Search Count: 9
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Structure Of Kras-G12C Bound To 1-[(4Ar,10P,13R)-10-[5-Amino-4-Fluoro-3-Methyl-2-(Trifluoromethyl)Phenyl]-11-Chloro-9-Fluoro-1,2,4A,5-Tetrahydropyrazino[1',2':4,5][1,4]Oxazino[2,3-C]Quinolin-3(4H)-Yl]Prop-2-En-1-One (Compound 15)
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: MG, GDP, A1CII, PEG, GOL, DMS, ACT |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: MG, GDP, A1CII, PEG, GOL, DMS, ACT
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Structure Of Kras G12C Bound To Compound 4
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: A1CQ2, GDP, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: A1CQ2, GDP, MG
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Structure Of Kras G12C Bound To Divarasib (Gdc6036)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: GDP, MG, DMS, EDO, A1AWR, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: GDP, MG, DMS, EDO, A1AWR, PEG
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Kras-G13D-Gdp In Complex With Cpd5 (1-((S)-10-(6-Amino-4-Methyl-3-(Trifluoromethyl)Pyridin-2-Yl)-11-Chloro-7-(((2S,4R)-4-Fluoro-1-Methylpyrrolidin-2-Yl)Methoxy)-3,4,13,13A-Tetrahydropyrazino[2',1':3,4][1,4]Oxazepino[5,6,7-De]Quinazolin-2(1H)-Yl)Prop-2-En-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2023-12-20 Classification: HYDROLASE,ONCOPROTEIN/INHIBITOR Ligands: XOI, GDP, CL, MG, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-12-20
Ligands: XOI, GDP, CL, MG, EDO
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Kras-G13D-Gdp In Complex With Cpd36 ((E)-1-((3S)-4-(7-(6-Amino-4-Methyl-3-(Trifluoromethyl)Pyridin-2-Yl)-6-Chloro-8-Fluoro-2-(((S)-2-Methylenetetrahydro-1H-Pyrrolizin-7A(5H)-Yl)Methoxy)Quinazolin-4-Yl)-3-Methylpiperazin-1-Yl)-3-(4-((Dimethylamino)Methyl)-5-Methylpyridin-2-Yl)Prop-2-En-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.57 Å Release Date: 2023-12-20 Classification: HYDROLASE,ONCOPROTEIN/INHIBITOR Ligands: MG, GDP, XV3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-12-20
Ligands: MG, GDP, XV3
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Kras-G13D-Gdp In Complex With Cpd38 ((E)-1-((3S)-4-(7-(6-Amino-4-Methyl-3-(Trifluoromethyl)Pyridin-2-Yl)-6-Chloro-8-Fluoro-2-(((S)-2-Methylenetetrahydro-1H-Pyrrolizin-7A(5H)-Yl)Methoxy)Quinazolin-4-Yl)-3-Methylpiperazin-1-Yl)-3-(1,2,3,4-Tetrahydroisoquinolin-8-Yl)Prop-2-En-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.31 Å Release Date: 2023-12-20 Classification: HYDROLASE,ONCOPROTEIN/INHIBITOR Ligands: GOL, GDP, MG, XQ6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-12-20
Ligands: GOL, GDP, MG, XQ6
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Egfr Transmembrane - Juxtamembrane (Tm-Jm) Segment In Bicelles: Md Guided Nmr Refined Structure.
Organism: Homo sapiens
Method: SOLUTION NMR Release Date: 2013-02-20 Classification: SIGNALING PROTEIN |
Organism: Homo sapiens
Method: SOLUTION NMR
Release Date: 2013-02-20
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Crystal Structure Of The Inactive Egfr Kinase Domain In Complex With Amp-Pnp
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.96 Å Release Date: 2009-07-21 Classification: TRANSFERASE Ligands: ANP, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-07-21
Ligands: ANP, MG
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Je-2147-Hiv Protease Complex
Organism: Human immunodeficiency virus
Method: X-RAY DIFFRACTION Resolution:1.09 Å Release Date: 2002-04-03 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: JE2, CL, EDO |
Organism: Human immunodeficiency virus
Method: X-RAY DIFFRACTION
Release Date: 2002-04-03
Ligands: JE2, CL, EDO