Search Count: 34
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Kras G12C In Complex With G-2897
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2022-03-16 Classification: HYDROLASE/Immune System Ligands: Z07, GDP, MG, ACT, CAD, P15, EDO, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: Z07, GDP, MG, ACT, CAD, P15, EDO, DMS
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Crystal Structure Of Kas G12C In Complex With 2H11 Clamp
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2022-03-16 Classification: Hydrolase/Immune System Ligands: GDP, MG, CAC, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: GDP, MG, CAC, EDO
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Crystal Structure Of Gne-1952 Alkylated Kras G12C In Complex With 2H11 Clamp
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2022-03-16 Classification: Hydrolase/Immune System Ligands: MKZ, GDP, MG, GOL, EDO, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: MKZ, GDP, MG, GOL, EDO, SO4
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Crystal Structure Of Kras G12C In Complex With Gne-1952
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2022-03-16 Classification: HYDROLASE Ligands: MKZ, GDP, MG, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-03-16
Ligands: MKZ, GDP, MG, GOL
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Crystal Structure Of Hpk1 In Complex With Compound 2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.33 Å Release Date: 2022-01-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2YE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-05
Ligands: 2YE
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Crystal Structure Of Hpk1 In Complex With Gne1858
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2022-01-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: F97, EDO, MES |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-05
Ligands: F97, EDO, MES
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Crystal Structure Of Hpk1 In Complex With Compound 14
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2022-01-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2WI, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-05
Ligands: 2WI, SO4
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Crystal Structure Of Hpk1 In Complex With Compound 17
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2022-01-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2TR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-05
Ligands: 2TR
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Pim1 In Complex With Cpd16 (5-Amino-N-(5-((4R,5R)-4-Amino-5-Fluoroazepan-1-Yl)-1-Methyl-1H-Pyrazol-4-Yl)-2-(2,6-Difluorophenyl)Thiazole-4-Carboxamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.71 Å Release Date: 2019-02-27 Classification: TRANSFERASE Ligands: GOL, PO4, KUV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-02-27
Ligands: GOL, PO4, KUV
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Pim1 Kinase In Complex With Cpd1 (1-Methyl-4-(3-(6-(Piperazin-1-Yl)Pyridin-2-Yl)-1H-Pyrazolo[3,4-C]Pyridin-5-Yl)Piperazin-2-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2018-04-18 Classification: TRANSFERASE/INHIBITOR Ligands: PO4, 971 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-04-18
Ligands: PO4, 971
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Usp7 In Complex With Cpd2 (4-(3-(1-Methylpiperidin-4-Yl)-1,2,4-Oxadiazol-5-Yl)Phenol)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.55 Å Release Date: 2017-12-13 Classification: HYDROLASE Ligands: AJJ, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-12-13
Ligands: AJJ, GOL
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Usp7 In Complex With Gne6640 (4-(2-Amino-4-Ethyl-5-(1H-Indazol-5-Yl)Pyridin-3-Yl)Phenol)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.84 Å Release Date: 2017-10-25 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 8JM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-10-25
Ligands: 8JM
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Usp7 In Complex With Gne6776 (6'-Amino-4'-Ethyl-5'-(4-Hydroxyphenyl)-N-Methyl-[3,3'-Bipyridine]-6-Carboxamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.23 Å Release Date: 2017-10-25 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 8JP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-10-25
Ligands: 8JP
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Pim1 Kinase In Complex With Cpd17 (1-(6-(4,4-Difluoropiperidin-3-Yl)Pyridin-2-Yl)-6-(6-Methylpyrazin-2-Yl)-1H-Pyrazolo[4,3-C]Pyridine)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.89 Å Release Date: 2017-05-10 Classification: TRANSFERASE/INHIBITOR Ligands: 96Y |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: 96Y
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Discovery Of 3,5-Substituted 6-Azaindazoles As Potent Pan-Pim Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2015-10-28 Classification: Transferase/Transferase Inhibitor Ligands: L20, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-28
Ligands: L20, PO4
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Pim1 In Complex With Cpd4 (3-Methyl-5-(Pyridin-3-Yl)-1H-Pyrazolo[3,4-C]Pyridine)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.46 Å Release Date: 2015-10-28 Classification: Transferase/Transferase Inhibitor Ligands: 5E5, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-28
Ligands: 5E5, PO4
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Pim1 In Complex With Cpd36 ((1S,3S)-N1-(6-(5-(Pyridin-3-Yl)-1H-Pyrazolo[3,4-C]Pyridin-3-Yl)Pyridin-2-Yl)Cyclohexane-1,3-Diamine)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2015-10-28 Classification: Transferase/Transferase Inhibitor Ligands: 5E6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-28
Ligands: 5E6
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Crystal Structure Of Erk2 In Complex With N-Cyclohexyl-9H-Purin-6-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2015-09-23 Classification: transferase/transferase inhibitor Ligands: EMU, IMD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-23
Ligands: EMU, IMD
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Crystal Structure Of Erks In Complex With 5-Chlorobenzo[D]Oxazol-2-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.23 Å Release Date: 2015-09-23 Classification: transferase/transferase inhibitor Ligands: 36R, IMD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-23
Ligands: 36R, IMD
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Crystal Structure Of Erk2 In Complex With (S)-2-((9H-Purin-6-Yl)Amino)-3-Phenylpropan-1-Ol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2015-09-23 Classification: transferase/transferase inhibitor Ligands: 36Q |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-23
Ligands: 36Q