Search Count: 21
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Structural Studies On Bio-Active Compounds. Crystal Structure And Molecular Modeling Studies On The Pneumocystis Carinii Dihydrofolate Reductase Cofactor Complex With Tab, A Highly Selective Antifolate.
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2004-01-20 Classification: OXIDOREDUCTASE Ligands: NDP, TAB |
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION
Release Date: 2004-01-20
Ligands: NDP, TAB
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Analysis Of Two Polymorphic Forms Of A Pyrido[2,3-D]Pyrimidine N9-C10 Reverse-Bridge Antifolate Binary Complex With Human Dihydrofolate Reductase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2003-04-01 Classification: OXIDOREDUCTASE Ligands: SO4, DTM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2003-04-01
Ligands: SO4, DTM
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Analysis Of Two Polymorphic Forms Of A Pyrido[2,3-D]Pyrimidine N9-C10 Reverse-Bridge Antifolate Binary Complex With Human Dihydrofolate Reductase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2003-04-01 Classification: OXIDOREDUCTASE Ligands: SO4, DTM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2003-04-01
Ligands: SO4, DTM
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Crystal Structure Of Pneumocystis Carinii Dihydrofolate Reductase Ternary Complex With Pt653 And Nadph
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2002-12-12 Classification: OXIDOREDUCTASE Ligands: PMD, NDP |
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION
Release Date: 2002-12-12
Ligands: PMD, NDP
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Analysis Of Quinazoline And Pyridopyrimidine N9-C10 Reversed Bridge Antifolates In Complex With Nadp+ And Pneumocystis Carinii Dihydrofolate Reductase
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2002-08-28 Classification: OXIDOREDUCTASE Ligands: NAP, COG |
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION
Release Date: 2002-08-28
Ligands: NAP, COG
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Analysis Of Quinazoline And Pyrido[2,3D]Pyrimidine N9-C10 Reversed Bridge Antifolates In Complex With Nadp+ And Pneumocystis Carinii Dihydrofolate Reductase
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2002-08-28 Classification: OXIDOREDUCTASE Ligands: NAP, COQ |
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION
Release Date: 2002-08-28
Ligands: NAP, COQ
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Crystal Structure Of The Insecticidal Bacterial Del Endotoxin Cry3Bb1 Bacillus Thuringiensis
Organism: Bacillus thuringiensis
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2001-09-19 Classification: TOXIN |
Organism: Bacillus thuringiensis
Method: X-RAY DIFFRACTION
Release Date: 2001-09-19
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Design, Synthesis And X-Ray Crystal Structure Of A Potent Dual Inhibitor Of Thymidylate Synthase And Dihydrofolate Reductase As An Antitumor Agent.
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2001-05-17 Classification: OXIDOREDUCTASE Ligands: NAP, GPB |
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION
Release Date: 2001-05-17
Ligands: NAP, GPB
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Ligand Induced Conformational Changes In The Crystal Structures Of Pneumocystis Carinii Dihydrofolate Reductase Complexes With Folate And Nadp+
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2000-03-29 Classification: OXIDOREDUCTASE Ligands: NAP, FOL |
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION
Release Date: 2000-03-29
Ligands: NAP, FOL
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Ligand Induced Conformational Changes In The Crystal Structures Of Pneumocystis Carinii Dihydrofolate Reductase Complexes With Folate And Nadp+
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2000-03-29 Classification: OXIDOREDUCTASE Ligands: NAP, MTX |
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION
Release Date: 2000-03-29
Ligands: NAP, MTX
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Ligand Induced Conformational Changes In The Crystal Structures Of Pneumocystis Carinii Dihydrofolate Reductase Complexes With Folate And Nadp+
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2000-03-29 Classification: OXIDOREDUCTASE Ligands: FOL |
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION
Release Date: 2000-03-29
Ligands: FOL
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Ligand Induced Conformational Changes In The Crystal Structures Of Pneumocystis Carinii Dihydrofolate Reductase Complexes With Folate And Nadp+
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2000-03-06 Classification: OXIDOREDUCTASE Ligands: NAP, FOL |
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION
Release Date: 2000-03-06
Ligands: NAP, FOL
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Structure-Based Design And Synthesis Of Lipophilic 2,4-Diamino-6-Substituted Quinazolines And Their Evaluation As Inhibitors Of Dihydrofolate Reductase And Potential Antitumor Agents
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 1998-08-12 Classification: OXIDOREDUCTASE Ligands: NDP, PRD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 1998-08-12
Ligands: NDP, PRD
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Human Dihydrofolate Reductase, Orthorhombic (P21 21 21) Crystal Form
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 1998-05-27 Classification: OXIDOREDUCTASE Ligands: NDP, COP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 1998-05-27
Ligands: NDP, COP
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Human Dihydrofolate Reductase, Monoclinic (P21) Crystal Form
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 1998-04-29 Classification: OXIDOREDUCTASE Ligands: NDP, COP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 1998-04-29
Ligands: NDP, COP
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Comparison Of Ternary Crystal Complexes Of Human Dihydrofolate Reductase With Nadph And A Classical Antitumor Furopyrimdine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 1998-01-28 Classification: OXIDOREDUCTASE Ligands: NDP, MOT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 1998-01-28
Ligands: NDP, MOT
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Comparison Of Ternary Crystal Complexes Of Human Dihydrofolate Reductase With Nadph And A Classical Antitumor Furopyrimdine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 1998-01-28 Classification: OXIDOREDUCTASE Ligands: NDP, MOT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 1998-01-28
Ligands: NDP, MOT
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Comparison Of Ternary Crystal Complexes Of Human Dihydrofolate Reductase With Nadph And A Classical Antitumor Furopyrimdine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 1998-01-28 Classification: OXIDOREDUCTASE Ligands: NDP, MOT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 1998-01-28
Ligands: NDP, MOT
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Comparison Of Ternary Complexes Of Pneumocystis Carinii And Wild Type Human Dihydrofolate Reductase With Coenzyme Nadph And A Novel Classical Antitumor Furo[2,3D]Pyrimidine Antifolate
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 1997-12-24 Classification: OXIDOREDUCTASE Ligands: NDP, MOT |
Organism: Pneumocystis carinii
Method: X-RAY DIFFRACTION
Release Date: 1997-12-24
Ligands: NDP, MOT
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Methotrexate-Resistant Variants Of Human Dihydrofolate Reductase With Substitution Of Leucine 22: Kinetics, Crystallography And Potential As Selectable Markers
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 1995-04-20 Classification: OXIDOREDUCTASE Ligands: NDP, MXA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 1995-04-20
Ligands: NDP, MXA