Search Count: 23
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Bruton'S Tyrosine Kinase In Complex With A T-Butyl Cyanoacrylamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2015-05-13 Classification: TRANSFERASE Ligands: 4C9, NA, EDO, SO4, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-05-13
Ligands: 4C9, NA, EDO, SO4, CL
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Crystal Structure Of Btk Kinase Domain Complexed With 6-(Dimethylamino)-2-[2-(Hydroxymethyl)-3-[1-Methyl-5-[[5-(Morpholine-4-Carbonyl)-2-Pyridyl]Amino]-6-Oxo-3-Pyridyl]Phenyl]-3,4-Dihydroisoquinolin-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2014-12-24 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3OU, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-24
Ligands: 3OU, DMS
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Crystal Structure Of Btk Kinase Domain Complexed With 6-(Dimethylamino)-8-Fluoro-2-[2-(Hydroxymethyl)-3-[1-Methyl-5-[[5-(Morpholine-4-Carbonyl)-2-Pyridyl]Amino]-6-Oxo-3-Pyridyl]Phenyl]Isoquinolin-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.17 Å Release Date: 2014-12-24 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3OV, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-24
Ligands: 3OV, DMS
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Crystal Structure Of Btk Kinase Domain Complexed With 2-[8-Fluoro-2-[2-(Hydroxymethyl)-3-[1-Methyl-5-[[5-(4-Methylpiperazin-1-Yl)-2-Pyridyl]Amino]-6-Oxo-3-Pyridyl]Phenyl]-1-Oxo-3,4-Dihydroisoquinolin-6-Yl]-2-Methyl-Propanenitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2014-12-24 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3P0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-24
Ligands: 3P0
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Crystal Structure Of Btk Kinase Domain Complexed With 4-Tert-Butyl-N-(3-{8-[4-(4-Methyl-Piperazine-1-Carbonyl)-Phenylamino]-Imidazo[1,2-A]Pyrazin-6-Yl}-Phenyl)-Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2014-05-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 481, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: 481, DMS
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Crystal Structure Of Btk Kinase Domain Complexed With 4-Methanesulfonyl-N-(3-{8-[4-(Morpholine-4-Carbonyl)-Phenylamino]-Imidazo[1,2-A]Pyrazin-6-Yl}-Phenyl)-Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2014-05-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2V1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: 2V1
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Crystal Structure Of Btk Kinase Domain Complexed With 1-[5-[3-(7-Tert-Butyl-4-Oxo-Quinazolin-3-Yl)-2-Methyl-Phenyl]-1-Methyl-2-Oxo-3-Pyridyl]-3-Methyl-Urea
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2014-05-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2V2, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: 2V2, DMS
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Crystal Structure Of Btk Kinase Domain Complexed With 6-Cyclopropyl-2-[3-[5-[[5-(4-Ethylpiperazin-1-Yl)-2-Pyridyl]Amino]-1-Methyl-6-Oxo-3-Pyridyl]-2-(Hydroxymethyl)Phenyl]-8-Fluoro-Isoquinolin-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2014-05-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2V3, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: 2V3, DMS
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Crystal Structure Of Jnk1 In Complex With Jip1 Peptide And 4-(4-Indazol-1-Yl-Pyrimidin-2-Ylamino)-Cyclohexan
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.42 Å Release Date: 2013-10-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1BJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-10-30
Ligands: 1BJ
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Crystal Structure Of Jnk1 In Complex With Jip1 Peptide And 4-{4-[4-(3-Methanesulfonyl-Propoxy)-Indazol-1-Yl]-Pyrimidin-2-Ylamino}-Cyclohexan
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2013-10-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1BK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-10-30
Ligands: 1BK
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Crystal Structure Of Spleen Tyrosine Kinase Complexed With 2-(3,4,5-Trimethoxy-Phenyl)-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxylic Acid Isopropylamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2013-10-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1B4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-10-30
Ligands: 1B4
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Crystal Structure Of Spleen Tyrosine Kinase Complexed With 2-(6-Chloro-1-Methyl-1H-Indazol-3-Yl)-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxylic Acid Isopropylamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2013-10-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1B5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-10-30
Ligands: 1B5
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Crystal Structure Of Spleen Tyrosine Kinase Complexed With 2-(5,6,7,8-Tetrahydro-Imidazo[1,5-A]Pyridin-1-Yl)-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxylic Acid Tert-Butylamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2013-10-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1B6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-10-30
Ligands: 1B6
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Crystal Structure Of Spleen Tyrosine Kinase Complexed With 6-((1R,2S)-2-Amino-Cyclohexylamino)-4-(6-Ethyl-Pyridin-2-Ylamino)-Pyridazine-3-Carboxylic Acid Amide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2013-07-10 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0VH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-07-10
Ligands: 0VH
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Potent And Selective Inhibitors Of Pi3K-Delta: Obtaining Isoform Selectivity From The Affinity Pocket And Tryptophan Shelf
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.67 Å Release Date: 2013-04-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0SC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-17
Ligands: 0SC
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Potent And Selective Inhibitors Of Pi3K-Delta: Obtaining Isoform Selectivity From The Affinity Pocket And Tryptophan Shelf
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2013-04-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0SD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-17
Ligands: 0SD
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Potent And Selective Inhibitors Of Pi3K-Delta: Obtaining Isoform Selectivity From The Affinity Pocket And Tryptophan Shelf
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.94 Å Release Date: 2013-04-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0SE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-17
Ligands: 0SE
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Crystal Structure Of Spleen Tyrosine Kinase Complexed With 3-(8-{4-[Ethyl-(2-Hydroxy-Ethyl)-Amino]-Phenylamino}-Imidazo[1,2-A]Pyrazin-5-Yl)-Phenol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.32 Å Release Date: 2013-01-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0VE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-01-30
Ligands: 0VE
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Crystal Structure Of Spleen Tyrosine Kinase Complexed With N-{(S)-1-[7-(3,4-Dimethoxy-Phenylamino)-Thiazolo[5,4-D]Pyrimidin-5-Yl]-Pyrrolidin-3-Yl}-Terephthalamic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2013-01-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0VF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-01-30
Ligands: 0VF
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Crystal Structure Of Spleen Tyrosine Kinase Complexed With [6-((S)-2-Methyl-Pyrrolidin-1-Yl)-Pyridin-2-Yl]-(6-Phenyl-Imidazo[1,2-B]Pyridazin-8-Yl)-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2013-01-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0VG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-01-30
Ligands: 0VG