Search Count: 44
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Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.42 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ7
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.91 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ8, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ8, SO4
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: A1IZ9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: A1IZ9
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.22 Å Release Date: 2025-02-12 Classification: SIGNALING PROTEIN Ligands: Q6K, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: Q6K, SO4
 |
Highly Optimized Cns Penetrant Inhibitors Of Egfr Exon20 Insertion Mutations. Compound 51 Bound To Egfrinsnpg [V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2025-02-05 Classification: SIGNALING PROTEIN Ligands: A1IUK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-05
Ligands: A1IUK
 |
Optimisation Of Potent, Efficacious, Selective And Blood-Brain Barrier Penetrating Inhibitors Targeting Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2024-11-06 Classification: SIGNALING PROTEIN Ligands: A1H7N, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-11-06
Ligands: A1H7N, IOD
 |
Optimisation Of Potent, Efficacious, Selective And Blood-Brain Barrier Penetrating Inhibitors Targeting Egfr Exon20 Insertion Mutations
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.02 Å Release Date: 2024-10-16 Classification: SIGNALING PROTEIN Ligands: A1H7O |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-16
Ligands: A1H7O
 |
Estrogen Receptor Alpha In Complex With Compound 29
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.68 Å Release Date: 2023-02-01 Classification: TRANSCRIPTION Ligands: H09 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-02-01
Ligands: H09
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Oestrogen Receptor Ligand Binding Domain In Complex With Compound 38
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2023-02-01 Classification: GENE REGULATION Ligands: GZI |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-02-01
Ligands: GZI
 |
Eed In Complex With A Cyano-Benzofuran
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.26 Å Release Date: 2021-05-12 Classification: PROTEIN BINDING Ligands: CA, L9W, PV5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-05-12
Ligands: CA, L9W, PV5
 |
Eed In Complex With A Triazolopyrimidine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2021-05-12 Classification: PROTEIN BINDING Ligands: L9W, GOL, EJR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-05-12
Ligands: L9W, GOL, EJR
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Oestrogen Receptor Ligand Binding Domain In Complex With Compound 16
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2021-01-20 Classification: GENE REGULATION Ligands: QNE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-20
Ligands: QNE
 |
Oestrogen Receptor Ligand Binding Domain In Complex With Compound 28
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.97 Å Release Date: 2021-01-20 Classification: GENE REGULATION Ligands: QNH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-20
Ligands: QNH
 |
Oestrogen Receptor Ligand Binding Domain In Complex With Compound 18
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2021-01-20 Classification: GENE REGULATION Ligands: QNK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-01-20
Ligands: QNK
 |
Human Erk2 With Erk1/2 Inhibitor, Azd0364.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.33 Å Release Date: 2019-11-20 Classification: TRANSFERASE Ligands: LHZ, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-11-20
Ligands: LHZ, SO4, EDO
 |
Era_L536S (L536S/C381S/C471S,C530S) In Complex With A Bridged Tetracyclic Indole (Compound 8)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.77 Å Release Date: 2019-10-30 Classification: GENE REGULATION Ligands: LRQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-10-30
Ligands: LRQ
 |
Era_L536S (L536S/C381S/C471S,C530S) In Complex With A Tricyclic Indole (Compound 6)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.74 Å Release Date: 2019-10-30 Classification: GENE REGULATION Ligands: LVH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-10-30
Ligands: LVH
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Tricyclic Indazoles A Novel Class Of Selective Estrogen Receptor Degrader Antagonists
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2019-01-23 Classification: DNA BINDING PROTEIN Ligands: H8W |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-01-23
Ligands: H8W
 |
Human Erk2 With An Erk1/2 Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.74 Å Release Date: 2017-04-19 Classification: TRANSFERASE Ligands: SO4, 8X2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-04-19
Ligands: SO4, 8X2
 |
Human Erk2 With An Erk1/2 Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.14 Å Release Date: 2017-04-19 Classification: TRANSFERASE Ligands: SO4, 8X5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-04-19
Ligands: SO4, 8X5