Search Count: 29
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Discovery Of An Anion-Dependent Farnesyltransferase Inhibitor From A Phenotypic Screen
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION Resolution:2.28 Å Release Date: 2021-09-08 Classification: TRANSFERASE/INHIBITOR Ligands: ACE, 60I, ZN, MG, PPV |
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION
Release Date: 2021-09-08
Ligands: ACE, 60I, ZN, MG, PPV
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Discovery Of An Anion-Dependent Farnesyltransferase Inhibitor From A Phenotypic Screen
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2021-09-08 Classification: TRANSFERASE/INHIBITOR Ligands: ACE, 60I, ZN, MG, DMA |
Organism: Rattus norvegicus
Method: X-RAY DIFFRACTION
Release Date: 2021-09-08
Ligands: ACE, 60I, ZN, MG, DMA
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Structure Of Human Hdac2 In Complex With An Ethyl Ketone Inhibitor Containing A Spiro-Bicyclic Group (Compound 22)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.63 Å Release Date: 2021-08-11 Classification: HYDROLASE Ligands: ZN, SO4, CA, PEG, VJV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-08-11
Ligands: ZN, SO4, CA, PEG, VJV
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Structure Of Human Hdac2 In Complex With Apicidin
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2021-05-05 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, CA, PEG, YED |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-05-05
Ligands: ZN, CA, PEG, YED
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Structure Of Human Hdac2 In Complex With An Inhibitor That Lacks A Zinc Binding Group (Compound 12)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.59 Å Release Date: 2021-05-05 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, CA, ACT, PEG, YEM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-05-05
Ligands: ZN, CA, ACT, PEG, YEM
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Structure Of Human Hdac2 In Complex With An Inhibitor Lacking A Zinc Binding Group (Compound 19)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.49 Å Release Date: 2021-05-05 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, SO4, CA, ACT, PEG, YEV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-05-05
Ligands: ZN, SO4, CA, ACT, PEG, YEV
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Structure Of Human Hdac2 In Complex With A 2-Substituted Benzamide Inhibitor (Compound 20)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.26 Å Release Date: 2020-12-30 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, CA, SO4, PEG, WBA, DMS, WBD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-12-30
Ligands: ZN, CA, SO4, PEG, WBA, DMS, WBD
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Structure Of Human Hdac2 In Complex With A 2-Substituted Benzamide Inhibitor (Compound 16)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.68 Å Release Date: 2020-12-30 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, CA, PEG, WB4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-12-30
Ligands: ZN, CA, PEG, WB4
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Structure Of Human Hdac2 In Complex With An Aryl Ketone Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.56 Å Release Date: 2020-07-29 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, CA, SO4, PEG, V1D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-07-29
Ligands: ZN, CA, SO4, PEG, V1D
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Crystal Structure Of Hiv Protease Complexed With (S)-N-(3-Fluoro-2-(2-(1-(Phenylsulfonyl)Piperazin-2-Yl)Ethyl)Phenyl)-3,3-Bis(4-Fluorophenyl)Propanamide
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION Resolution:1.63 Å Release Date: 2018-01-03 Classification: VIRAL PROTEIN/INHIBITOR Ligands: CL, CKD |
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION
Release Date: 2018-01-03
Ligands: CL, CKD
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Crystal Structure Of Hiv Protease Complexed With N-(3-Fluoro-2-(2-((2S,6R)-6-Methyl-1-(Phenylsulfonyl)Piperazin-2-Yl)Ethyl)Phenyl)-3,3-Bis(4-Fluorophenyl)Propanamide
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION Resolution:1.48 Å Release Date: 2018-01-03 Classification: VIRAL PROTEIN/INHIBITOR Ligands: CL, CKM |
