Search Count: 12
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Crystal Structure Of Irak4-Hsa Complexed With N-[(2R)-2-Fluoro-3-Hydroxy-3-Methylbutyl]-6-[(5-Fluoropyri-Yl)Amino]-4-[(Propan-2-Yl)Amino]Pyridine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.89 Å Release Date: 2025-02-12 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ZVD, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: ZVD, SO4
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Crystal Structure Of Irak4-Hsa Complexed With Bms-986126; 6-((5-Cyano-2-Pyrimidinyl)Amino)-N-((2R)-2-Fluoro-3-Hydroxhylbutyl)-4-(Isopropylamino)Nicotinamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.69 Å Release Date: 2025-02-12 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ZVG, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: ZVG, SO4
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Crystal Structure Of Irak4-Hsa Complexed With Bms-986147; 6-{5-Cyano-1H-Pyrazolo[3,4-B]Pyridin-1-Yl}-N-[(2R)-2-Fluorroxy-3-Methylbutyl]-4-[(Propan-2-Yl)Amino]Pyridine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.76 Å Release Date: 2025-02-12 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, ZVA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: SO4, ZVA
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Factor Xia (Pichia Pastoris; C500S [C122S]) In Complex With The Inhibitor Milvexian (Bms-986177), Iupac Name:(6R,10S)-10-{4-[5-Chloro-2-(4-Chloro-1H-1,2,3-Triazol-1-Yl)Phenyl]-6- Oxopyrimidin-1(6H)-Yl}-1-(Difluoromethyl)-6-Methyl-1,4,7,8,9,10-Hexahydro-15,11- (Metheno)Pyrazolo[4,3-B][1,7]Diazacyclotetradecin-5(6H)-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:0.92 Å Release Date: 2021-09-15 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NAG, YXG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-09-15
Ligands: NAG, YXG
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Crystal Structure Of Rar-Related Orphan Receptor C In Complex With A Novel Inverse Agonist
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2020-08-12 Classification: TRANSCRIPTION/Agonist Ligands: V27 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-12
Ligands: V27
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Structure Of Human Pregnane X Receptor Ligand Binding Domain Bound Tethered With Src Co-Activator Peptide And Compound-3 Aka 1,1,1,3,3,3-Hexafluoro-2-{4-[1-(4- Luorobenzenesulfonyl)Cyclopentyl]Phenyl}Propan-2-Ol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2020-02-12 Classification: TRANSFERASE Ligands: L7D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-02-12
Ligands: L7D
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Crystal Structure Of Jak3 Kinase Domain In Complex With A Pyrrolopyridazine Carboxamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.33 Å Release Date: 2019-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: Z3A |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-22
Ligands: Z3A
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Btk In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.42 Å Release Date: 2019-04-03 Classification: TRANSFERASE/INHIBITOR Ligands: LTJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-04-03
Ligands: LTJ
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Crystal Structure Of Rar-Related Orphan Receptor C In Complex With A Phenyl (3-Phenylpyrrolidin-3-Yl)Sulfone Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.29 Å Release Date: 2019-03-20 Classification: TRANSCRIPTION/INHIBITOR Ligands: L8A |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-03-20
Ligands: L8A
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Identification Of Bicyclic Hexafluoroisopropyl Alcohol Sulfonamides As Rorgt/Rorc Inverse Agonists
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2017-12-20 Classification: TRANSCRIPTION/TRANSCRIPTION INHIBITOR Ligands: XGH, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-12-20
Ligands: XGH, SO4
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Structure Of Human Pregnane X Receptor Ligand Binding Domain Bound Tethered With Src Co-Activator Peptide And Compound 25A Aka Bicyclic Hexafluoroisopropyl 2 Alcohol Sulfonamides
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.56 Å Release Date: 2017-12-20 Classification: NUCLEAR PROTEIN Ligands: XGH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-12-20
Ligands: XGH
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Crystal Structure Of Bruton Agammabulinemia Tyrosine Kinase Complexed With Bms-986142 Aka (2S)-6-Fluoro-5-[3-(8-Fluoro-1-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydroquinazolin-3-Yl)-2-Methylphenyl]-2-(2-Hydroxypropan-2-Yl)-2,3,4,9-Tetrahydro-1H-Carbazole-8-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2017-03-08 Classification: TRANSFERASE Ligands: 73T |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-08
Ligands: 73T