Search Count: 27
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Egfr Kinase Domain Mutant "Tmlr" With Azabenzimidazole Compound 7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2016-09-07 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, 60B |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-09-07
Ligands: SO4, 60B
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Egfr Kinase Domain Mutant "Tmlr" With 3-Carboxamide Azaindole Compound 13
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.46 Å Release Date: 2016-09-07 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, 60D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-09-07
Ligands: SO4, 60D
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Egfr Kinase Domain Mutant "Tmlr" With 3-Azetidinyl Azaindazole Compound 21
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.62 Å Release Date: 2016-09-07 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, 60E |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-09-07
Ligands: SO4, 60E
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Egfr Kinase Domain Mutant "Tmlr" With Pyridone Compound 2: 4-[2-(4-Chlorophenyl)Ethylamino]-~{N}-[4-(4-Methylpiperazin-1-Yl)Phenyl]-2-Oxidanylidene-1~{H}-Pyridine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2015-12-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 5Q2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-12-30
Ligands: 5Q2
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Egfr Kinase Domain Mutant "Tmlr" With Pyridone Compound 19: 4-[(2-Azanylpyrimidin-4-Yl)Amino]-~{N}-[4-(4-Methylpiperazin-1-Yl)Phenyl]-2-Oxidanylidene-1~{H}-Pyridine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.78 Å Release Date: 2015-12-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, 5Q3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-12-30
Ligands: SO4, 5Q3
 |
Egfr Kinase Domain Mutant "Tmlr" With Pyridone Compound 13: 4-[(2-Methoxyphenyl)Amino]-~{N}-[4-(4-Methylpiperazin-1-Yl)Phenyl]-2-Oxidanylidene-1~{H}-Pyridine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.81 Å Release Date: 2015-12-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, 5Q4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-12-30
Ligands: SO4, 5Q4
 |
Egfr Kinase Domain With Pyridone Compound 13: 4-[(2-Methoxyphenyl)Amino]-~{N}-[4-(4-Methylpiperazin-1-Yl)Phenyl]-2-Oxidanylidene-1~{H}-Pyridine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2015-12-30 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 5Q4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-12-30
Ligands: 5Q4
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Cdk2 With Egfr Inhibitor Compound 8
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.63 Å Release Date: 2014-11-26 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ACT, 3QS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-26
Ligands: ACT, 3QS
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Egfr Kinase (T790M/L858R) With Inhibitor Compound 6
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.78 Å Release Date: 2014-11-26 Classification: Transferase/transferase inhibitor Ligands: 3QW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-26
Ligands: 3QW
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Egfr Kinase (T790M/L858R) With Inhibitor Compound 5
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.10 Å Release Date: 2014-11-26 Classification: Transferase/Transferase inhibitor Ligands: 3QY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-26
Ligands: 3QY
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Egfr Kinase (T790M/L858R) With Inhibitor Compound 4
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2014-11-26 Classification: Transferase/Transferase inhibitor Ligands: SO4, 3R0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-26
Ligands: SO4, 3R0
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Egfr Kinase (T790M/L858R) With Inhibitor Compound 1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.55 Å Release Date: 2014-11-26 Classification: Transferase/Transferase inhibitor Ligands: SO4, 3R1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-26
Ligands: SO4, 3R1
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Egfr Kinase (T790M/L858R) With Inhibitor Compound 8
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2014-11-26 Classification: Transferase/Transferase inhibitor Ligands: SO4, 3QS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-26
Ligands: SO4, 3QS
 |
Compound 21 (1-Alkyl-Substituted 1,2,4-Triazoles)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.78 Å Release Date: 2013-01-09 Classification: Transferase/Transferase Inhibitor Ligands: 17V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-01-09
Ligands: 17V
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Rational Design Of Pi3K-Alpha Inhibitors That Exhibit Selectivity Over The Pi3K-Beta Isoform
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2011-11-16 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3T8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-11-16
Ligands: 3T8
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Discovery Of Gdc-0980: A Potent, Selective, And Orally Available Class I Phosphatidylinositol 3-Kinase (Pi3K)/Mammalian Target Of Rapamycin (Mtor) Kinase Inhibitor For The Treatment Of Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.79 Å Release Date: 2011-11-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 980 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-11-02
Ligands: 980
 |
Structure-Based Design Of Thienobenzoxepin Inhibitors Of Pi3- Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2011-08-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: FAV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-08-03
Ligands: FAV
 |
Structure-Based Design Of Thienobenzoxepin Inhibitors Of Pi3-Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2011-08-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: FAZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-08-03
Ligands: FAZ
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Structure-Based Optimization Of Pyrazolo -Pyrimidine And -Pyridine Inhibitors Of Pi3-Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2010-12-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: NZS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-12-29
Ligands: NZS
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Structure-Based Optimization Of Pyrazolo -Pyrimidine And -Pyridine Inhibitors Of Pi3-Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2010-12-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: NZU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-12-29
Ligands: NZU