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION
Release Date: 2018-01-03
Ligands: CL, CKM
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Crystal Structure Of Hiv Protease Complexed With N-(3-Fluoro-2-(2-((2S,6R)-6-Methyl-1-(Phenylsulfonyl)Piperazin-2-Yl)Ethyl)Phenyl)-3,3-Bis(4-Fluorophenyl)Propanamide
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2018-01-03 Classification: VIRAL PROTEIN/INHIBITOR Ligands: CL, CKS |
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION
Release Date: 2018-01-03
Ligands: CL, CKS
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Crystal Structure Of Hiv Protease Complexed With N-(3-Fluoro-2-(2-((2S,5S)-5-Methyl-1-(Phenylsulfonyl)Piperazin-2-Yl)Ethyl)Phenyl)-3,3-Bis(4-Fluorophenyl)Propanamide
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION Resolution:1.46 Å Release Date: 2018-01-03 Classification: VIRAL PROTEIN/INHIBITOR Ligands: CL, CKV |
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION
Release Date: 2018-01-03
Ligands: CL, CKV
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Crystal Structure Of Hiv Protease Complexed With N-(3-Fluoro-2-(2-((2S,6S)-6-Methyl-1-(Phenylsulfonyl)Piperazin-2-Yl)Ethyl)Phenyl)-3,3-Bis(4-Fluorophenyl)Propanamide
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2018-01-03 Classification: VIRAL PROTEIN/INHIBITOR Ligands: CL, CKY |
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION
Release Date: 2018-01-03
Ligands: CL, CKY
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Crystal Structure Of Hiv Protease Complexed With N-(2-(2-((6R,9S)-2,2-Dioxido-2-Thia-1,7-Diazabicyclo[4.3.1]Decan-9-Yl)Ethyl)-3-Fluorophenyl)-3,3-Bis(4-Fluorophenyl)Propanamide
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION Resolution:1.62 Å Release Date: 2018-01-03 Classification: VIRAL PROTEIN/INHIBITOR Ligands: CN4, CL |
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION
Release Date: 2018-01-03
Ligands: CN4, CL
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Hcv Ns5B Rna-Dependent Rna Polymerase In Complex With Non-Nucleoside Inhibitor Mk-8876
Organism: Hepatitis c virus genotype 1b (isolate bk)
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2017-08-16 Classification: TRANSFERASE/INHIBITOR Ligands: 9VY |
Organism: Hepatitis c virus genotype 1b (isolate bk)
Method: X-RAY DIFFRACTION
Release Date: 2017-08-16
Ligands: 9VY
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Crystal Structure Of Hiv Protease Complexed With Methyl N-[(1S)-1-Benzhydryl-2-(3-Morpholin-4-Ium-2-Ylpropylamino)-2-Oxo-Ethyl]Carbamate
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION Resolution:1.57 Å Release Date: 2016-05-18 Classification: HYDROLASE/INHIBITOR Ligands: 6EH, CL |
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION
Release Date: 2016-05-18
Ligands: 6EH, CL
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Crystal Structure Of Hiv Protease Complexed With Methyl N-[(1S)-1-[[2-[(3S)-3-[(4-Aminophenyl)Methylamino]-4-Hydroxy-Butyl]Phenyl]Carbamoyl]-2,2-Diphenyl-Ethyl]Carbamate
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2016-05-18 Classification: HYDROLASE/INHIBITOR Ligands: CL, 6EG |
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION
Release Date: 2016-05-18
Ligands: CL, 6EG
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Crystal Structure Of Hiv Protease Complexed With Methyl N-[(1S)-1-Benzhydryl-2-[2-[2-[(2R,5S)-5-(Benzylcarbamoyloxymethyl)Morpholin-2-Yl]Ethyl]Anilino]-2-Oxo-Ethyl]Carbamate
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION Resolution:1.46 Å Release Date: 2016-05-18 Classification: HYDROLASE/INHIBITOR Ligands: CL, 6EF |
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION
Release Date: 2016-05-18
Ligands: CL, 6EF
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Crystal Structure Of Hiv Protease Complexed With [(1S)-1-[(S)-(4-Chlorophenyl)-(3,5-Difluorophenyl)Methyl]-2-[[5-Fluoro-4-[2-[(2R,5S)-5-(2,2,2-Trifluoroethylcarbamoyloxymethyl)Morpholin-4-Ium-2-Yl]Ethyl]Pyridin-1-Ium-3-Yl]Amino]-2-Oxo-Ethyl]Ammonium
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION Resolution:1.15 Å Release Date: 2016-05-18 Classification: HYDROLASE/INHIBITOR Ligands: ACT, 6EE, CL |
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION
Release Date: 2016-05-18
Ligands: ACT, 6EE, CL