Search Count: 44
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Crystal Structure Of The Complex Between Vhl, Elonginb, Elonginc, And Compound 5
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:2.47 Å Release Date: 2024-05-29 Classification: TRANSCRIPTION Ligands: TFA, PEG, EDO, ACT, DMS |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2024-05-29
Ligands: TFA, PEG, EDO, ACT, DMS
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Crystal Structure Of The Complex Between Vhl, Elonginb, Elonginc, And Compound 5
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.99 Å Release Date: 2024-05-29 Classification: TRANSCRIPTION Ligands: EDO, DMS, CL, A1ARP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-05-29
Ligands: EDO, DMS, CL, A1ARP
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Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2023-10-11 Classification: HYDROLASE Ligands: SO4, YR2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-11
Ligands: SO4, YR2
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Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2023-10-11 Classification: HYDROLASE Ligands: SO4, YT2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-11
Ligands: SO4, YT2
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Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2023-10-11 Classification: HYDROLASE Ligands: ZH5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-11
Ligands: ZH5
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Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2023-10-11 Classification: HYDROLASE/INHIBITOR Ligands: ZJX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-11
Ligands: ZJX
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Structure Of Human Ripk1 Kinase Domain In Complex With Gne684
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2019-05-29 Classification: IMMUNE SYSTEM Ligands: L8D, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-29
Ligands: L8D, IOD
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Structure Of Human Ripk1 Kinase Domain In Complex With Compound 11
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2019-05-01 Classification: Transferase/Transferase inhibitor Ligands: L4Y |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-01
Ligands: L4Y
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Dlk In Complex With Compound 10 (5-(1-Isopropyl-5-(3-(Oxetan-3-Yl)-3-Azabicyclo[3.1.0]Hexan-6-Yl)-1H-Pyrazol-3-Yl)-3-(Trifluoromethyl)Pyridin-2-Amine)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2017-10-04 Classification: TRANSFERASE/TRANSFERASE Inhibitor Ligands: 9FS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-10-04
Ligands: 9FS
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Dlk In Complex With Inhibitor 5-(1-Isopropyl-5-(1-(Oxetan-3-Yl)Piperidin-4-Yl)-1H-Pyrazol-3-Yl)-3-(Trifluoromethyl)Pyridin-2-Amine (Compound 7)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.96 Å Release Date: 2017-10-04 Classification: TRANSFERASE/TRANSFERASE Inhibitor Ligands: 9FV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-10-04
Ligands: 9FV
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Crystal Structure Of Pyrrolidine Amide Inhibitor [(3S)-3-(4-Bromo-1H-Pyrazol-1-Yl)Pyrrolidin-1-Yl][3-(Propan-2-Yl)-1H-Pyrazol-5-Yl]Methanone (Compound 35) In Complex With Kdm5A
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2017-05-10 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NI, ZN, 90S, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: NI, ZN, 90S, SO4
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Crystal Structure Of Selective Pyrrolidine Amide Kdm5A Inhibitor N-{(3R)-1-[3-(Propan-2-Yl)-1H-Pyrazole-5-Carbonyl]Pyrrolidin-3-Yl}Cyclopropanecarboxamide (Compound 48)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.05 Å Release Date: 2017-05-10 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: NI, ZN, 90V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: NI, ZN, 90V
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Structure Of The Human Glun1/Glun2A Lbd In Complex With Compound 2 (Gne9178)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2016-11-30 Classification: TRANSPORT PROTEIN Ligands: ACT, GLU, 7H0, CA, GLY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-30
Ligands: ACT, GLU, 7H0, CA, GLY
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Structure Of The Human Glun1/Glun2A Lbd In Complex With Compound 9 (Gne3500)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.48 Å Release Date: 2016-11-30 Classification: TRANSPORT PROTEIN Ligands: GLU, 7H2, GLY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-30
Ligands: GLU, 7H2, GLY
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Crystal Structure Of Kdm5A In Complex With A Naphthyridone Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.18 Å Release Date: 2016-08-10 Classification: Oxidoreductase/Inhibitor Ligands: NI, ZN, 6QN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-08-10
Ligands: NI, ZN, 6QN
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Structure Of The Human Glun1/Glun2A Lbd In Complex With Gne0723
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2016-07-13 Classification: TRANSPORT PROTEIN Ligands: ACT, GLU, 6RV, GLY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-07-13
Ligands: ACT, GLU, 6RV, GLY
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Structure Of The Human Glun1/Glun2A Lbd In Complex With 7-{[Ethyl(4-Fluorophenyl)Amino]Methyl}-N,2-Dimethyl-5-Oxo-5H-[1,3]Thiazolo[3,2-A]Pyrimidine-3-Carboxamide (Compound 19)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.86 Å Release Date: 2016-03-16 Classification: TRANSPORT PROTEIN Ligands: GLU, GLY, 67H |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-03-16
Ligands: GLU, GLY, 67H
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Structure Of The Human Glun1/Glun2A Lbd In Complex With N-Ethyl-7-{[2-Fluoro-3-(Trifluoromethyl)Phenyl]Methyl}-2-Methyl-5-Oxo-5H-[1,3]Thiazolo[3,2-A]Pyrimidine-3-Carboxamide (Compound 29)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.12 Å Release Date: 2016-03-16 Classification: TRANSPORT PROTEIN Ligands: CA, GLU, 67J, EPE, GLY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-03-16
Ligands: CA, GLU, 67J, EPE, GLY
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Crystal Structure Of Dlk (Kinase Domain)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2015-10-14 Classification: TRANSFERASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-14
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Dlk In Complex With Inhibitor 2-((6-(3,3-Difluoropyrrolidin-1-Yl)-4-(1-(Oxetan-3-Yl)Piperidin-4-Yl)Pyridin-2-Yl)Amino)Isonicotinonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.28 Å Release Date: 2015-10-14 Classification: TRANSFERASE/TRANSFERASE Inhibitor Ligands: 50D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-14
Ligands: 50D