Search Count: 24
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Fgfr2 Mutant D650V With Compound 4 (Azd3463)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2026-04-15 Classification: TRANSFERASE Ligands: A1C65, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-04-15
Ligands: A1C65, GOL, SO4
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Fgfr2 Mutant D650V With Compound 6
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2026-04-15 Classification: TRANSFERASE Ligands: A1C66, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-04-15
Ligands: A1C66, GOL, SO4
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Fgfr2 Mutant D650V With Compound 12
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.77 Å Release Date: 2026-04-15 Classification: TRANSFERASE Ligands: A1C67, EDO, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-04-15
Ligands: A1C67, EDO, GOL, SO4
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Tas-120 Covalent Structure With Fgfr2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.98 Å Release Date: 2025-01-01 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: A1AFR, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: A1AFR, GOL, SO4
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Tas-120 Covalent Structure With Fgfr2 Molecular Brake Mutant
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2025-01-01 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: TZ0, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: TZ0, SO4
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Tas-120 Covalent Structure With Fgfr2 Molecular Brake Mutant
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.23 Å Release Date: 2025-01-01 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: TZ0, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: TZ0, SO4
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Tas-120 Covalent Structure With Fgfr2 Molecular Brake Mutant
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.04 Å Release Date: 2025-01-01 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: TZ0, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: TZ0, GOL, SO4
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Fgfr1 Kinase Domain Soak With Inhibitor Tyra-300
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.94 Å Release Date: 2024-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: EDO, A1AV2, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-09-25
Ligands: EDO, A1AV2, SO4
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Fgfr3 Kinase Domain With Inhibitor Tyra-300
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.53 Å Release Date: 2024-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: A1AV2, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-09-25
Ligands: A1AV2, GOL, SO4
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Identification Of Novel, Potent And Selective Gcn2 Inhibitors As First-In-Class Anti-Tumor Agents
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.61 Å Release Date: 2019-10-09 Classification: transferase/transferase inhibitor Ligands: KAV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-10-09
Ligands: KAV
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Identification Of Novel, Potent And Selective Gcn2 Inhibitors As First-In-Class Anti-Tumor Agents
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.01 Å Release Date: 2019-10-09 Classification: transferase/transferase inhibitor Ligands: KA4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-10-09
Ligands: KA4
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Identification Of Novel, Potent And Selective Gcn2 Inhibitors As First-In-Class Anti-Tumor Agents
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2019-10-09 Classification: transferase/transferase inhibitor Ligands: KA7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-10-09
Ligands: KA7
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Structure Of Rorgt In Complex With A Novel Isoquinoline Inverse Agonist.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.18 Å Release Date: 2018-03-21 Classification: transcription/agonist Ligands: MPD, E3S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-21
Ligands: MPD, E3S
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Structure Of Rorgt In Complex With A Novel Inverse Agonist Tak-828.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2018-03-21 Classification: transcription/agonist Ligands: MPD, E3V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-21
Ligands: MPD, E3V
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Discovery Of Clinical Candidate N-{(1S)-1-[3-Fluoro-4-(Trifluoromethoxy)Phenyl]-2-Methoxyethyl}-7-Methoxy-2-Oxo-2,3-Dihydropyrido[2,3-B]Pyrazine-4(1H)-Carboxamide (Tak-915), A Highly Potent, Selective, And Brain-Penetrating Phosphodiesterase 2A Inhibitor For The Treatment Of Cognitive Disorders
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.86 Å Release Date: 2017-12-27 Classification: Hydrolase/Hydrolase Inhibitor Ligands: ZN, MG, 9GA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-12-27
Ligands: ZN, MG, 9GA
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Discovery Of Clinical Candidate N-{(1S)-1-[3-Fluoro-4-(Trifluoromethoxy)Phenyl]-2-Methoxyethyl}-7-Methoxy-2-Oxo-2,3-Dihydropyrido[2,3-B]Pyrazine-4(1H)-Carboxamide (Tak-915), A Highly Potent, Selective, And Brain-Penetrating Phosphodiesterase 2A Inhibitor For The Treatment Of Cognitive Disorders
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2017-08-23 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, MG, 9GJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-08-23
Ligands: ZN, MG, 9GJ
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Design, Synthesis, And Evaluation Of The First Selective And Potent G-Protein-Coupled Receptor Kinase 2 (Grk2) Inhibitor For The Potential Treatment Of Heart Failure
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2017-07-26 Classification: Transferase/Transferase Inhibitor Ligands: QRW, SO4, MES |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-07-26
Ligands: QRW, SO4, MES
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Design, Synthesis, And Evaluation Of The First Selective And Potent G-Protein-Coupled Receptor Kinase 2 (Grk2) Inhibitor For The Potential Treatment Of Heart Failure
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2017-07-26 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 8PV, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-07-26
Ligands: 8PV, SO4
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Discovery Of Tak-659, An Orally Available Investigational Inhibitor Of Spleen Tyrosine Kinase (Syk)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2016-11-30 Classification: Transferase/Transferase Inhibitor Ligands: 7KG, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-30
Ligands: 7KG, EDO
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Discovery Of Tak-659, An Orally Available Investigational Inhibitor Of Spleen Tyrosine Kinase (Syk)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.77 Å Release Date: 2016-11-30 Classification: Transferase/Transferase Inhibitor Ligands: 7KF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-30
Ligands: 7KF