Search Count: 24
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Optimisation Of Potent, Efficacious, Selective And Blood-Brain Barrier Penetrating Inhibitors Targeting Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2024-11-06 Classification: SIGNALING PROTEIN Ligands: A1H7N, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-11-06
Ligands: A1H7N, IOD
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Optimisation Of Potent, Efficacious, Selective And Blood-Brain Barrier Penetrating Inhibitors Targeting Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.02 Å Release Date: 2024-10-16 Classification: SIGNALING PROTEIN Ligands: A1H7O |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-16
Ligands: A1H7O
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Discovery Of A Series Of Covalent, Cell Active Bfl-1 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.56 Å Release Date: 2024-10-02 Classification: APOPTOSIS Ligands: A1IDP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: A1IDP
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Discovery Of A Series Of Covalent, Cell Active Bfl-1 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.68 Å Release Date: 2024-10-02 Classification: APOPTOSIS Ligands: A1IDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: A1IDO
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Discovery Of A Series Of Covalent, Cell Active Bfl-1 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2024-10-02 Classification: APOPTOSIS Ligands: A1IDG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: A1IDG
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Human Prmt5 In Complex With Az Compound 1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2024-08-14 Classification: TRANSFERASE Ligands: A1H8A, MTA, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-08-14
Ligands: A1H8A, MTA, SO4
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Human Prmt5 In Complex With Az Compound 12
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2024-08-14 Classification: TRANSFERASE Ligands: A1H76, MTA, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-08-14
Ligands: A1H76, MTA, SO4
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Human Prmt5 In Complex With Az Compound 21
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2024-08-14 Classification: TRANSFERASE Ligands: A1H8B, MTA, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-08-14
Ligands: A1H8B, MTA, SO4
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Human Prmt5 In Complex With Az Compound 28
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2024-08-14 Classification: TRANSFERASE Ligands: A1H73, MTA, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-08-14
Ligands: A1H73, MTA, SO4
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Bfl1 In Complex With A Reversible Covalent Ligand
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.79 Å Release Date: 2024-07-03 Classification: APOPTOSIS Ligands: A1H2C |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-07-03
Ligands: A1H2C
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 16 Bound To Egfr
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.51 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 2I0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 2I0
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 12 Bound To Egfrinsnpg
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.52 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 2I6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 2I6
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 22 Bound To Egfrinsnpg [V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 2EI, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 2EI, IOD
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 33 Bound To Egfrinsnpg [V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.28 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 26X |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 26X
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 18 Bound To Egfr[V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.13 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 2II |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 2II
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 33 Bound To Egfr[V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.62 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 26X, ATP, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 26X, ATP, MG
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2023-07-12 Classification: SIGNALING PROTEIN Ligands: MG, GDP, PQI |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-07-12
Ligands: MG, GDP, PQI
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.11 Å Release Date: 2023-07-12 Classification: SIGNALING PROTEIN Ligands: MG, GDP, PUO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-07-12
Ligands: MG, GDP, PUO
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Crystal Structure Of The Bromodomain Of Atad2 With Az13824374
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2022-01-19 Classification: GENE REGULATION Ligands: SO4, 96L |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-19
Ligands: SO4, 96L
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Crystal Structure Of The Bromodomain Of Atad2 With Phenol Hts Hit (Cpd 6)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2022-01-19 Classification: GENE REGULATION Ligands: SO4, 963 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-19
Ligands: SO4, 963