Search Count: 36
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Crystal Structure Of P53 Y220C Mutant In Complex With Pc-9859
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2024-12-18 Classification: TRANSFERASE Ligands: A1ARZ, ZN, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-12-18
Ligands: A1ARZ, ZN, CL
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Crystal Structure Of Ap2 Associated Kinase 1 Complexed With 5-[(4-Aminopiperidin-1-Yl)Methyl]-N-{3-[5-(Propan-2-Yl)-1,3,4-Thiadiazol-2-Yl]Phenyl}Pyrrolo[2,1-F][1,2,4]Triazin-4-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2023-07-12 Classification: TRANSFERASE Ligands: YFV, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-07-12
Ligands: YFV, SO4
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Crystal Structure Of Ap2 Associated Kinase 1 Complexed With (5P)-3-({(8R)-5-[(4-Aminopiperidin-1-Yl)Methyl]Pyrrolo[2,1-F][1,2,4]Triazin-4-Yl}Amino)-5-[2-(Propan-2-Yl)-2H-Tetrazol-5-Yl]Phenol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2023-07-12 Classification: TRANSFERASE Ligands: ZRR, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-07-12
Ligands: ZRR, SO4
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G-925 Bound To The Smarca4 (Brg1) Bromodomain
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.16 Å Release Date: 2022-08-17 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: GGU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-08-17
Ligands: GGU
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G-059 Bound To The Smarca4 (Brg1) Bromodomain
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.61 Å Release Date: 2022-08-17 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: GJN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-08-17
Ligands: GJN
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Crystal Structure Of The First Bromodomain Of Human Brd4 With Benzodiazepine Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2021-09-01 Classification: GENE REGULATION/INHIBITOR Ligands: UDV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-09-01
Ligands: UDV
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Crystal Structure Of Hepatis C Virus Protease (Ns3) Complexed With Tripeptidic Acyl Sulfonamide Inhibitor (Compound 16)
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION Resolution:1.69 Å Release Date: 2018-03-21 Classification: HYDROLASE Ligands: Z1B, ZN, CL, ACT |
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION
Release Date: 2018-03-21
Ligands: Z1B, ZN, CL, ACT
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Crystal Structure Of Hepatis C Virus Protease (Ns3) Complexed With Tripeptidic Acyl Sulfonamide Inhibitor (Compound 18)
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION Resolution:1.97 Å Release Date: 2018-03-21 Classification: HYDROLASE Ligands: Z1E, ZN |
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION
Release Date: 2018-03-21
Ligands: Z1E, ZN
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Structure Of Human Polycomb Repressive Complex 2 (Prc2) With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.47 Å Release Date: 2017-02-22 Classification: Transferase/Inhibitor Ligands: ZN, 74D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: ZN, 74D
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Brd9 In Complex With Cpd1 (6-Methyl-1,6-Dihydro-7H-Pyrrolo[2,3-C]Pyridin-7-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.04 Å Release Date: 2016-10-12 Classification: RNA BINDING PROTEIN Ligands: EDO, PEG, 67N |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-10-12
Ligands: EDO, PEG, 67N
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Brd9 In Complex With Cpd2 (N,N-Dimethyl-3-(6-Methyl-7-Oxo-6,7-Dihydro-1H-Pyrrolo[2,3-C]Pyridin-4-Yl)Benzamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.18 Å Release Date: 2016-10-12 Classification: RNA BINDING PROTEIN Ligands: 67B |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-10-12
Ligands: 67B
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Brd9 In Complex With Cpd4 ((E)-3-(6-(But-2-En-1-Yl)-7-Oxo-6,7-Dihydro-1H-Pyrrolo[2,3-C]Pyridin-4-Yl)-N,N-Dimethylbenzamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.45 Å Release Date: 2016-10-12 Classification: TRANSCRIPTION Ligands: 69G |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-10-12
Ligands: 69G
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Brd4 In Complex With Cpd2 (N,N-Dimethyl-3-(6-Methyl-7-Oxo-6,7-Dihydro-1H-Pyrrolo[2,3-C]Pyridin-4-Yl)Benzamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.45 Å Release Date: 2016-10-12 Classification: TRANSCRIPTION Ligands: 67B, EDO, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-10-12
Ligands: 67B, EDO, DMS
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Brd4 In Complex With Cpd4 ((E)-3-(6-(But-2-En-1-Yl)-7-Oxo-6,7-Dihydro-1H-Pyrrolo[2,3-C]Pyridin-4-Yl)-N,N-Dimethylbenzamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2016-10-12 Classification: TRANSCRIPTION Ligands: PGE, EDO, DMS, 69G, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-10-12
Ligands: PGE, EDO, DMS, 69G, GOL
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Second Bromodomain Of Taf1 Bound To A Pyrrolopyridone Compound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2016-06-08 Classification: PROTEIN BINDING/INHIBITOR Ligands: 67C |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-08
Ligands: 67C
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Taf1(2) Bound To A Pyrrolopyridone Compound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.21 Å Release Date: 2016-06-08 Classification: PROTEIN BINDING/INHIBITOR Ligands: 67B, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-08
Ligands: 67B, CA
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Crystal Structure Of Hepatis C Virus Protease (Ns3) Complexed With Bms-605339 Aka N-(Tert-Butoxycarbonyl)-3-Me Thyl-L-Valyl-(4R)-N-((1R,2S)-1-((Cyclopropylsulfonyl)Carba Moyl)-2-Vinylcyclopropyl)-4-((6-Methoxy-1-Isoquinolinyl)Ox Y)-L-Prolinamide
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION Resolution:1.62 Å Release Date: 2014-03-26 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 2R8, ZN, SO4, GOL |
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION
Release Date: 2014-03-26
Ligands: 2R8, ZN, SO4, GOL
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Crystal Structure Of Hepatis C Virus Protease (Ns3) Complexed With Bms-650032 Aka N-(Tert-Butoxycarbonyl)-3-Me Thyl-L-Valyl-(4R)-4-((7-Chloro-4-Methoxy-1-Isoquinolinyl)O Xy)-N-((1R,2S)-1-((Cyclopropylsulfonyl)Carbamoyl)-2-Vinylc Yclopropyl)-L-Prolinamide
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2014-03-26 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 2R9, ZN |
Organism: Hepatitis c virus
Method: X-RAY DIFFRACTION
Release Date: 2014-03-26
Ligands: 2R9, ZN
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Crystal Structure Of Beta-Site App-Cleaving Enzyme 1 (Bace-Wt) Complex With N-(N-(4-Amino-3,5- Dichlorobenzyl)Carbamimidoyl)-3-(4-Methoxyphenyl)-5- Methyl-4-Isothiazolecarboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2012-10-10 Classification: HYDROLASE/INHIBITOR Ligands: 0VA, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-10-10
Ligands: 0VA, IOD
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Crystal Structure Of Beta-Site App-Cleaving Enzyme 1 (Bace-Db-Mut) Complex With N-(N-(4- Acetamido-3-Chloro-5-Methylbenzyl)Carbamimidoyl)-3-(4- Methoxyphenyl)-5-Methyl-4-Isothiazolecarboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2012-10-10 Classification: HYDROLASE/INHIBITOR Ligands: 0VB, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-10-10
Ligands: 0VB, IOD