Search Count: 69
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Structure Of Bfl1 In Complex With A Covalent Inhibitor, Alternative Series, Cmpd25
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.43 Å Release Date: 2026-01-14 Classification: APOPTOSIS Ligands: A1JL2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-01-14
Ligands: A1JL2
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Discovery Of A Series Of Covalent, Cell Active Bfl-1 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.49 Å Release Date: 2025-04-16 Classification: APOPTOSIS Ligands: A1H7Q |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-04-16
Ligands: A1H7Q
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Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.42 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ7
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Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.91 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ8, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ8, SO4
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Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ9
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Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.22 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: Q6K, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: Q6K, SO4
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Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations. Compound 51 Bound To Egfrinsnpg [V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2025-02-05 Classification: SIGNALING PROTEIN Ligands: A1IUK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-05
Ligands: A1IUK
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Bfl1 Covalently Bound To Inhibitor Compound 7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.46 Å Release Date: 2024-12-18 Classification: APOPTOSIS Ligands: A1ILY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-18
Ligands: A1ILY
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Bfl1 Covalently Bound To Inhibitor Compound 13
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.42 Å Release Date: 2024-12-18 Classification: APOPTOSIS Ligands: BUD, A1ILV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-18
Ligands: BUD, A1ILV
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Bfl1 Covalently Bound To Inhibitor Compound 39
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.08 Å Release Date: 2024-12-18 Classification: APOPTOSIS Ligands: A1ILX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-18
Ligands: A1ILX
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Bfl1 Covalently Bound To Inhibitor Compound 17
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.39 Å Release Date: 2024-12-18 Classification: APOPTOSIS Ligands: A1ILU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-18
Ligands: A1ILU
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Bfl1 Covalently Bound To Inhibitor Compound 43
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.15 Å Release Date: 2024-12-18 Classification: APOPTOSIS Ligands: A1ILW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-18
Ligands: A1ILW
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Optimisation Of Potent, Efficacious, Selective And Blood-Brain Barrier Penetrating Inhibitors Targeting Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2024-11-06 Classification: SIGNALING PROTEIN Ligands: A1H7N, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-11-06
Ligands: A1H7N, IOD
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Optimisation Of Potent, Efficacious, Selective And Blood-Brain Barrier Penetrating Inhibitors Targeting Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.02 Å Release Date: 2024-10-16 Classification: SIGNALING PROTEIN Ligands: A1H7O |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-16
Ligands: A1H7O
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Discovery Of A Series Of Covalent, Cell Active Bfl-1 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.56 Å Release Date: 2024-10-02 Classification: APOPTOSIS Ligands: A1IDP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: A1IDP
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Discovery Of A Series Of Covalent, Cell Active Bfl-1 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.68 Å Release Date: 2024-10-02 Classification: APOPTOSIS Ligands: A1IDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: A1IDO
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Discovery Of A Series Of Covalent, Cell Active Bfl-1 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2024-10-02 Classification: APOPTOSIS Ligands: A1IDG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: A1IDG
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Bfl1 In Complex With A Reversible Covalent Ligand
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.79 Å Release Date: 2024-07-03 Classification: APOPTOSIS Ligands: A1H2C |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-07-03
Ligands: A1H2C
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 16 Bound To Egfr
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.51 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 2I0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 2I0
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 12 Bound To Egfrinsnpg
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.52 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 2I6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 2I6