Search Count: 18
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Bace1 In Complex With 4-(Cyclohexylamino)-1-(3-Fluorophenyl)-8-(3-Isopropoxybenzyl)-1,3,8-Triazaspiro[4.5]Dec-3-En-2-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2015-08-05 Classification: Hydrolase/hydrolase inhibitor Ligands: 4QA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-05
Ligands: 4QA
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Bace1 In Complex With 8-(3-((1-Aminopropan-2-Yl)Oxy)Benzyl)-4-(Cyclohexylamino)-1-(3-Fluorophenyl)-1,3,8-Triazaspiro[4.5]Dec-3-En-2-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2015-08-05 Classification: Hydrolase/Hydrolase inhibitor Ligands: 4QD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-05
Ligands: 4QD
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Bace1 In Complex With 8-Benzyl-4-(Cyclohexylamino)-1-(3-Fluorophenyl)-7-Methyl-1,3,8-Triazaspiro[4.5]Dec-3-En-2-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2015-08-05 Classification: Hydrolase/hydrolase inhibitor Ligands: 4QF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-08-05
Ligands: 4QF
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Discovery Of Pyrrolidine-Based B-Secretase Inhibitors: Lead Advancement Through Conformational Design For Maintenance Of Ligand Binding Efficiency
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2012-01-18 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 508, SO4, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-01-18
Ligands: 508, SO4, GOL
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Discovery Of Aminoheterocycles As A Novel Beta-Secretase Inhibitor Class
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2009-07-07 Classification: HYDROLASE Ligands: B35 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-07-07
Ligands: B35
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Crystal Structure Of Bace1 Bound To Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2009-02-03 Classification: HYDROLASE Ligands: SO4, GOL, 5MS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-02-03
Ligands: SO4, GOL, 5MS
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Crystal Structure Of Human Beta Secretase Complexed With I21
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2008-04-29 Classification: HYDROLASE Ligands: I21 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-04-29
Ligands: I21
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Crystal Structure Of Human Beta Secretase Complexed With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2008-04-22 Classification: HYDROLASE Ligands: SO4, 35A |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-04-22
Ligands: SO4, 35A
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Crystal Structure Of Human Beta Secretase Complexed With Ixs
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2008-04-22 Classification: HYDROLASE Ligands: IXS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-04-22
Ligands: IXS
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Crystal Structure Of Human Bace-1 Bound To Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2007-11-13 Classification: HYDROLASE Ligands: L00 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-11-13
Ligands: L00
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Crystal Structure Of Human Beta Secretase Complexed With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2007-08-14 Classification: HYDROLASE Ligands: QIN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-08-14
Ligands: QIN
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Crystal Structure Of Human Beta Secretase Complexed With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2007-08-14 Classification: HYDROLASE Ligands: MY9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-08-14
Ligands: MY9
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Crystal Structure Of Human Beta Secretase Complexed With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2007-06-05 Classification: HYDROLASE Ligands: SO4, 712 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-06-05
Ligands: SO4, 712
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Crystal Structure Of Human Beta-Secretase Complexed With L-L000430,469
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2005-12-06 Classification: HYDROLASE Ligands: 3BN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2005-12-06
Ligands: 3BN
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Crystal Structure Of Human Beta Secretase Complexed With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2005-10-18 Classification: HYDROLASE Ligands: 5HA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2005-10-18
Ligands: 5HA
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Co-Crystal Structure Of Human Farnesyltransferase With Farnesyldiphosphate And Inhibitor Compound 33A
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2003-07-08 Classification: TRANSFERASE Ligands: ZN, FPP, BNE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2003-07-08
Ligands: ZN, FPP, BNE
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Co-Crystal Structure Of Human Farnesyltransferase With Farnesyldiphosphate And Inhibitor Compound 66
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2002-06-19 Classification: TRANSFERASE Ligands: ZN, FPP, U66 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2002-06-19
Ligands: ZN, FPP, U66
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Co-Crystal Structure Of Human Farnesyltransferase With Farnesyldiphosphate And Inhibitor Compound 49
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2002-06-19 Classification: TRANSFERASE Ligands: ACY, ZN, FPP, U49 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2002-06-19
Ligands: ACY, ZN, FPP, U49