Search Count: 71
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Crystal Structure Of Wt Hiv-1 Reverse Transcriptase In Complex With 5-{2-[2-(2-Oxo-4-Sulfanylidene-3,4-Dihydropyrimidin-1(2H)-Yl)Ethoxy] Phenoxy}Naphthalene-2-Carbonitrile (Jlj648), A Non-Nucleoside Inhibitor
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION Resolution:2.37 Å Release Date: 2025-09-10 Classification: VIRAL PROTEIN Ligands: CL, SO4, A1BTU |
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION
Release Date: 2025-09-10
Ligands: CL, SO4, A1BTU
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Cryo-Em Structure Of Hiv-1 Reverse Transcriptase P66 Homodimer
Organism: Human immunodeficiency virus 1
Method: ELECTRON MICROSCOPY Resolution:3.85 Å Release Date: 2025-09-10 Classification: VIRAL PROTEIN |
Organism: Human immunodeficiency virus 1
Method: ELECTRON MICROSCOPY
Release Date: 2025-09-10
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Cryo-Em Structure Of Hiv-1 Reverse Transcriptase P66 Homodimer In Complex With 5-{2-[2-(2-Oxo-4-Sulfanylidene-3,4-Dihydropyrimidin-1(2H)-Yl)Ethoxy] Phenoxy}Naphthalene-2-Carbonitrile (Jlj648), A Non-Nucleoside Inhibitor
Organism: Human immunodeficiency virus 1
Method: ELECTRON MICROSCOPY Resolution:3.05 Å Release Date: 2025-09-10 Classification: VIRAL PROTEIN Ligands: A1BTU |
Organism: Human immunodeficiency virus 1
Method: ELECTRON MICROSCOPY
Release Date: 2025-09-10
Ligands: A1BTU
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Cryo-Em Structure Of Hiv-1 Reverse Transcriptase P66 Homodimer In Complex With 5-{2-[2-(2-Oxo-4-Sulfanylidene-3,4-Dihydropyrimidin-1(2H)-Yl)Ethoxy] Phenoxy}Naphthalene-2-Carbonitrile, A Non-Nucleoside Inhibitor, With An Additional Pocket Of Density
Organism: Human immunodeficiency virus 1
Method: ELECTRON MICROSCOPY Resolution:3.09 Å Release Date: 2025-09-10 Classification: VIRAL PROTEIN Ligands: A1BTU |
Organism: Human immunodeficiency virus 1
Method: ELECTRON MICROSCOPY
Release Date: 2025-09-10
Ligands: A1BTU
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Cryo-Em Structure Of Hiv-1 Reverse Transcriptase P66 Tetramer In Complex With 5-{2-[2-(2-Oxo-4-Sulfanylidene-3,4-Dihydropyrimidin-1(2H)-Yl)Ethoxy]Phenoxy}Naphthalene-2-Carbonitrile (Jlj648), A Non-Nucleoside Inhibitor
Organism: Human immunodeficiency virus 1
Method: ELECTRON MICROSCOPY Resolution:3.43 Å Release Date: 2025-09-10 Classification: VIRAL PROTEIN Ligands: A1BTU |
Organism: Human immunodeficiency virus 1
Method: ELECTRON MICROSCOPY
Release Date: 2025-09-10
Ligands: A1BTU
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Crystal Structure Of Dihydrofolate Reductase (Dhfr) From The Filarial Nematode W. Bancrofti In Complex With Nadph And [2-({4-[(2-Amino-4-Oxo-4,7-Dihydro-3H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Methyl]Benzene-1-Carbonyl}Amino)-4-Methoxyphenyl]Acetic Acid (Tsd10 Or Oed)
Organism: Wuchereria bancrofti
Method: X-RAY DIFFRACTION Resolution:1.79 Å Release Date: 2025-08-27 Classification: OXIDOREDUCTASE Ligands: NDP, OED |
Organism: Wuchereria bancrofti
Method: X-RAY DIFFRACTION
Release Date: 2025-08-27
Ligands: NDP, OED
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Crystal Structure Of Dihydrofolate Reductase (Dhfr) From The Filarial Nematode W. Bancrofti In Complex With Nadph And [2-({4-[(2-Amino-4-Oxo-4,7-Dihydro-3H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Methyl]Benzene-1-Carbonyl}Amino)-4-Cyanophenyl]Acetic Acid (Tsd25 Or Ofd)
Organism: Wuchereria bancrofti
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2025-08-27 Classification: OXIDOREDUCTASE Ligands: NAP, OFD |
Organism: Wuchereria bancrofti
Method: X-RAY DIFFRACTION
Release Date: 2025-08-27
Ligands: NAP, OFD
