Search Count: 29
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Il-1Beta In Complex With Macrocyclic Peptide Hit
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2024-05-22 Classification: CYTOKINE |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2024-05-22
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Il-1Beta In Complex With Covalent Del Hit
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2024-05-22 Classification: CYTOKINE Ligands: A1H4A |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-05-22
Ligands: A1H4A
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Human Il-1Beta, Unliganded
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.16 Å Release Date: 2024-03-06 Classification: CYTOKINE Ligands: SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-03-06
Ligands: SO4
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Crystal Structure Of Human Il-1Beta In Complex With A Low Molecular Weight Antagonist
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2023-09-13 Classification: CYTOKINE Ligands: T9C |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-09-13
Ligands: T9C
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Crystal Structure Of Human Wdr5 In Complex With Compound Wm662
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.14 Å Release Date: 2023-01-11 Classification: ONCOPROTEIN Ligands: X8N, GOL, SO4, PGE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-01-11
Ligands: X8N, GOL, SO4, PGE
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Complement Factor D In Complex With The Inhibitor (S)-Pyrrolidine-1,2-Dicarboxylic Acid 1-[(1-Methyl-1H-Indol-3-Yl)-Amide] 2-[(3-Trifluoromethoxy-Phenyl)-Amide]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.17 Å Release Date: 2018-03-21 Classification: HYDROLASE Ligands: GOL, 8RT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-21
Ligands: GOL, 8RT
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Complement Factor D In Complex With The Inhibitor (S)-Pyrrolidine-1,2-Dicarboxylic Acid 1-[(1-Carbamoyl-1H-Indol-3-Yl)-Amide] 2-[(3-Trifluoromethoxy-Phenyl)-Amide]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2017-06-28 Classification: HYDROLASE Ligands: SO4, 8RW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-28
Ligands: SO4, 8RW
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Complement Factor D In Complex With The Inhibitor (1R,3S,5R)-2-Aza-Bicyclo[3.1.0]Hexane-2,3-Dicarboxylic Acid 2-[(1-Carbamoyl-1H-Indol-3-Yl)-Amide] 3-[(3-Trifluoromethoxy-Phenyl)-Amide]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.25 Å Release Date: 2017-06-28 Classification: HYDROLASE Ligands: 8RZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-28
Ligands: 8RZ
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Complement Factor D In Complex With The Inhibitor (2S,4S)-4-Amino-Pyrrolidine-1,2-Dicarboxylic Acid 1-[(1-Carbamoyl-1H-Indol-3-Yl)-Amide] 2-[(3-Trifluoromethoxy-Phenyl)-Amide]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2017-06-28 Classification: HYDROLASE Ligands: 8S2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-28
Ligands: 8S2
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Complement Factor D
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.33 Å Release Date: 2017-06-28 Classification: HYDROLASE Ligands: DMS, 8NQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-28
Ligands: DMS, 8NQ
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Complement Factor D In Complex With The Inhibitor (2S,4R)-4-Fluoro-Pyrrolidine-1,2-Dicarboxylic Acid 1-[(1-Carbamoyl-1H-Indol-3-Yl)-Amide] 2-[(3-Trifluoromethoxy-Phenyl)-Amide]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.87 Å Release Date: 2017-06-28 Classification: HYDROLASE Ligands: 8S5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-28
Ligands: 8S5
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Crystal Structure Of Dot1L In Complex With Adenosine And Inhibitor Cpd1 [N6-(2,6-Dichlorophenyl)-N6-(Pent-2-Yn-1-Yl)Quinoline-4,6-Diamine]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2017-03-22 Classification: TRANSFERASE Ligands: ADN, 5JJ, TLA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-22
Ligands: ADN, 5JJ, TLA
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Crystal Structure Of Dot1L In Complex With Inhibitor Cpd1 [N6-(2,6-Dichlorophenyl)-N6-(Pent-2-Yn-1-Yl)Quinoline-4,6-Diamine] And Inhibitor Cpd2 [(R)-1-(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)Piperidin-3-Amine]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.09 Å Release Date: 2017-03-22 Classification: TRANSFERASE Ligands: 5JJ, 5JT, TLA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-22
Ligands: 5JJ, 5JT, TLA
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Crystal Structure Of Dot1L In Complex With Inhibitor Cpd7 [N-(3-(((R)-1-(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)Piperidin-3-Yl)(Methyl)Amino)Propyl)-2-(3-(2-Chloro-3-(2-Methylpyridin-3-Yl)Benzo[B]Thiophen-5-Yl)Ureido)Acetamide]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.19 Å Release Date: 2017-03-22 Classification: TRANSFERASE Ligands: 5JU, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-22
Ligands: 5JU, SO4
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Complement Factor D In Complex With A Reversible Indole Carboxylic Acid Based Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.29 Å Release Date: 2017-02-15 Classification: HYDROLASE Ligands: QJS, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-15
Ligands: QJS, SO4
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Complement Factor D In Complex With A Reversible Benzoic Acid Based Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.65 Å Release Date: 2017-02-15 Classification: HYDROLASE Ligands: M7O |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-15
Ligands: M7O
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Kallikrein-7 In Complex With Compound1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.10 Å Release Date: 2016-10-26 Classification: HYDROLASE Ligands: ACT, 5VT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-10-26
Ligands: ACT, 5VT
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Complement Factor D In Complex With Compound2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.43 Å Release Date: 2016-10-26 Classification: HYDROLASE Ligands: GOL, 5W5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-10-26
Ligands: GOL, 5W5
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Complement Factor D In Complex With Compound 3B
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.47 Å Release Date: 2016-10-26 Classification: HYDROLASE Ligands: GOL, 5WD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-10-26
Ligands: GOL, 5WD
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Complement Factor D In Complex With Compound 5
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.86 Å Release Date: 2016-10-26 Classification: HYDROLASE Ligands: 5WC, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-10-26
Ligands: 5WC, SO4