Search Count: 40
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Displacement Of Wdr5 From Chromatin By A Pharmacological Win Site Inhibitor With Picomolar Affinity
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2019-03-13 Classification: gene regulation/inhibitor Ligands: HLS, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-03-13
Ligands: HLS, SO4
 |
Displacement Of Wdr5 From Chromatin By A Pharmacological Win Site Inhibitor With Picomolar Affinity
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.10 Å Release Date: 2019-03-13 Classification: gene regulation/inhibitor Ligands: HLP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-03-13
Ligands: HLP
 |
Displacement Of Wdr5 From Chromatin By A Pharmacological Win Site Inhibitor With Picomolar Affinity
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.66 Å Release Date: 2019-03-13 Classification: gene regulation/inhibitor Ligands: HLJ, EPE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-03-13
Ligands: HLJ, EPE
 |
Discovery Of Potent 2-Aryl-6,7-Dihydro-5Hpyrrolo[ 1,2-A]Imidazoles As Wdr5 Win-Site Inhibitors Using Fragment-Based Methods And Structure-Based Design
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.22 Å Release Date: 2019-03-13 Classification: gene regulation/inhibitor Ligands: HLM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-03-13
Ligands: HLM
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Wdr5 Covalently Modified At Y228 By (R)-2-Sf
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2023-05-31 Classification: GENE REGULATION/INHIBITOR Ligands: XKN, GOL, SO4, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-05-31
Ligands: XKN, GOL, SO4, CL
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Wd Repeat-Containing Protein 5 Complexed With N-[(3,5-Dimethoxyphenyl)Methyl]-4'-Fluoro-5-{[(2E)-2-Imino-3-Methyl-2,3-Dihydro-1H-Imidazol-1-Yl]Methyl}-2'-Methyl[1,1'-Biphenyl]-3-Carboxamide (Compound 13)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.02 Å Release Date: 2020-01-01 Classification: GENE REGULATION/INHIBITOR Ligands: Q6S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-01
Ligands: Q6S
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Crystal Structure Of Bptf Bromodomain In Complex With Inhibitor Pdy-3-077
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.66 Å Release Date: 2022-08-10 Classification: GENE REGULATION/INHIBITOR Ligands: P2L, DMS, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-08-10
Ligands: P2L, DMS, EDO
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Crystal Structure Of Bptf Bromodomain In Complex With Inhibitor Hz-01-105
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.45 Å Release Date: 2022-08-10 Classification: GENE REGULATION/INHIBITOR Ligands: DMS, YBV, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-08-10
Ligands: DMS, YBV, EDO
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Crystal Structure Of Bptf Bromodomain In Complex With Inhibitor Hz-03-112
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.39 Å Release Date: 2022-08-10 Classification: GENE REGULATION/INHIBITOR Ligands: Y9P, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-08-10
Ligands: Y9P, EDO
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Crystal Structure Of Bptf Bromodomain In Complex With Inhibitor Pdy-3-093
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.44 Å Release Date: 2022-08-10 Classification: GENE REGULATION/INHIBITOR Ligands: YC4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-08-10
Ligands: YC4, EDO
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Crystal Structure Of The First Bromodomain Of Human Brd4 With Benzodiazepine Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2021-09-01 Classification: GENE REGULATION/INHIBITOR Ligands: UDV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-09-01
Ligands: UDV
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Cocrystal Of Brd4(D1) With A Selective Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.53 Å Release Date: 2020-10-07 Classification: GENE REGULATION/INHIBITOR Ligands: EDO, U0D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-10-07
Ligands: EDO, U0D
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Crystal Structure Of Ttd-Phd Domain Of Uhrf1 In Complex With Mstella Peptide (Residues 85-119)
Organism: Homo sapiens, Mus musculus
Method: X-RAY DIFFRACTION Resolution:3.20 Å Release Date: 2024-11-06 Classification: GENE REGULATION/INHIBITOR Ligands: ZN |
Organism: Homo sapiens, Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2024-11-06
Ligands: ZN
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Cocrystal Of Brd4(D1) With A Methyl Carbamate Thiazepane Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.51 Å Release Date: 2020-01-01 Classification: GENE REGULATION/INHIBITOR Ligands: QJA, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-01
Ligands: QJA, EDO
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Cocrystal Of Brd4(D1) With A Ethyl Carbamate Thiazepane Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.31 Å Release Date: 2020-01-01 Classification: GENE REGULATION/INHIBITOR Ligands: EDO, QKD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-01
Ligands: EDO, QKD
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Cocrystal Of Brd4(D1) With A Methyl Carbamate Thiazepane Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.38 Å Release Date: 2020-01-01 Classification: GENE REGULATION/INHIBITOR Ligands: EDO, DMS, QJ1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-01
Ligands: EDO, DMS, QJ1
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Crystal Structure Of The First Bromodomain (Bd1) Of Human Brd3 Bound To Erk5-In-1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2021-07-14 Classification: GENE REGULATION/INHIBITOR Ligands: VYJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-07-14
Ligands: VYJ
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Crystal Structure Of The Second Bromodomain (Bd2) Of Human Brd3 Bound To Erk5-In-1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2021-07-14 Classification: GENE REGULATION/INHIBITOR Ligands: VYJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-07-14
Ligands: VYJ
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Crystal Structure Of The First Bromodomain (Bd1) Of Human Brd3 Bound To Sg3-179
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.45 Å Release Date: 2021-07-14 Classification: GENE REGULATION/INHIBITOR Ligands: 5W2, EDO, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-07-14
Ligands: 5W2, EDO, DMS
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Crystal Structure Of The First Bromodomain (Bd1) Of Human Brd2 Bound To Volasertib
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.83 Å Release Date: 2021-07-14 Classification: GENE REGULATION/INHIBITOR Ligands: IBI |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-07-14
Ligands: IBI