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4ZPE image
Bace1 In Complex With 4-(Cyclohexylamino)-1-(3-Fluorophenyl)-8-(3-Isopropoxybenzyl)-1,3,8-Triazaspiro[4.5]Dec-3-En-2-One

4ZPF image
Bace1 In Complex With 8-(3-((1-Aminopropan-2-Yl)Oxy)Benzyl)-4-(Cyclohexylamino)-1-(3-Fluorophenyl)-1,3,8-Triazaspiro[4.5]Dec-3-En-2-One

4ZPG image
Bace1 In Complex With 8-Benzyl-4-(Cyclohexylamino)-1-(3-Fluorophenyl)-7-Methyl-1,3,8-Triazaspiro[4.5]Dec-3-En-2-One

3UFL image
Discovery Of Pyrrolidine-Based B-Secretase Inhibitors: Lead Advancement Through Conformational Design For Maintenance Of Ligand Binding Efficiency

3EXO image
Crystal Structure Of Bace1 Bound To Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.10 Å Release Date: 2009-02-03
Classification: HYDROLASE
Ligands: SO4, GOL, 5MS
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