Search Count: 27
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Crystal Structure Of Human Pi3K-Gamma In Complex With (S)-N-(1-(7-Fluoro-2-(Pyridin-2-Yl)Quinolin-3-Yl)Ethyl)-9H-Purin-6-Amine Amg319 Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2014-12-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, 3VC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-17
Ligands: SO4, 3VC
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Crystal Structure Of Human Pi3K-Gamma In Complex With Phenylquinoline Inhibitor N-{(1S)-1-[8-Chloro-2-(3-Fluorophenyl)Quinolin-3-Yl]Ethyl}-9H-Purin-6-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2014-12-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, 3VD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-17
Ligands: SO4, 3VD
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Crystal Structure Of Human Pi3K-Gamma In Complex With Pyridinylquinoline Inhibitor N-{(1S)-1-[8-Chloro-2-(2-Methylpyridin-3-Yl)Quinolin-3-Yl]Ethyl}-9H-Purin-6-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2014-12-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, 3VE, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-17
Ligands: SO4, 3VE, GOL
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Crystal Structure Of Pde10A With 1H-Benzimidazol-2-Yl(4-((3-(Tetrahydro-2H-Pyran-4-Yl)-2-Pyridinyl)Oxy)Phenyl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2014-08-06 Classification: Hydrolase/Hydrolase Inhibitor Ligands: ZN, SO4, 2W1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-08-06
Ligands: ZN, SO4, 2W1
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Crystal Structure Of Human 11-Beta-Hydroxysteroid Dehydrogenase 1 (11B-Hsd1) In Complex With 4,4-Disubstituted Cyclohexylbenzamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2011-10-05 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: 3PJ, NAP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-10-05
Ligands: 3PJ, NAP
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Crystal Structure Of Pka With Compound 36
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2011-01-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: L9L |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-01-19
Ligands: L9L
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Crystal Structure Of Pkab3 (Pka Triple Mutant V123A, L173M, Q181K) With Compound 18
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2011-01-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: L9M |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-01-19
Ligands: L9M
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Crystal Structure Of Pkab3 (Pka Triple Mutant V123A, L173M, Q181K) With Compound 27
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2011-01-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: L9N |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-01-19
Ligands: L9N
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Crystal Structure Of 11Beta-Hydroxysteroid Dehydrogenase 1 (11B-Hsd1) In Complex With Benzamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2009-12-01 Classification: OXIDOREDUCTASE Ligands: NAP, IIG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-12-01
Ligands: NAP, IIG
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Crystal Structure Of Mdm2 With Chromenotriazolopyrimidine 1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2009-11-17 Classification: LIGASE Ligands: YIN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-11-17
Ligands: YIN
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Crystal Structure Of 11B-Hydroxysteroid Dehydrogenase-1 (11B-Hsd1) In Complex With Piperidyl Benzamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2009-06-16 Classification: OXIDOREDUCTASE Ligands: NAP, A49 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-06-16
Ligands: NAP, A49
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Further Studies With The 2-Amino-1,3-Thiazol-4(5H)-One Class Of 11-Hydroxysteroid Dehydrogenase Type 1 (11-Hsd1) Inhibitors: Reducing Pregnane X Receptor (Pxr) Activity And Exploring Activity In A Monkey Pharmacodynamic Model
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2008-11-11 Classification: OXIDOREDUCTASE Ligands: NDP, 352 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-11-11
Ligands: NDP, 352
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Structure Of C-Met With Pyrimidone Inhibitor 7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2008-10-07 Classification: TRANSFERASE Ligands: MT3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-10-07
Ligands: MT3
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Structure Of C-Met With Pyrimidone Inhibitor 50
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2008-10-07 Classification: TRANSFERASE Ligands: MT4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-10-07
Ligands: MT4
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Crystal Structure Of The Vegfr2 Kinase Domain In Complex With A Benzisoxazole Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2008-09-09 Classification: TRANSFERASE Ligands: A96 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-09-09
Ligands: A96
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Crystal Structure Of Human 11-Beta-Hydroxysteroid Dehydrogenase (Hsd1) In Complex With Sulfonamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2008-07-22 Classification: OXIDOREDUCTASE Ligands: NAP, D4N |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-07-22
Ligands: NAP, D4N
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Crystal Structure Of Human 11-Beta-Hydroxysteroid Dehydrogenase (Hsd1) In Complex With Benzamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2008-07-01 Classification: OXIDOREDUCTASE Ligands: NAP, D3E |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-07-01
Ligands: NAP, D3E
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Crystal Structure Of The Vegfr2 Kinase Domain In Complex With A Pyridone Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2008-06-17 Classification: TRANSFERASE Ligands: C19 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-06-17
Ligands: C19
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Crystal Structure Of The Vegfr2 Kinase Domain In Complex With A Bisamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2008-06-17 Classification: TRANSFERASE Ligands: C92 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-06-17
Ligands: C92
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Crystal Structure Of The Vegfr2 Kinase Domain In Complex With A Pyridone Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2008-06-17 Classification: TRANSFERASE Ligands: C52 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-06-17
Ligands: C52