Search Count: 12
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Structure-Guided Optimization Of A Novel Class Of Ask1 Inhibitors With Increased Sp3 Character And An Exquisite Selectivity Profile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2020-08-12 Classification: METAL BINDING PROTEIN Ligands: V3S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-12
Ligands: V3S
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Structure-Based Design Of Ask1 Inhibitors As Potential First-In-Class Agents For Heart Failure
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2017-06-07 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, 8GV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-07
Ligands: SO4, 8GV
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Structure-Based Design Of Ask1 Inhibitors As Potential First-In-Class Agents For Heart Failure
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2017-06-07 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 8GY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-07
Ligands: 8GY
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Structure-Based Design Of Ask1 Inhibitors As Potential First-In-Class Agents For Heart Failure
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.95 Å Release Date: 2017-06-07 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 8GS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-07
Ligands: 8GS
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Human Glucokinase In Complex With Novel Indazole Activator.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.39 Å Release Date: 2017-05-31 Classification: transferase/transferase activator Ligands: GLC, 8WM, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-31
Ligands: GLC, 8WM, IOD
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Human Glucokinase In Complex With Novel Pyrazole Activator.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.08 Å Release Date: 2017-05-31 Classification: transferase/transferase activator Ligands: GLC, 8WJ, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-31
Ligands: GLC, 8WJ, IOD
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Structure-Based Drug Design Of Novel Ask1 Inhibitors Using A Fully Integrated Lead Optimization Strategy
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.10 Å Release Date: 2017-03-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 8V4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-29
Ligands: 8V4
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Structure-Based Drug Design Of Novel Ask1 Inhibitors Using A Fully Integrated Lead Optimization Strategy
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2017-03-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 8V7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-29
Ligands: 8V7
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Structure-Based Optimization Of 1H-Imidazole-2-Carboxamides As Axl Kinase Inhibitors Utilizing A Mer Mutant Surrogate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.24 Å Release Date: 2017-01-25 Classification: Transferase/Transferase Inhibitor Ligands: 79Y |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-01-25
Ligands: 79Y
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Structure-Based Optimization Of 1H-Imidazole-2-Carboxamides As Axl Kinase Inhibitors Utilizing A Mer Mutant Surrogate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.68 Å Release Date: 2017-01-25 Classification: Transferase/Transferase Inhibitor Ligands: 7AE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-01-25
Ligands: 7AE
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Crystal Structure Of The Human Mitogen-Activated Protein Kinase Kinase 1 (Mek 1) In Complex With Ligand And Mgatp
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2011-02-23 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ATP, MG, IZG, ACT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-02-23
Ligands: ATP, MG, IZG, ACT
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Crystal Structure Of The Human Mitogen-Activated Protein Kinase Kinase 1 (Mek 1) In Complex With Ligand And Mgadp
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2010-07-28 Classification: TRANSFERASE Ligands: ADP, MG, LSG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-07-28
Ligands: ADP, MG, LSG