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Search Count: 10

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8CGZ image
Tubulin-Ab8939 Complex
Organism: Rattus norvegicus, Ovis aries
Method: X-RAY DIFFRACTION
Resolution:2.53 Å Release Date: 2024-08-14
Classification: CELL CYCLE
Ligands: GTP, MG, GDP, UIY, SO4

7QJG image
Eed In Complex With Prc2 Allosteric Inhibitor Compound 6
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.80 Å Release Date: 2022-04-13
Classification: TRANSFERASE
Ligands: CL, EKR

7QJU image
Eed In Complex With Prc2 Allosteric Inhibitor Compound 7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.80 Å Release Date: 2022-04-13
Classification: TRANSFERASE
Ligands: CL, EKF

7QK4 image
Eed In Complex With Prc2 Allosteric Inhibitor Compound 22 (Mak683)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.60 Å Release Date: 2022-04-13
Classification: TRANSFERASE
Ligands: CL, EJR

6GGN image
In Vitro And In Vivo Characterization Of A Novel, Highly Potent P53-Mdm2 Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.00 Å Release Date: 2018-09-26
Classification: CELL CYCLE
Ligands: EYH, CL

5OC8 image
Hdm2 (17-111, Wild Type) Complexed With Nvp-Hdm201 At 1.56A
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.56 Å Release Date: 2018-08-22
Classification: LIGASE
Ligands: 9QW, CL

5LN2 image
Discovery Of A Novel Class Of Highly Potent Inhibitors Of The P53-Mdm2 Interaction By Structure-Based Design Starting From A Conformational Argument
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.58 Å Release Date: 2016-09-07
Classification: CELL CYCLE
Ligands: 6ZT, SO4, CL

4ZYF image
Discovery Of Nvp-Cgm097 - A Highly Potent And Selective Mdm2 Inhibitor Undergoing Phase 1 Clinical Trials In P53Wt Tumors: Hdm2 (Mdm2) Complexed With Nvp-Cgm097
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.80 Å Release Date: 2015-07-29
Classification: CELL CYCLE
Ligands: 4T4, CL

4ZYI image
Discovery Of Nvp-Cgm097 - A Highly Potent And Selective Mdm2 Inhibitor Undergoing Phase 1 Clinical Trials In P53Wt Tumors: Hdm2 (Mdm2) Complexed With Cpd2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.67 Å Release Date: 2015-07-29
Classification: CELL CYCLE
Ligands: 4TH, CL

4ZYC image
Discovery Of Dihydroisoquinolinone Derivatives As Novel Inhibitors Of The P53-Mdm2 Interaction With A Distinct Binding Mode: Hdm2 (Mdm2) Complexed With Cpd5
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.95 Å Release Date: 2015-07-22
Classification: LIGASE
Ligands: 4SS, SO4
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