Search Count: 15
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Egfr Exon20 Insertion Mutant Asv Bound With (S)-3-((3-Chloro-2-Methoxyphenyl)Amino)-2-(3-((Tetrahydrofuran-2-Yl)Methoxy)Pyridin-4-Yl)-1,5,6,7-Tetrahydro-4H-Pyrrolo[3,2-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2025-05-14 Classification: ONCOPROTEIN,TRANSFERASE/TRANSFERASE INHIBITOR Ligands: A1IMS, CL, EDO, GOL, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1IMS, CL, EDO, GOL, PEG
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Egfr Exon20 Insertion Mutant Svd Bound With (S)-3-((3-Chloro-2-Methoxyphenyl)Amino)-2-(3-((Tetrahydrofuran-2-Yl)Methoxy)Pyridin-4-Yl)-1,5,6,7-Tetrahydro-4H-Pyrrolo[3,2-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.68 Å Release Date: 2025-05-14 Classification: ONCOPROTEIN,TRANSFERASE/TRANSFERASE INHIBITOR Ligands: A1IMS, EDO, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1IMS, EDO, GOL
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Egfr Exon20 Insertion Mutant Svd Bound With Stx-721
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2025-05-14 Classification: ONCOPROTEIN,TRANSFERASE/TRANSFERASE INHIBITOR Ligands: A1A4E, CL, EDO, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1A4E, CL, EDO, GOL
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Wildtype Egfr Bound With (R)-3-((3-Chloro-2-Methoxyphenyl)Amino)-2-(3-((Tetrahydrofuran-2-Yl)Methoxy)Pyridin-4-Yl)-1,5,6,7-Tetrahydro-4H-Pyrrolo[3,2-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.12 Å Release Date: 2025-05-14 Classification: ONCOPROTEIN Ligands: A1ILZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1ILZ
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Egfr Exon20 Insertion Mutant Npg Bound With (S)-3-((3-Chloro-2-Methoxyphenyl)Amino)-2-(3-((Tetrahydrofuran-2-Yl)Methoxy)Pyridin-4-Yl)-1,5,6,7-Tetrahydro-4H-Pyrrolo[3,2-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.88 Å Release Date: 2025-05-14 Classification: TRANSFERASE Ligands: A1IMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1IMS
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Egfr Exon20 Insertion Mutant Npg Bound With Stx-721
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.63 Å Release Date: 2025-05-14 Classification: TRANSFERASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
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Wild-Type Egfr Bound With Stx-721
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2025-05-14 Classification: TRANSFERASE Ligands: CL, A1IMT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: CL, A1IMT
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Egfr Exon20 Insertion Mutant Npg Bound With Compound 23
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2025-01-29 Classification: TRANSFERASE Ligands: A1IEZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-29
Ligands: A1IEZ
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Egfr Exon20 Insertion Mutant Npg Bound With Compound 39
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2025-01-29 Classification: TRANSFERASE Ligands: EDO, A1IE0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-29
Ligands: EDO, A1IE0
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Wildtype Egfr Bound With Compound 23
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.06 Å Release Date: 2025-01-29 Classification: ONCOPROTEIN Ligands: DTT, A1IEZ, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-29
Ligands: DTT, A1IEZ, CL
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Degrader-Induced Complex Between Ptpn2 And Crbn-Ddb1
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2024-09-11 Classification: HYDROLASE Ligands: WO8, ZN |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2024-09-11
Ligands: WO8, ZN
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Crystal Structure Of Ptpn2 With A Protac
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2024-09-04 Classification: HYDROLASE Ligands: UB0, ACT, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-09-04
Ligands: UB0, ACT, NA
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Crystal Structure Of Mth1 In Complex With Compound 31
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.13 Å Release Date: 2021-11-03 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: ZRP, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-11-03
Ligands: ZRP, SO4
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Crystal Structure Of Mth1 In Complex With Compound 32
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.59 Å Release Date: 2021-11-03 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: ZRV, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-11-03
Ligands: ZRV, SO4
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Phosphoinositide 3-Kinase Gamma Bound To An Pyrrolopyridinone Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.31 Å Release Date: 2018-06-27 Classification: Transferase/Transferase Inhibitor Ligands: EFV, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-06-27
Ligands: EFV, SO4