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Crystal Structure Of Dihydrofolate Reductase (Dhfr) From The Filarial Nematode W. Bancrofti In Complex With Nadph And Methotrexate (Mtx)
Organism: Wuchereria bancrofti
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2025-08-27 Classification: OXIDOREDUCTASE Ligands: NAP, MTX |
Organism: Wuchereria bancrofti
Method: X-RAY DIFFRACTION
Release Date: 2025-08-27
Ligands: NAP, MTX
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Crystal Structure Of Dihydrofolate Reductase (Dhfr) From The Filarial Nematode W. Bancrofti In Complex With Nadph And Antifolate 2-({4-[(2-Amino-4-Oxo-4,7-Dihydro-1H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Methyl]Benzene-1-Carbonyl}Amino)Benzoic Acid (Og7 Or Tsd001)
Organism: Wuchereria bancrofti
Method: X-RAY DIFFRACTION Resolution:2.91 Å Release Date: 2025-08-27 Classification: OXIDOREDUCTASE Ligands: NAP, OG7 |
Organism: Wuchereria bancrofti
Method: X-RAY DIFFRACTION
Release Date: 2025-08-27
Ligands: NAP, OG7
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Crystal Structure Of Hiv-1 Reverse Transcriptase (Y181C) Varient In Complex With 8-(2-(2-(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Ethoxy)Phenoxy)Indolizine-2-Carbonitrile (Jlj555), A Non-Nucleoside Inhibitor
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION Resolution:3.09 Å Release Date: 2023-11-29 Classification: VIRAL PROTEIN Ligands: 29T |
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION
Release Date: 2023-11-29
Ligands: 29T
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Crystal Structure Of Hiv-1 Reverse Transcriptase (Y181C) Varient In Complex With 5-(2-(2-(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Ethoxy)Phenoxy)-2-Naphthonitrile (Jlj600), A Non-Nucleoside Inhibitor
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION Resolution:2.96 Å Release Date: 2023-11-29 Classification: VIRAL PROTEIN Ligands: 3LQ, MG |
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION
Release Date: 2023-11-29
Ligands: 3LQ, MG
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Crystal Structure Of Hiv-1 Reverse Transcriptase (Y181C) Varient In Complex With 5-(2-(2-(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Ethoxy)-4-Fluorophenoxy)-7-Fluoro-2-Naphthonitrile (Jlj636), A Non-Nucleoside Inhibitor
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION Resolution:2.77 Å Release Date: 2023-11-29 Classification: VIRAL PROTEIN Ligands: 7N1 |
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION
Release Date: 2023-11-29
Ligands: 7N1
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Crystal Structure Of Hiv-1 Reverse Transcriptase (Y181C, V106A) Varient In Complex With 5-(2-(2-(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Ethoxy)-4-Fluorophenoxy)-7-Fluoro-2-Naphthonitrile (Jlj636), A Non-Nucleoside Inhibitor
Organism: Human immunodeficiency virus type 1 bh10, Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION Resolution:3.02 Å Release Date: 2023-11-29 Classification: VIRAL PROTEIN, Hydrolase Ligands: 7N1, MG |
Organism: Human immunodeficiency virus type 1 bh10, Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION
Release Date: 2023-11-29
Ligands: 7N1, MG
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Crystal Structure Of Hiv-1 Reverse Transcriptase (Y181C, V106A) Varient In Complex With 8-(2-(2-(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Ethoxy)Phenoxy)Indolizine-2-Carbonitrile (Jlj555), A Non-Nucleoside Inhibitor
Organism: Human immunodeficiency virus type 1 bh10
Method: X-RAY DIFFRACTION Resolution:2.62 Å Release Date: 2023-11-29 Classification: VIRAL PROTEIN Ligands: MG, 29T |
Organism: Human immunodeficiency virus type 1 bh10
