Search Count: 12
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Crystal Structure Of Pyrrolidine Amide Inhibitor [(3S)-3-(4-Bromo-1H-Pyrazol-1-Yl)Pyrrolidin-1-Yl][3-(Propan-2-Yl)-1H-Pyrazol-5-Yl]Methanone (Compound 35) In Complex With Kdm5A
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2017-05-10 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NI, ZN, 90S, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: NI, ZN, 90S, SO4
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Crystal Structure Of Selective Pyrrolidine Amide Kdm5A Inhibitor N-{(3R)-1-[3-(Propan-2-Yl)-1H-Pyrazole-5-Carbonyl]Pyrrolidin-3-Yl}Cyclopropanecarboxamide (Compound 48)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.05 Å Release Date: 2017-05-10 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NI, ZN, 90V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: NI, ZN, 90V
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Structure Of Human Polycomb Repressive Complex 2 (Prc2) With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.47 Å Release Date: 2017-02-22 Classification: Transferase/Inhibitor Ligands: ZN, 74D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: ZN, 74D
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Kdm4C Bound To Pyrazolo-Pyrimidine Scaffold
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2016-08-17 Classification: OXIDOREDUCTASE Ligands: FE2, ZN, 6X9, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-08-17
Ligands: FE2, ZN, 6X9, CL
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Structure Of Histone Lysine Demethylase Kdm5A In Complex With Selective Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.14 Å Release Date: 2016-05-18 Classification: Oxidoreductase/Inhibitor Ligands: NI, ZN, 50P |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-05-18
Ligands: NI, ZN, 50P
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Crystal Structure Of The First Bromodomain Of Human Brd4 Bound To Cpi-0610
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2016-02-10 Classification: TRANSCRIPTION Ligands: 62G |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-10
Ligands: 62G
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Crystal Structure Of The First Bromodomain Of Human Brd4 Bound To Benzoisoxazoloazepine 3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2016-02-10 Classification: TRANSCRIPTION Ligands: 62V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-10
Ligands: 62V
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Discovery Of Benzotriazolo Diazepines As Orally-Active Inhibitors Of Bet Bromodomains: Crystal Structure Of Brd4 With Cpi-13
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.20 Å Release Date: 2015-11-11 Classification: SIGNALING PROTEIN Ligands: FMT, 3X0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-11-11
Ligands: FMT, 3X0
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Crystal Structure Of The First Bromodomain Of Human Brd4 Bound To Benzotriazolo-Diazepine Scaffold
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2015-04-08 Classification: TRANSCRIPTION Ligands: 558 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-04-08
Ligands: 558
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Crystal Structure Of The First Bromodomain Of Human Brd4 With Benzotriazolo-Diazepine Scaffold
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.06 Å Release Date: 2015-04-08 Classification: SIGNALING PROTEIN Ligands: 559 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-04-08
Ligands: 559
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Structure Of Brd4 Bromodomain 1 With A 3-Methyl-4-Phenylisoxazol-5-Amine Fragment
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.29 Å Release Date: 2013-08-07 Classification: TRANSCRIPTION REGULATOR/INHIBITOR Ligands: FMT, 1XA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-07
Ligands: FMT, 1XA
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Structure Of Brd4 Bromodomain 1 With A Dimethyl Thiophene Isoxazole Azepine Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.21 Å Release Date: 2013-08-07 Classification: TRANSCRIPTION REGULATOR/INHIBITOR Ligands: 1XB |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-07
Ligands: 1XB