Search Count: 33
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Crystal Structure Of Non-Receptor Protein Tyrosine Phosphatase Shp2 In Complex With Inhibitor Compound 7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2024-01-03 Classification: HYDROLASE/INHIBITOR Ligands: W8I |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-01-03
Ligands: W8I
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Crystal Structure Of Non-Receptor Protein Tyrosine Phosphatase Shp2 In Complex With Inhibitor Compound 24
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.06 Å Release Date: 2024-01-03 Classification: HYDROLASE/INHIBITOR Ligands: WAB |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-01-03
Ligands: WAB
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Crystal Structure Of Btk Kinase Domain In Complex With Pirtobrutinib
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2023-03-01 Classification: TRANSFERASE/INHIBITOR Ligands: Y7W, SO4, GOL, BTB |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-03-01
Ligands: Y7W, SO4, GOL, BTB
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Crystal Structure Of Btk C481S Kinase Domain In Complex With Pirtobrutinib
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.33 Å Release Date: 2023-03-01 Classification: TRANSFERASE/INHIBITOR Ligands: Y7W, SO4, GOL, BTB |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-03-01
Ligands: Y7W, SO4, GOL, BTB
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.18 Å Release Date: 2022-04-20 Classification: SIGNALING PROTEIN Ligands: V4T, MG, GDP, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-04-20
Ligands: V4T, MG, GDP, CA
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.38 Å Release Date: 2022-04-20 Classification: SIGNALING PROTEIN Ligands: MG, GDP, V52, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-04-20
Ligands: MG, GDP, V52, CA
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.48 Å Release Date: 2022-04-20 Classification: SIGNALING PROTEIN Ligands: MG, GDP, VLE, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-04-20
Ligands: MG, GDP, VLE, CA
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Identification Of The Clinical Development Candidate Mrtx849, A Covalent Krasg12C Inhibitor For The Treatment Of Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2020-04-22 Classification: HYDROLASE/INHIBITOR Ligands: GDP, MG, M1R |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: GDP, MG, M1R
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Identification Of The Clinical Development Candidate Mrtx849, A Covalent Krasg12C Inhibitor For The Treatment Of Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.03 Å Release Date: 2020-04-22 Classification: HYDROLASE/INHIBITOR Ligands: GDP, MG, QH4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: GDP, MG, QH4
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Identification Of The Clinical Development Candidate Mrtx849, A Covalent Krasg12C Inhibitor For The Treatment Of Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2020-04-22 Classification: HYDROLASE/INHIBITOR Ligands: GDP, MG, M1X |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: GDP, MG, M1X
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.37 Å Release Date: 2020-02-26 Classification: SIGNALING PROTEIN Ligands: MG, GDP, O7K, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-02-26
Ligands: MG, GDP, O7K, SO4
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.72 Å Release Date: 2020-02-19 Classification: SIGNALING PROTEIN Ligands: MG, GDP, MKW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-02-19
Ligands: MG, GDP, MKW
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.31 Å Release Date: 2020-02-19 Classification: SIGNALING PROTEIN Ligands: MG, GDP, MKZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-02-19
Ligands: MG, GDP, MKZ
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Human Erk2 With Erk1/2 Inhibitor, Azd0364.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.33 Å Release Date: 2019-11-20 Classification: TRANSFERASE Ligands: LHZ, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-11-20
Ligands: LHZ, SO4, EDO
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Tetrahydropyridopyrimidines As Covalent Inhibitors Of Kras-G12C
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2018-12-12 Classification: ONCOPROTEIN Ligands: GDP, MG, K9M |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-12-12
Ligands: GDP, MG, K9M
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Tetrahydropyridopyrimidines As Covalent Inhibitors Of Kras-G12C
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.72 Å Release Date: 2018-12-12 Classification: ONCOPROTEIN Ligands: GDP, MG, K9J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-12-12
Ligands: GDP, MG, K9J
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Human Erk2 With An Erk1/2 Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.74 Å Release Date: 2017-04-19 Classification: TRANSFERASE Ligands: SO4, 8X2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-04-19
Ligands: SO4, 8X2
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Human Erk2 With An Erk1/2 Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.14 Å Release Date: 2017-04-19 Classification: TRANSFERASE Ligands: SO4, 8X5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-04-19
Ligands: SO4, 8X5
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Human Erk2 With An Erk1/2 Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2017-04-19 Classification: TRANSFERASE Ligands: SO4, 8XH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-04-19
Ligands: SO4, 8XH
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Human Erk2 With An Erk1/2 Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.12 Å Release Date: 2017-04-19 Classification: TRANSFERASE Ligands: SO4, 8XE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-04-19
Ligands: SO4, 8XE