Search Count: 17
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Structure Of Kras G12C Bound To Compound 4
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: A1CQ2, GDP, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: A1CQ2, GDP, MG
 |
Structure Of Kras G12C Bound To Divarasib (Gdc6036)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: GDP, MG, DMS, EDO, A1AWR, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: GDP, MG, DMS, EDO, A1AWR, PEG
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Crystal Structure Of Human Cyclic Gmp-Amp Synthase (Cgas) In Complex With Compound 5; 3-((2-((3-Chloro-4-Fluorophenyl)Amino)-2-Oxoethyl)Carbamoyl)Picolinic Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.53 Å Release Date: 2025-01-01 Classification: TRANSFERASE Ligands: ANP, A1BJH, ZN, MN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: ANP, A1BJH, ZN, MN
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Crystal Structure Of Human Cyclic Gmp-Amp Synthase (Cgas) In Complex With Compound 36; (S)-(6,7-Dichloro-1-Methyl-1,3,4,5-Tetrahydro-2H-Pyrido[4,3-B]Indol-2-Yl)(5-(2-Hydroxyethoxy)Pyrimidin-2-Yl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.25 Å Release Date: 2025-01-01 Classification: TRANSFERASE Ligands: ZN, A1BJA, ANP, MN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: ZN, A1BJA, ANP, MN
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Crystal Structure Of Human Cyclic Gmp-Amp Synthase (Cgas) In Complex With Compound 23; (S)-1-(6,7-Dichloro-1-Methyl-1,3,4,5-Tetrahydro-2H-Pyrido[4,3-B]Indol-2-Yl)-2-Methoxyethan-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2025-01-01 Classification: TRANSFERASE Ligands: ZN, A1BJD, ANP, MN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: ZN, A1BJD, ANP, MN
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Cdk2 In Complex With Cpd14 (5-Fluoro-4-(4-Methyl-5,6,7,8-Tetrahydro-4H-Pyrazolo[1,5-A]Azepin-3-Yl)-N-(5-(4-Methylpiperazin-1-Yl)Pyridin-2-Yl)Pyrimidin-2-Amine)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2020-07-29 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: N14 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-07-29
Ligands: N14
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Cdk6 In Complex With Cpd13 (R)-5-Fluoro-4-(4-Methyl-5,6,7,8-Tetrahydro-4H-Pyrazolo[1,5-A]Azepin-3-Yl)-N-(5-(4-Methylpiperazin-1-Yl)Pyridin-2-Yl)Pyrimidin-2-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.71 Å Release Date: 2020-07-29 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: N1A |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-07-29
Ligands: N1A
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Cdk6 In Complex With Cpd24 N-(5-(6-Ethyl-2,6-Diazaspiro[3.3]Heptan-2-Yl)Pyridin-2-Yl)-5-Fluoro-4-(4-Methyl-5,6,7,8-Tetrahydro-4H-Pyrazolo[1,5-A]Azepin-3-Yl)Pyrimidin-2-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2020-07-29 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: N1J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-07-29
Ligands: N1J
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Crebbp Bromodomain In Complex With Cpd 4 (1-(1-(Cyclopropylmethyl)-3-(1H-Indol-4-Yl)-1,4,6,7-Tetrahydro-5H-Pyrazolo[4,3-C]Pyridin-5-Yl)Ethan-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.39 Å Release Date: 2018-08-08 Classification: PROTEIN BINDING/INHIBITOR Ligands: DMS, EDO, BKD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-08-08
Ligands: DMS, EDO, BKD
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Crebbp Bromodomain In Complex With Cpd3 ((S)-1-(3-(6-(1-Methyl-1H-Pyrazol-4-Yl)-3,4-Dihydroquinolin-1(2H)-Yl)-1-(Tetrahydrofuran-3-Yl)-1,4,6,7-Tetrahydro-5H-Pyrazolo[4,3-C]Pyridin-5-Yl)Ethan-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2018-03-07 Classification: TRANSCRIPTION REGULATOR/INHIBITOR Ligands: 9U7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-07
Ligands: 9U7
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Crebbp Bromodomain In Complex With Cpd8 (1-(3-(7-(Difluoromethyl)-6-(1-Methyl-1H-Pyrazol-4-Yl)-3,4-Dihydroquinolin-1(2H)-Yl)-1-(Tetrahydrofuran-3-Yl)-1,4,6,7-Tetrahydro-5H-Pyrazolo[4,3-C]Pyridin-5-Yl)Ethan-1-One)
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.43 Å Release Date: 2018-03-07 Classification: TRANSFERASE/INHIBITOR Ligands: 9UA, DMS, GOL |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2018-03-07
Ligands: 9UA, DMS, GOL
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Crebbp Bromodomain In Complex With Cpd10 (1-(3-(7-(Difluoromethyl)-6-(1-Methyl-1H-Pyrazol-4-Yl)-3,4-Dihydroquinolin-1(2H)-Yl)-1-(Tetrahydro-2H-Pyran-4-Yl)-1,4,6,7-Tetrahydro-5H-Pyrazolo[4,3-C]Pyridin-5-Yl)Ethan-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2018-03-07 Classification: TRANSCRIPTION REGULATOR/INHIBITOR Ligands: 9UD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-07
Ligands: 9UD
 |
Crebbp Bromodomain In Complex With Cpd17 (N,2,7-Trimethyl-2,3-Dihydro-4H-Benzo[B][1,4]Oxazine-4-Carboxamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2018-03-07 Classification: TRANSCRIPTION REGULATOR/INHIBITOR Ligands: SO4, 9UG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-07
Ligands: SO4, 9UG
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Crebbp Bromodomain In Complex With Cpd19 (3-(7-(Difluoromethyl)-6-(1-Methyl-1H-Pyrazol-4-Yl)-3,4-Dihydroquinolin-1(2H)-Yl)-N-Methyl-1-(Tetrahydro-2H-Pyran-4-Yl)-1,4,6,7-Tetrahydro-5H-Pyrazolo[4,3-C]Pyridine-5-Carboxamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.41 Å Release Date: 2018-02-21 Classification: TRANSCRIPTION REGULATOR/INHIBITOR Ligands: 9U4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-02-21
Ligands: 9U4
 |
Crebbp Bromodomain In Complex With Cpd6 (Methyl 1H-Indole-3-Carboxylate)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.30 Å Release Date: 2018-02-21 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: DMS, C2Y |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-02-21
Ligands: DMS, C2Y
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Crebbp Bromodomain In Complex With Cpd16 (5-(7-(Difluoromethyl)-6-(1-Methyl-1H-Pyrazol-4-Yl)-3,4-Dihydroquinolin-1(2H)-Yl)-N-Methyl-1H-Indole-3-Carboxamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.39 Å Release Date: 2018-02-21 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: C3J, EDO, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-02-21
Ligands: C3J, EDO, NA
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Crebbp Bromodomain In Complex With Cpd17 (5-(7-(Difluoromethyl)-6-(1-Methyl-1H-Pyrazol-4-Yl)-3,4-Dihydroquinolin-1(2H)-Yl)-3-Methylbenzo[D]Thiazol-2(3H)-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.44 Å Release Date: 2018-02-21 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: C3V, SO4, DMS, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-02-21
Ligands: C3V, SO4, DMS, GOL