Method: X-RAY DIFFRACTION
Release Date: 2023-11-29
Ligands: MG, 29T
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Crystal Structure Of Hiv-1 Reverse Transcriptase (Y181C, V106A) Variant In Complex With 8-(2-(2-(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Ethoxy)-4-Fluorophenoxy)-6-Fluoroindolizine-2-Carbonitrile (Jlj578), A Non-Nucleoside Inhibitor
Organism: Human immunodeficiency virus type 1 bh10
Method: X-RAY DIFFRACTION Resolution:2.76 Å Release Date: 2023-11-29 Classification: VIRAL PROTEIN, Hydrolase Ligands: MG, H9Y |
Organism: Human immunodeficiency virus type 1 bh10
Method: X-RAY DIFFRACTION
Release Date: 2023-11-29
Ligands: MG, H9Y
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Crystal Structure Of Hiv-1 Reverse Transcriptase (Y181C, V106A) Variant In Complex With 5-(2-(2-(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Ethoxy)Phenoxy)-2-Naphthonitrile (Jlj600), A Non-Nucleoside Inhibitor
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION Resolution:2.78 Å Release Date: 2023-11-29 Classification: VIRAL PROTEIN, Hydrolase Ligands: SO4, EDO, 3LQ, MG |
Organism: Human immunodeficiency virus 1
Method: X-RAY DIFFRACTION
Release Date: 2023-11-29
Ligands: SO4, EDO, 3LQ, MG
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Crystal Structure Of Dihydrofolate Reductase (Dhfr) From The Filarial Nematode W. Bancrofti In Complex With Nadph And Folate
Organism: Wuchereria bancrofti
Method: X-RAY DIFFRACTION Resolution:2.47 Å Release Date: 2023-05-10 Classification: OXIDOREDUCTASE Ligands: NAP, FOL, NA |
Organism: Wuchereria bancrofti
Method: X-RAY DIFFRACTION
Release Date: 2023-05-10
Ligands: NAP, FOL, NA
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Crystal Structure Of Hiv-1 Reverse Transcriptase In Complex With (E)-3-(3-Chloro-5-(2-(2-(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Ethoxy)-4-(2-Morpholinoethoxy)Phenoxy)Phenyl)Acrylonitrile (Jlj530)
Organism: Human immunodeficiency virus type 1, Human immunodeficiency virus type 1 group m subtype b (isolate bh10)
Method: X-RAY DIFFRACTION Resolution:2.89 Å Release Date: 2022-03-16 Classification: HYDROLASE, Transferase/Viral Protein Ligands: 9UV |
Organism: Human immunodeficiency virus type 1, Human immunodeficiency virus type 1 group m subtype b (isolate bh10)
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: 9UV
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Crystal Structure Of Hiv-1 Reverse Transcriptase In Complex With 6-((2-((4-Cyanophenyl)Amino)Pyrimidin-4-Yl)Amino)-5,7-Dimethylindolizine-2-Carbonitrile (Jlj604)
Organism: Human immunodeficiency virus type 1, Human immunodeficiency virus type 1 group m subtype b (isolate bh10)
Method: X-RAY DIFFRACTION Resolution:2.37 Å Release Date: 2022-03-16 Classification: HYDROLASE, Transferase/Viral Protein Ligands: 9WI, SO4, MG, PUT |
Organism: Human immunodeficiency virus type 1, Human immunodeficiency virus type 1 group m subtype b (isolate bh10)
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: 9WI, SO4, MG, PUT
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Crystal Structure Of Hiv-1 Reverse Transcriptase In Complex With (E)-4-((4-((4-(2-Cyanovinyl)-2,6-Dimethylphenyl)Amino)-6-(3-Morpholinopropoxy)-1,3,5-Triazin-2-Yl)Amino)Benzonitrile (Jlj564)
Organism: Human immunodeficiency virus type 1, Human immunodeficiency virus type 1 group m subtype b (isolate bh10)
Method: X-RAY DIFFRACTION Resolution:2.73 Å Release Date: 2022-03-16 Classification: HYDROLASE, Transferase/Viral Protein Ligands: 9W3 |
Organism: Human immunodeficiency virus type 1, Human immunodeficiency virus type 1 group m subtype b (isolate bh10)
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: 9W3