Search Count: 16
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Kras G13D Mutant In Complex With Gdp And Compound 6.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2026-06-03 Classification: ONCOPROTEIN Ligands: A1C3J, GDP, MG, PO4 |
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Kras G12V Mutant In Complex With Gdp And Compound 12.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.68 Å Release Date: 2026-06-03 Classification: ONCOPROTEIN Ligands: MG, A1C3N, GDP, SO4 |
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Kras G12V Mutant In Complex With Gdp And Compound 8.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.91 Å Release Date: 2026-06-03 Classification: ONCOPROTEIN Ligands: MG, A1C3O, GDP |
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Crystal Structure Of Sos1 With Mrtx0902, A Potent And Selective Inhibitor Of The Sos1:Kras Protein-Protein Interaction
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2022-07-27 Classification: SIGNALING PROTEIN/INHIBITOR Ligands: NKF |
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Crystal Structure Of Sos1 With Phthalazine Inhibitor Bound (Compound 15)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.29 Å Release Date: 2022-07-27 Classification: SIGNALING PROTEIN/INHIBITOR Ligands: NL0 |
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Lon Protease Proteolytic Domain
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.23 Å Release Date: 2021-04-14 Classification: HYDROLASE Ligands: SO4 |
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Lon Protease Proteolytic Domain
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.51 Å Release Date: 2021-04-14 Classification: HYDROLASE Ligands: UFY, SO4 |
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Lon Protease Proteolytic Domain Complexed With Covalent Boronic Acid Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.51 Å Release Date: 2021-04-14 Classification: HYDROLASE Ligands: UKS |
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Lon Protease Proteolytic Domain Complexed With Bortezomib
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.12 Å Release Date: 2021-04-14 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: BO2, 1PE, GOL |
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Braf In Complex With N-(4-Methyl-3-(1-Methyl-2-Oxo-2,3-Dihydro-1H-Benzo[D]Imidazol-5-Yl)Phenyl)-3-(Trifluoromethyl)Benzamide.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.04 Å Release Date: 2019-10-23 Classification: transferase/transferase inhibitor Ligands: K7S |
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Braf In Complex With N-(3-(2-(2-Hydroxyethoxy)-6-Morpholinopyridin-4-Yl)-4-Methylphenyl)-2-(Trifluoromethyl)Isonicotinamide (Lxh254)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.37 Å Release Date: 2019-09-04 Classification: transferase/transferase inhibitor Ligands: K81 |
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Braf In Complex With N-(3-(Tert-Butyl)Phenyl)-4-Methyl-3-(6-Morpholinopyrimidin-4-Yl)Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.26 Å Release Date: 2017-06-28 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 92D |
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Braf In Complex With Raf709
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2017-06-28 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 92J |
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Crystal Structure Of The Braf:Mek1 Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.85 Å Release Date: 2014-06-18 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ACP, MG, 573, CL |
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Crystal Structure Of Braf-V600E Bound To Gdc0879
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2014-06-18 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 29L, CL |
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Crystal Structure Of Mek1 Kinase Bound To Gdc0973
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2013-08-07 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ANP, MG, EUI |