Search Count: 10
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Factor Xia In Complex With The Inhibitor Methyl ((10R,14S)- 14-(4-(3-Chloro-2,6-Difluorophenyl)-6-Oxo-3,6-Dihydro- 1(2H)-Pyridinyl)-10-Methyl-9-Oxo-8,16- Diazatricyclo[13.3.1.0~2,7~]Nonadeca-1(19),2,4,6,15,17- Hexaen-5-Yl)Carbamate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2020-06-10 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: SWP, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-06-10
Ligands: SWP, SO4, EDO
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Factor Xia In Complex With The Inhibitor Methyl [(2R,7S)-7-({(2E)-3-[5-Chloro-2-(1H-Tetrazol-1-Yl)Phenyl]Prop-2-Enoyl}Amino)-2-(Trifluoromethyl)-2,3,4,5,6,7-Hexahydro-1H-8,11-Epimino-1,9-Benzodiazacyclotridecin-14-Yl]Carbamate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2020-01-29 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: QLS, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-29
Ligands: QLS, SO4, EDO
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Factor Xia In Complex With The Inhibitor Methyl (2R,7S)-7-({(2E)-3-[5-Chloro-2-(1H-Tetrazol-1-Yl)Phenyl]Prop-2-Enoyl}Amino)-14-[(Methoxycarbonyl)Amino]-2,3,4,5,6,7-Hexahydro-1H-8,11-Epimino-1,9-Benzodiazacyclotridecine-2-Carboxylate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.12 Å Release Date: 2020-01-29 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: QLM, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-29
Ligands: QLM, SO4, EDO
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Factor Xia In Complex With The Inhibitor Ethyl (2R,7S)-7-({(2E)-3-[5-Chloro-2-(1H-Tetrazol-1-Yl)Phenyl]Prop-2-Enoyl}Amino)-14-[(Methoxycarbonyl)Amino]-1,2,3,4,5,6,7,9-Octahydro-11,8-(Azeno)-1,9-Benzodiazacyclotridecine-2-Carboxylate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2020-01-29 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: QLD, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-29
Ligands: QLD, SO4, EDO
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Factor Xia In Complex With The Inhibitor Ethyl (2R,7S)-7-({(2E)-3-[5-Chloro-2-(1H-Tetrazol-1-Yl)Phenyl]Prop-2-Enoyl}Amino)-15-[(Methoxycarbonyl)Amino]-2,3,4,5,6,7-Hexahydro-1H-12,8-(Metheno)-1,9-Benzodiazacyclotetradecine-2-Carboxylate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.89 Å Release Date: 2020-01-29 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: QLJ, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-29
Ligands: QLJ, SO4, EDO
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Factor Xia In Complex With The Inhibitor 4-[(N-{(2E)-3-[5-Chloro-2-(1H-Tetrazol-1-Yl)Phenyl]Prop-2-Enoyl}-L-Phenylalanyl)Amino]Benzoic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.08 Å Release Date: 2015-12-09 Classification: Hydrolase/Hydrolase Inhibitor Ligands: 5JM, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-12-09
Ligands: 5JM, SO4, EDO
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Factor Xia In Complex With The Inhibitor N-[(1S)-1-Benzyl-2-[2-[5-Chloro-2-(Tetrazol-1-Yl)Phenyl]Ethylamino]-2-Oxo-Ethyl]-4-Hydroxy-2-Oxo-1H-Quinoline-6-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2015-12-09 Classification: Hydrolase/Hydrolase Inhibitor Ligands: 7P0, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-12-09
Ligands: 7P0, SO4, EDO
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Factor Xia In Complex With The Inhibitor Methyl (4-{4-Chloro-2-[(1S)-1-({(2E)-3-[5-Chloro-2-(1H-Tetrazol-1-Yl)Phenyl]Prop-2-Enoyl}Amino)-2-Phenylethyl]-1H-Imidazol-5-Yl}Phenyl)Carbamate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2015-05-27 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 4GR, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-05-27
Ligands: 4GR, SO4, EDO
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Factor Xia In Complex With The Inhibitor Methyl (4-{4-Chloro-2-[(1S)-1-({(2E)-3-[5-Chloro-2-(1H-Tetrazol-1-Yl)Phenyl]Prop-2-Enoyl}Amino)-3-(Morpholin-4-Yl)-3-Oxopropyl]-1H-Imidazol-5-Yl}Phenyl)Carbamate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2015-05-27 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 4D5, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-05-27
Ligands: 4D5, SO4, EDO
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Factor Xia In Complex With The Inhibitor (2E)-N-[(1S)-1-[5-Chloro-4-(4-Hydroxy-2-Oxo-1,2-Dihydroquinolin-6-Yl)-1H-Imidazol-2-Yl]-3-(4-Methylpiperazin-1-Yl)-3-Oxopropyl]-3-[5-Chloro-2-(1H-Tetrazol-1-Yl)Phenyl]Prop-2-Enamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2015-05-27 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 4CE, SO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-05-27
Ligands: 4CE, SO4, EDO