Search Count: 49
 |
Crystal Structure Of Menin In Complex With Inhibitor Compound 15
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2025-01-15 Classification: PROTEIN BINDING/INHIBITOR Ligands: A1AVE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-15
Ligands: A1AVE
 |
Crystal Structure Of Menin In Complex With Inhibitor Compound 26
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2025-01-15 Classification: PROTEIN BINDING/INHIBITOR Ligands: A1AVF, K, EPE, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-15
Ligands: A1AVF, K, EPE, SO4
 |
Crystal Structure Of Menin In Complex With Inhibitor Compound 20
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2025-01-15 Classification: PROTEIN BINDING/INHIBITOR Ligands: A1AVG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-15
Ligands: A1AVG
 |
Crystal Structure Of Non-Receptor Protein Tyrosine Phosphatase Shp2 In Complex With Inhibitor Compound 7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2024-01-03 Classification: HYDROLASE/INHIBITOR Ligands: W8I |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-01-03
Ligands: W8I
 |
Crystal Structure Of Non-Receptor Protein Tyrosine Phosphatase Shp2 In Complex With Inhibitor Compound 24
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.06 Å Release Date: 2024-01-03 Classification: HYDROLASE/INHIBITOR Ligands: WAB |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-01-03
Ligands: WAB
 |
Kras G12D In Complex With Mrtx-1133
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.30 Å Release Date: 2021-12-22 Classification: Hydrolase/Hydrolase Inhibitor Ligands: GDP, 6IC, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-12-22
Ligands: GDP, 6IC, MG
 |
Crystal Structure Of Kras G12D With Compound 15 (4-(4-[(1R,5S)-3,8-Diazabicyclo[3.2.1]Octan-3-Yl]-8-Fluoro-2-{[(2S)-1-Methylpyrrolidin-2-Yl]Methoxy}Pyrido[4,3-D]Pyrimidin-7-Yl)Naphthalen-2-Ol) Bound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.27 Å Release Date: 2021-12-22 Classification: HYDROLASE/INHIBITOR Ligands: GDP, MG, 7L8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-12-22
Ligands: GDP, MG, 7L8
 |
Crystal Structure Of Kras G12D With Compound 25 (4-(4-[(1R,5S)-3,8-Diazabicyclo[3.2.1]Octan-3-Yl]-8-Fluoro-2-{[(2R,4R,7As)-2-Fluorotetrahydro-1H-Pyrrolizin-7A(5H)-Yl]Methoxy}Pyrido[4,3-D]Pyrimidin-7-Yl)Naphthalen-2-Ol) Bound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.59 Å Release Date: 2021-12-22 Classification: HYDROLASE/INHIBITOR Ligands: GDP, MG, 7NL, GOL, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-12-22
Ligands: GDP, MG, 7NL, GOL, EDO
 |
Crystal Structure Of Kras G12D With Compound 24 (4-(4-[(1R,5S)-3,8-Diazabicyclo[3.2.1]Octan-3-Yl]-8-Fluoro-2-{[(2S,4S,7Ar)-2-Fluorotetrahydro-1H-Pyrrolizin-7A(5H)-Yl]Methoxy}Pyrido[4,3-D]Pyrimidin-7-Yl)Naphthalen-2-Ol) Bound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.56 Å Release Date: 2021-12-22 Classification: HYDROLASE/INHIBITOR Ligands: GDP, 7NZ, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-12-22
Ligands: GDP, 7NZ, MG
 |
Kras G12D In Complex With Compound 5B (7-(8-Chloronaphthalen-1-Yl)-8-Fluoro-2-{[(2S)-1-Methylpyrrolidin-2-Yl]Methoxy}-4-(Piperazin-1-Yl)Pyrido[4,3-D]Pyrimidine)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2021-12-22 Classification: HYDROLASE/INHIBITOR Ligands: GDP, MG, 7IZ, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-12-22
Ligands: GDP, MG, 7IZ, GOL
 |
Crystal Structure Of Kras G12D With Compound 36 (4-[(1R,5S)-3,8-Diazabicyclo[3.2.1]Octan-3-Yl]-7-(8-Ethynyl-7-Fluoronaphthalen-1-Yl)-8-Fluoro-2-{[(4S,7As)-Tetrahydro-1H-Pyrrolizin-7A(5H)-Yl]Methoxy}Pyrido[4,3-D]Pyrimidine) Bound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.29 Å Release Date: 2021-12-22 Classification: HYDROLASE/INHIBITOR Ligands: GDP, 7OE, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-12-22
Ligands: GDP, 7OE, MG
 |
Synthetic Glycoform Of Human Interleukin 6
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2021-04-07 Classification: CYTOKINE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-04-07
 |
Identification Of The Clinical Development Candidate Mrtx849, A Covalent Krasg12C Inhibitor For The Treatment Of Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2020-04-22 Classification: HYDROLASE/INHIBITOR Ligands: GDP, MG, M1R |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: GDP, MG, M1R
 |
Identification Of The Clinical Development Candidate Mrtx849, A Covalent Krasg12C Inhibitor For The Treatment Of Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.03 Å Release Date: 2020-04-22 Classification: HYDROLASE/INHIBITOR Ligands: GDP, MG, QH4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: GDP, MG, QH4
 |
Identification Of The Clinical Development Candidate Mrtx849, A Covalent Krasg12C Inhibitor For The Treatment Of Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2020-04-22 Classification: HYDROLASE/INHIBITOR Ligands: GDP, MG, M1X |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: GDP, MG, M1X
 |
Mtfp* Closed Conformation: I197C-Y200H-Y204H Mutant For Enhanced Metal Binding
Organism: Clavularia sp.
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2020-01-01 Classification: FLUORESCENT PROTEIN |
Organism: Clavularia sp.
Method: X-RAY DIFFRACTION
Release Date: 2020-01-01
 |
Mtfp* Open Conformation: I197C-Y200H-Y204H Mutant For Enhanced Metal Binding
Organism: Clavularia sp.
Method: X-RAY DIFFRACTION Resolution:1.65 Å Release Date: 2020-01-01 Classification: FLUORESCENT PROTEIN |
Organism: Clavularia sp.
Method: X-RAY DIFFRACTION
Release Date: 2020-01-01
 |
Mtfp* Closed Conformation: I197E-Y200H-Y204H Mutant For Enhanced Metal Binding
Organism: Clavularia sp.
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2020-01-01 Classification: FLUORESCENT PROTEIN |
Organism: Clavularia sp.
Method: X-RAY DIFFRACTION
Release Date: 2020-01-01
 |
Crystal Structure Of Glucokinase In Complex With Compound 6
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2019-07-10 Classification: Transferase/Transferase Inhibitor Ligands: GLC, HKM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-10
Ligands: GLC, HKM
 |
Crystal Structure Of Glucokinase In Complex With Compound 72
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2019-07-10 Classification: Transferase/Transferase Inhibitor Ligands: GLC, DMS, HKG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-10
Ligands: GLC, DMS, HKG