Search Count: 8
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Discovery Of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate In Vivo Activity In Mouse Xenograft Models Of Human Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2019-04-17 Classification: APOPTOSIS Ligands: KJP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-17
Ligands: KJP
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Discovery Of Potent 2-Aryl-6,7-Dihydro-5Hpyrrolo[ 1,2-A]Imidazoles As Wdr5 Win-Site Inhibitors Using Fragment-Based Methods And Structure-Based Design
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.83 Å Release Date: 2018-09-05 Classification: dna binding protein/inhibitor |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-05
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Discovery Of Potent 2-Aryl-6,7-Dihydro-5Hpyrrolo[ 1,2-A]Imidazoles As Wdr5 Win-Site Inhibitors Using Fragment-Based Methods And Structure-Based Design
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.63 Å Release Date: 2018-09-05 Classification: dna binding protein/inhibitor Ligands: DMS, G2V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-05
Ligands: DMS, G2V
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Discovery Of Potent 2-Aryl-6,7-Dihydro-5Hpyrrolo[ 1,2-A]Imidazoles As Wdr5 Win-Site Inhibitors Using Fragment-Based Methods And Structure-Based Design
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2018-09-05 Classification: dna binding protein/inhibitor Ligands: G1Y, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-05
Ligands: G1Y, DMS
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Discovery Of Potent 2-Aryl-6,7-Dihydro-5Hpyrrolo[ 1,2-A]Imidazoles As Wdr5 Win-Site Inhibitors Using Fragment-Based Methods And Structure-Based Design
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.88 Å Release Date: 2018-09-05 Classification: dna binding protein/inhibitor Ligands: G2J, SO4, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-05
Ligands: G2J, SO4, DMS
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Discovery Of Potent 2-Aryl-6,7-Dihydro-5Hpyrrolo[ 1,2-A]Imidazoles As Wdr5 Win-Site Inhibitors Using Fragment-Based Methods And Structure-Based Design
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2018-07-18 Classification: dna binding protein/inhibitor Ligands: G2D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-07-18
Ligands: G2D
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Mcl-1 Complexed With Small Molecules
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2018-01-31 Classification: APOPTOSIS Ligands: ECY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-31
Ligands: ECY
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Mcl-1 Complexed With Small Molecules
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2018-01-31 Classification: APOPTOSIS Ligands: ECM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-31
Ligands: ECM