |
Crystal Structure Of The Egfr Kinase Domain In Complex With 4-(4-{[2-{[(3S)-1-Acetylpyrrolidin-3-Yl]Amino}-9-(Propan-2-Yl)-9H-Purin-6-Yl]Amino}Phenyl)-1-Methylpiperazin-1-Ium
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.53 Å Release Date: 2017-03-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 8BM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-22
Ligands: 8BM
 |
Crystal Structure Of The Egfr Kinase Domain (L858R, T790M, V948R) In Complex With A Covalent Inhibitor N-[(3R,4R)-4-Fluoro-1-{6-[(3-Methoxy-1-Methyl-1H-Pyrazol-4-Yl)Amino]-9-Methyl-9H-Purin-2-Yl}Pyrrolidin-3-Yl]Propanamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.58 Å Release Date: 2017-03-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 8BS, SO4, GOL, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-22
Ligands: 8BS, SO4, GOL, EDO
 |
Structure Of Human Anaplastic Lymphoma Kinase In Complex With 2-[(1R)-1-{[2-Amino-5-(1,3-Dimethyl-1H-Pyrazol-4-Yl)Pyridin-3-Yl]Oxy}Ethyl]-4-Fluoro-N,N-Dimethylbenzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2016-08-17 Classification: Transferase/Transferase Inhibitor Ligands: 6YL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-08-17
Ligands: 6YL